64,460 research outputs found

    SkILL - a Stochastic Inductive Logic Learner

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    Probabilistic Inductive Logic Programming (PILP) is a rel- atively unexplored area of Statistical Relational Learning which extends classic Inductive Logic Programming (ILP). This work introduces SkILL, a Stochastic Inductive Logic Learner, which takes probabilistic annotated data and produces First Order Logic theories. Data in several domains such as medicine and bioinformatics have an inherent degree of uncer- tainty, that can be used to produce models closer to reality. SkILL can not only use this type of probabilistic data to extract non-trivial knowl- edge from databases, but it also addresses efficiency issues by introducing a novel, efficient and effective search strategy to guide the search in PILP environments. The capabilities of SkILL are demonstrated in three dif- ferent datasets: (i) a synthetic toy example used to validate the system, (ii) a probabilistic adaptation of a well-known biological metabolism ap- plication, and (iii) a real world medical dataset in the breast cancer domain. Results show that SkILL can perform as well as a deterministic ILP learner, while also being able to incorporate probabilistic knowledge that would otherwise not be considered

    Inductive queries for a drug designing robot scientist

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    It is increasingly clear that machine learning algorithms need to be integrated in an iterative scientific discovery loop, in which data is queried repeatedly by means of inductive queries and where the computer provides guidance to the experiments that are being performed. In this chapter, we summarise several key challenges in achieving this integration of machine learning and data mining algorithms in methods for the discovery of Quantitative Structure Activity Relationships (QSARs). We introduce the concept of a robot scientist, in which all steps of the discovery process are automated; we discuss the representation of molecular data such that knowledge discovery tools can analyse it, and we discuss the adaptation of machine learning and data mining algorithms to guide QSAR experiments

    Tupleware: Redefining Modern Analytics

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    There is a fundamental discrepancy between the targeted and actual users of current analytics frameworks. Most systems are designed for the data and infrastructure of the Googles and Facebooks of the world---petabytes of data distributed across large cloud deployments consisting of thousands of cheap commodity machines. Yet, the vast majority of users operate clusters ranging from a few to a few dozen nodes, analyze relatively small datasets of up to a few terabytes, and perform primarily compute-intensive operations. Targeting these users fundamentally changes the way we should build analytics systems. This paper describes the design of Tupleware, a new system specifically aimed at the challenges faced by the typical user. Tupleware's architecture brings together ideas from the database, compiler, and programming languages communities to create a powerful end-to-end solution for data analysis. We propose novel techniques that consider the data, computations, and hardware together to achieve maximum performance on a case-by-case basis. Our experimental evaluation quantifies the impact of our novel techniques and shows orders of magnitude performance improvement over alternative systems
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