Study on the Mechanical Properties of Carbon Nanotube Coated‒Fiber Multi-Scale (CCFM) Hybrid Composites

L'abstract è presente nell'allegato / the abstract is in the attachmen

Unit Operations of Particulate Solids

Suitable for practicing engineers and engineers in training, this book covers the most important operations involving particulate solids. Through clear explanations of theoretical principles and practical laboratory exercises, the text provides an understanding of the behavior of powders and pulverized systems. It also helps readers develop skills for operating, optimizing, and innovating particle processing technologies and machinery in order to carry out industrial operations. The author explores common bulk solids processing operations, including milling, agglomeration, fluidization, mixing, and solid-fluid separation

Continuous blending of dry pharmaceutical powders

Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 2008.This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.Includes bibliographical references (p. 269-279).Conventional batch blending of pharmaceutical powders coupled with long quality analysis times increases the production cycle time leading to strained cash flows. Also, scale-up issues faced in process development causes delays in transforming a drug in research to a drug under commercial production. Continuous blending is as an attractive alternative design choice to batch process and is examined in this work. This work proposes to examine the feasibility of applying continuous blending in pharmaceutical manufacturing. Two kinds of blenders, a double helical ribbon blender and a Zigzag R blender were chosen as experimental systems representing high shear and moderate shear equipment. This work first focuses on developing a process understanding of continuous blending by examining the ow behavior of powders in experimental blenders using impulse stimulus response experiments and subsequent residence time distribution analysis. Powder ow behavior was modeled using an residence time distribution models like axial dispersion models. These ow behavior studies were followed by blender performance studies. The dependence of the mixing performance of the continuous blending system on different operational variables like rotation rates of mixing elements and raw material properties like particle size, shape and cohesion were studied. Mean residence time and time period of fluctuation in the concentration of active ingredient coming at the inlet were the two most important operational variables that affected blender performance. Larger particles and particles with less cohesion were seen to mix well with higher dispersion coefficients in a ribbon blender. A residence time distribution based process model for continuous blending was investigated and shown to depict the process well within experimental errors in determining the parameters of the residence time distribution model.(cont.) The predictive capability of the process model was found to dependent on the scale of scrutiny of the powder mixture in the blender. Choosing the correct scale of scrutiny was demonstrated to be of critical importance in determination of blend quality. Growing pressures on pharmaceutical industry due to patent expirations has forced manufacturers to look beyond the US and EU for potential manufacturing locations in addition to invest in novel manufacturing methods and technologies. The capstone work in this thesis proposes a framework that managers of pharmaceutical and biologics manufacturing can utilize to identify critical issues in globalization of manufacturing and in making strategic manufacturing location decisions.by Lakshman Pernenkil.Ph.D

16th European Symposium on Comminution and Classification: book of extended abstracts

Extended abstracts from the 16th European Symposium on Comminution and Classification, ESCC 2019 held at the University of Leeds, 2-4 September 2019. Based on the abstracts received, the symposium was structured in the following themes: fundamentals of size reduction, innovations in milling and classification, nanomilling, mechano-chemistry and solid state transformations, pharmaceuticals and foods, attrition and wear, and related modelling. The notable number of abstracts received on modelling made it possible to divide them in sub-themes: mechanistic, population balance, discrete element and coupling with computational fluid dynamics

Haptics: Science, Technology, Applications

This open access book constitutes the proceedings of the 12th International Conference on Human Haptic Sensing and Touch Enabled Computer Applications, EuroHaptics 2020, held in Leiden, The Netherlands, in September 2020. The 60 papers presented in this volume were carefully reviewed and selected from 111 submissions. The were organized in topical sections on haptic science, haptic technology, and haptic applications. This year's focus is on accessibility

International Conference on Civil Infrastructure and Construction (CIC 2020)

This is the proceedings of the CIC 2020 Conference, which was held under the patronage of His Excellency Sheikh Khalid bin Khalifa bin Abdulaziz Al Thani in Doha, Qatar from 2 to 5 February 2020. The goal of the conference was to provide a platform to discuss next-generation infrastructure and its construction among key players such as researchers, industry professionals and leaders, local government agencies, clients, construction contractors and policymakers. The conference gathered industry and academia to disseminate their research and field experiences in multiple areas of civil engineering. It was also a unique opportunity for companies and organizations to show the most recent advances in the field of civil infrastructure and construction. The conference covered a wide range of timely topics that address the needs of the construction industry all over the world and particularly in Qatar. All papers were peer reviewed by experts in their field and edited for publication. The conference accepted a total number of 127 papers submitted by authors from five different continents under the following four themes: Theme 1: Construction Management and Process Theme 2: Materials and Transportation Engineering Theme 3: Geotechnical, Environmental, and Geo-environmental Engineering Theme 4: Sustainability, Renovation, and Monitoring of Civil InfrastructureThe list of the Sponsors are listed at page 1