A Modified Brain MR Image Segmentation and Bias Field Estimation Model Based on Local and Global Information

Because of the poor radio frequency coil uniformity and gradient-driven eddy currents, there is much noise and intensity inhomogeneity (bias) in brain magnetic resonance (MR) image, and it severely affects the segmentation accuracy. Better segmentation results are difficult to achieve by traditional methods; therefore, in this paper, a modified brain MR image segmentation and bias field estimation model based on local and global information is proposed. We first construct local constraints including image neighborhood information in Gaussian kernel mapping space, and then the complete regularization is established by introducing nonlocal spatial information of MR image. The weighting between local and global information is automatically adjusted according to image local information. At the same time, bias field information is coupled with the model, and it makes the model reduce noise interference but also can effectively estimate the bias field information. Experimental results demonstrate that the proposed algorithm has strong robustness to noise and bias field is well corrected

Image Segmentation by Fuzzy C-Means Clustering Algorithm with a Novel Penalty Term

To overcome the noise sensitiveness of conventional fuzzy c-means (FCM) clustering algorithm, a novel extended FCM algorithm for image segmentation is presented in this paper. The algorithm is developed by modifying the objective function of the standard FCM algorithm with a penalty term that takes into account the influence of the neighboring pixels on the centre pixels. The penalty term acts as a regularizer in this algorithm, which is inspired from the neighborhood expectation maximization algorithm and is modified in order to satisfy the criterion of the FCM algorithm. The performance of our algorithm is discussed and compared to those of many derivatives of FCM algorithm. Experimental results on segmentation of synthetic and real images demonstrate that the proposed algorithm is effective and robust

Brain MR Image Segmentation Based on an Adaptive Combination of Global and Local Fuzzy Energy

This paper presents a novel fuzzy algorithm for segmentation of brain MR images and simultaneous estimation of intensity inhomogeneity. The proposed algorithm defines an objective function including a local fuzzy energy and a global fuzzy energy. Based on the assumption that the local image intensities belonging to each different tissue satisfy Gaussian distributions with different means, we derive the local fuzzy energy by utilizing maximum a posterior probability (MAP) and Bayes rule. The global fuzzy energy is defined by measuring the distance between the original image and the corresponding inhomogeneity-free image. We combine the global fuzzy energy with the local fuzzy energy using an adaptive weight function whose value varies with the local contrast of the image. This combination enables the proposed algorithm to address intensity inhomogeneity and to improve the accuracy of segmentation and its robustness to initialization. Besides, the proposed algorithm incorporates neighborhood spatial information into the membership function to reduce the impact of noise. Experimental results for synthetic and real images validate the desirable performances of the proposed algorithm

Anisotropic mean shift based fuzzy c-means segmentation of deroscopy images

Image segmentation is an important task in analysing dermoscopy images as the extraction of the borders of skin lesions provides important cues for accurate diagnosis. One family of segmentation algorithms is based on the idea of clustering pixels with similar characteristics. Fuzzy c-means has been shown to work well for clustering based segmentation, however due to its iterative nature this approach has excessive computational requirements. In this paper, we introduce a new mean shift based fuzzy c-means algorithm that requires less computational time than previous techniques while providing good segmentation results. The proposed segmentation method incorporates a mean field term within the standard fuzzy c-means objective function. Since mean shift can quickly and reliably find cluster centers, the entire strategy is capable of effectively detecting regions within an image. Experimental results on a large dataset of diverse dermoscopy images demonstrate that the presented method accurately and efficiently detects the borders of skin lesions