IMPROVED EVOLUTIONARY SUPPORT VECTOR MACHINE CLASSIFIER FOR CORONARY ARTERY HEART DISEASE PREDICTION AMONG DIABETIC PATIENTS

Soft computing paves way many applications including medical informatics. Decision support system has gained a major attention that will aid medical practitioners to diagnose diseases. Diabetes mellitus is hereditary disease that might result in major heart disease. This research work aims to propose a soft computing mechanism named Improved Evolutionary Support Vector Machine classifier for CAHD risk prediction among diabetes patients. The attribute selection mechanism is attempted to build with the classifier in order to reduce the misclassification error rate of the conventional support vector machine classifier. Radial basis kernel function is employed in IESVM. IESVM classifier is evaluated through the performance metrics namely sensitivity, specificity, prediction accuracy and Matthews correlation coefficient (MCC) and also compared with existing work and our earlier proposed works

Global ECG Classification by Self-Operational Neural Networks with Feature Injection

Objective: Global (inter-patient) ECG classification for arrhythmia detection over Electrocardiogram (ECG) signal is a challenging task for both humans and machines. The main reason is the significant variations of both normal and arrhythmic ECG patterns among patients. Automating this process with utmost accuracy is, therefore, highly desirable due to the advent of wearable ECG sensors. However, even with numerous deep learning approaches proposed recently, there is still a notable gap in the performance of global and patient-specific ECG classification performances. This study proposes a novel approach to narrow this gap and propose a real-time solution with shallow and compact 1D Self-Organized Operational Neural Networks (Self-ONNs). Methods: In this study, we propose a novel approach for inter-patient ECG classification using a compact 1D Self-ONN by exploiting morphological and timing information in heart cycles. We used 1D Self-ONN layers to automatically learn morphological representations from ECG data, enabling us to capture the shape of the ECG waveform around the R peaks. We further inject temporal features based on RR interval for timing characterization. The classification layers can thus benefit from both temporal and learned features for the final arrhythmia classification. Results: Using the MIT-BIH arrhythmia benchmark database, the proposed method achieves the highest classification performance ever achieved, i.e., 99.21% precision, 99.10% recall, and 99.15% F1-score for normal (N) segments; 82.19% precision, 82.50% recall, and 82.34% F1-score for the supra-ventricular ectopic beat (SVEBs); and finally, 94.41% precision, 96.10% recall, and 95.2% F1-score for the ventricular-ectopic beats (VEBs)

A framework for cardiac arrhythmia detection from IoT-based ECGs

Cardiac arrhythmia has been identified as a type of cardiovascular diseases (CVDs) that causes approximately 12% of all deaths globally. The development of Internet-of-Things has spawned novel ways for heart monitoring but also presented new challenges for manual arrhythmia detection. An automated method is highly demanded to provide support for physicians. Current attempts for automatic arrhythmia detection can roughly be divided as feature-engineering based and deep-learning based methods. Most of the feature-engineering based methods are suffering from adopting single classifier and use fixed features for classifying all five types of heartbeats. This introduces difficulties in identification of the problematic heartbeats and limits the overall classification performance. The deep-learning based methods are usually not evaluated in a realistic manner and report overoptimistic results which may hide potential limitations of the models. Moreover, the lack of consideration of frequency patterns and the heart rhythms can also limit the model performance. To fill in the gaps, we propose a framework for arrhythmia detection from IoT-based ECGs. The framework consists of two modules: a data cleaning module and a heartbeat classification module. Specifically, we propose two solutions for the heartbeat classification task, namely Dynamic Heartbeat Classification with Adjusted Features (DHCAF) and Multi-channel Heartbeat Convolution Neural Network (MCHCNN). DHCAF is a feature-engineering based approach, in which we introduce dynamic ensemble selection (DES) technique and develop a result regulator to improve classification performance. MCHCNN is deep-learning based solution that performs multi-channel convolutions to capture both temporal and frequency patterns from heartbeat to assist the classification. We evaluate the proposed framework with DHCAF and with MCHCNN on the well-known MIT-BIH-AR database, respectively. The results reported in this paper have proven the effectiveness of our framework

Exploring ECG Signal Analysis Techniques for Arrhythmia Detection: A Review

The heart holds paramount importance in the human body as it serves the crucial function of supplying blood and nutrients to various organs. Thus, maintaining its health is imperative. Arrhythmia, a heart disorder, arises when the heart's rhythm becomes irregular. Electrocardiogram (ECG) signals are commonly utilized for analyzing arrhythmia due to their simplicity and cost-effectiveness. The peaks observed in ECG graphs, particularly the R peak, are indicative of heart conditions, facilitating arrhythmia diagnosis. Arrhythmia is broadly categorized into Tachycardia and Bradycardia for identification purposes. This paper explores diverse techniques such as Deep Convolutional Neural Networks (CNNs), Long Short-Term Memory (LSTM), Support Vector Machines (SVM), Neural Network (NN) classifiers, as well as Wavelet and Time–Frequency Transform (TQWT), which have been employed over the past decade for arrhythmia detection using various datasets. The study delves into the analysis of arrhythmia classification on ECG datasets, highlighting the effectiveness of data preprocessing, feature extraction, and classification techniques in achieving superior performance in classifying ECG signals for arrhythmia detection

Global ECG Classification by Self-Operational Neural Networks with Feature Injection

Objective: Global (inter-patient) ECG classification for arrhythmia detection over Electrocardiogram (ECG) signal is a challenging task for both humans and machines. Automating this process with utmost accuracy is, therefore, highly desirable due to the advent of wearable ECG sensors. However, even with numerous deep learning approaches proposed recently, there is still a notable gap in the performance of global and patient-specific ECG classification performance.  Methods: In this study, we propose a novel approach for inter-patient ECG classification using a compact 1D Self-ONN by exploiting morphological and timing information in heart cycles. We used 1D Self-ONN layers to automatically learn morphological representations from ECG data, enabling us to capture the shape of the ECG waveform around the R peaks. We further inject temporal features based on RR interval for timing characterization. The classification layers can thus benefit from both temporal and learned features for the final arrhythmia classification. Results: Using the MIT-BIH arrhythmia benchmark database, the proposed method achieves the highest classification performance ever achieved, i.e., 99.21% precision, 99.10% recall, and 99.15% F1-score for normal (N) segments; 82.19% precision, 82.50% recall, and 82.34% F1-score for the supra-ventricular ectopic beat (SVEBs); and finally, 94.41% precision, 96.10% recall, and 95.2% F1-score for the ventricular-ectopic beats (VEBs). Significance:  As a pioneer application, the results show that compact and shallow 1D Self-ONNs with the feature injection can surpass all state-of-the-art deep models with a significant margin and with minimal computational complexity. Conclusion: This study has demonstrated that using a compact and superior network model, a global ECG classification can still be achieved with an elegant performance level even when no patient-specific information is used.publishedVersionPeer reviewe

HEART RHYTHM CLASSIFICATION FROM STATIC AND ECG TIME-SERIES DATA USING HYBRID MULTIMODAL DEEP LEARNING

Cardiovascular arrhythmia diseases are considered as the most common diseases that cause death around the world. Abnormal arrhythmia diseases can be identified by analyzing heart rhythm using an electrocardiogram (ECG). However, this analysis is done manually by cardiologists, which may be subjective and susceptible to different cardiologist observations and experiences, as well as to noise and irregularities in those signals. This can lead to misdiagnosis. Motivated by this challenge, an automated heart rhythm diagnosis approach from ECG signals using Deep Learning has been proposed. In order to achieve this goal, three research problems have been addressed. First, recognize the role of each single-lead of a 12-lead ECG to classify heart rhythms. Second, understanding the importance of static data (e.g., demographics and clinical profile) in classifying heart rhythms. Third, realizing whether the static data can be combined with the ECG time series data for better classification performance. In this thesis, different deep learning models have been proposed to address these problems and satisfactory results are achieved. Therefore, using this knowledge, an effective hybrid deep learning model to classify heart rhythms has been proposed. As per knowledge obtained from relevant literature, this is the first work to identify the importance of individual lead and combined lead as well as the importance of combining static data with ECG time series data in classifying heart rhythms. Extensive experiments have been performed to evaluate this algorithm on a 12-lead ECG database that contains data from more than 10,000 individual subjects and obtained a high average of accuracy (up to 98.7%) and F1-measure (up to 98.7%). Moreover, in this thesis, the distribution of heart rhythms from the database based on heart rhythm type, gender, and age group have been analyzed, which will be valuable for further improvement of classification performance. This study will provide valuable insights and will prove to be an effective tool in automated heart rhythm classification and will assist cardiologists in effectively and accurately diagnosing heart disease

ECG Recurrence Plot-Based Arrhythmia Classification Using Two-Dimensional Deep Residual CNN Features

Data Availability Statement: This study utilizes the publicly available dataset, from https:// physionet.org, accessed on 22 June 2020.Copyright: © 2022 by the authors. In this paper, an effective electrocardiogram (ECG) recurrence plot (RP)-based arrhythmia classification algorithm that can be implemented in portable devices is presented. Public databases from PhysioNet were used to conduct this study including the MIT-BIH Atrial Fibrillation Database, the MIT-BIH Arrhythmia Database, the MIT-BIH Malignant Ventricular Ectopy Database, and the Creighton University Ventricular Tachyarrhythmia Database. ECG time series were segmented and converted using an RP, and two-dimensional images were used as inputs to the CNN classifiers. In this study, two-stage classification is proposed to improve the accuracy. The ResNet-18 architecture was applied to detect ventricular fibrillation (VF) and noise during the first stage, whereas normal, atrial fibrillation, premature atrial contraction, and premature ventricular contractions were de-tected using ResNet-50 in the second stage. The method was evaluated using 5-fold cross-validation which improved the results when compared to previous studies, achieving first and second stage average accuracies of 97.21% and 98.36%, sensitivities of 96.49% and 97.92%, positive predictive values of 95.54% and 98.20%, and F1-scores of 95.96% and 98.05%, respectively. Furthermore, a 5-fold improvement in the memory requirement was achieved when compared with a previous study, making this classifier feasible for use in resource-constricted environments such as portable devices. Even though the method is successful, first stage training requires combining four different arrhyth-mia types into one label (other), which generates more data for the other category than for VF and noise, thus creating a data imbalance that affects the first stage performance.Ministry of Science and Technology, Taiwan (grant number: MOST 110-2221-E-155-004-MY2)