243,557 research outputs found

    THE EFFORTS OF PUBLIC RELATIONS OF PT PLN  (PERSERO) APJ SURAKARTA TO SUCCESSFULLY  EXECUTE THE ELECTRICITY ECONOMIZING PROGRAM 

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    This final project report is written based on the job training in PT PLN (Persero) APJ Surakarta.   The job training was done on 2 nd  until 31 st  March, 2009. The major aim of this final project is to know  the   efforts   of   Public  Relations   of   PT   PLN  (Persero)  APJ   Surakarta   to   successfully   execute   the  electricity economizing program. In the discussion, the writer describes the efforts of Public Relations of PT PLN (Persero) APJ   Surakarta to successfully execute the electricity economizing program. There are the efforts for external  public and the efforts for internal public. The efforts for external public   are giving knowledge and  spreading information by making relationship with mass media, holding socialization about electricity  economizing program, creating and using Mr. and Mrs. Bili the clowns, making printed materials for  promotion and publication about electricity economizing program, and persuading society to turn off  light at 17.00 p.m. until 22.00 p.m. The efforts for internal public are holding campaign in PT PLN   (Persero)  APJ   Surakarta,   persuading   the   employees   of   PT   PLN  (Persero)  APJ   Surakarta   to   use  electricity economically, and turning off light of PT PLN (persero) APJ Surakarta at 17.00 p.m. until  22.00 p.m. The  implementation of   the program mostly  run well  even  though  the Public Relations  has  weaknesses; they are the budget and the facilities of Public Relations Division of PT PLN (Persero)  APJ Surakarta.  At last,  the writer gives some suggestions to Public Relations Division of PT PLN  (Persero) APJ Surakarta, such as increasing the quality and quantity of the facilities, improving the   skills of the officers in order to conform to their field, and increasing more budgets to support their  activities

    Two Writings of al-Ṭurṭūshī as Evidence for Early Muslim Reactions to the Frankish Crusader Presence in the Levant

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    This is the author accepted manuscript.Near-contemporaneous source material for the earliest Muslim responses to the arrival of the Frankish crusaders in the eastern Mediterranean at the end of the fifth/eleventh century is extremely scarce, with the result that modern attempts to reconstruct such reactions can be only very limited in scope. This article examines two writings by the Andalusī Muslim al-Ṭurṭūshī, who wrote in Alexandria at the beginning of the sixth/twelfth century, that have been almost completely ignored, and highlights his concern about the potential threat to Egypt, which was mainly caused by the Frankish advances in his homeland

    Protein refolding in an oscillatory flow reactor

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    We demonstrate that an oscillatory flow reactor is a viable reactor for protein refolding via direct dilution. The mixing characteristics of the oscillatory flow reactor are well described and controllable and, importantly, can be scaled-up to process scale without a loss of mixing efficiency. This makes the oscillatory flow reactor an attractive alternative to conventional stirred-tank reactors for process-scale renaturation

    Balanced anaesthesia 2005 : avoiding the transition from acute to chronic pain : review

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    When general anaesthesia consisted of the administration of a volatile anaesthetic agent according to clinical parameters usually preceded by premedication, was chronic post-operative pain a significant problem? Have we, by working hard to deliver balanced anaesthesia and rapid recovery lost sight of the fundamental importance of abolishing noxious reflexes at the spinal level? We need to identify, ameliorate and manage specific features and risk factors, including the severity of the acute pain experience, for individuals at risk for the development of a chronic pain syndrome. Anaesthetists\' actions and the drugs they use have multiple and profound effects to be taken into account, appropriately modified and controlled, combined with excellent postoperative analgesia, particularly for those patients or procedures at high risk to minimise the transition of acute to chronic pain following surgery. Acute nociceptive pain is the risk for the transition to chronic neuropathic pain. Southern African Journal of Anaesthetics and Analgesia Vol.11(1) 2005: 14-1

    Heterodimerization of apelin receptor and neurotensin receptor 1 induces phosphorylation of ERK1/2 and cell proliferation via Gαq-mediated mechanism

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    Dimerization of G protein-coupled receptors (GPCRs) is crucial for receptor function including agonist affinity, efficacy, trafficking and specificity of signal transduction, including G protein coupling. Emerging data suggest that the cardiovascular system is the main target of apelin, which exerts an overall neuroprotective role, and is a positive regulator of angiotensin-converting enzyme 2 (ACE2) in heart failure. Moreover, ACE2 cleaves off C-terminal residues of vasoactive peptides including apelin-13, and neurotensin that activate the apelin receptor (APJ) and neurotensin receptor 1 (NTSR1) respectively, that belong to the A class of GPCRs. Therefore, based on the similar mode of modification by ACE2 at peptide level, the homology at amino acid level and the capability of forming dimers with other GPCRs, we have been suggested that APJ and NTSR1 can form a functional heterodimer. Using co-immunoprecipitation, BRET and FRET, we provided conclusive evidence of heterodimerization between APJ and NTSR1 in a constitutive and induced form. Upon agonist stimulation, hetrodimerization enhanced ERK1/2 activation and increased proliferation via activation of Gq α-subunits. These novel data provide evidence for a physiological role of APJ/NTSR1 heterodimers in terms of ERK1/2 activation and increased intracellular calcium and induced cell proliferation and provide potential new pharmaceutical targets for cardiovascular disease. © 2014 The Authors
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