5,262 research outputs found

    Beam lead technology

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    Beam lead technology for microcircuit interconnections with applications to metallization, passivation, and bondin

    GluN2A NMDA Receptor Enhancement Improves Brain Oscillations, Synchrony, and Cognitive Functions in Dravet Syndrome and Alzheimer's Disease Models.

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    NMDA receptors (NMDARs) play subunit-specific roles in synaptic function and are implicated in neuropsychiatric and neurodegenerative disorders. However, the in vivo consequences and therapeutic potential of pharmacologically enhancing NMDAR function via allosteric modulation are largely unknown. We examine the in vivo effects of GNE-0723, a positive allosteric modulator of GluN2A-subunit-containing NMDARs, on brain network and cognitive functions in mouse models of Dravet syndrome (DS) and Alzheimer's disease (AD). GNE-0723 use dependently potentiates synaptic NMDA receptor currents and reduces brain oscillation power with a predominant effect on low-frequency (12-20 Hz) oscillations. Interestingly, DS and AD mouse models display aberrant low-frequency oscillatory power that is tightly correlated with network hypersynchrony. GNE-0723 treatment reduces aberrant low-frequency oscillations and epileptiform discharges and improves cognitive functions in DS and AD mouse models. GluN2A-subunit-containing NMDAR enhancers may have therapeutic benefits in brain disorders with network hypersynchrony and cognitive impairments

    Instrumentation for observation of high frequency signals in the scanning electron microscope

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    SIGLELD:D48882/84 / BLDSC - British Library Document Supply CentreGBUnited Kingdo

    Satellite fixed communications service: A forecast of potential domestic demand through the year 2000. Volume 3: Appendices

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    Voice applications, data applications, video applications, impacted baseline forecasts, market distribution model, net long haul forecasts, trunking earth station definition and costs, trunking space segment cost, trunking entrance/exit links, trunking network costs and crossover distances with terrestrial tariffs, net addressable forecasts, capacity requirements, improving spectrum utilization, satellite system market development, and the 30/20 net accessible market are considered

    The 30/20 GHz flight experiment system, phase 2. Volume 2: Experiment system description

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    A detailed technical description of the 30/20 GHz flight experiment system is presented. The overall communication system is described with performance analyses, communication operations, and experiment plans. Hardware descriptions of the payload are given with the tradeoff studies that led to the final design. The spacecraft bus which carries the payload is discussed and its interface with the launch vehicle system is described. Finally, the hardwares and the operations of the terrestrial segment are presented

    Millimeter-Wave Components and Antennas for Spatial and Polarization Diversity using PRGW Technology

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    The evolution of the wireless communication systems to the future generation is accompanied by a huge improvement in the system performance through providing a high data rate with low latency. These systems require access to millimeter wave (mmWave) bands, which offer several advantages such as physically smaller components and much wider bandwidthcomparedtomicrowavefrequencies. However, mmWavecomponentsstillneed a significant improvement to follow the rapid variations in future technologies. Although mmWave frequencies can carry more data, they are limited in terms of their penetration capabilities and their coverage range. Moreover, these frequencies avoid deploying traditional guiding technologies such as microstrip lines due to high radiation and material losses. Hence, utilizing new guiding structure techniques such as Printed Ridge Gap Waveguide (PRGW) is essential in future mmWave systems implementation. ThemainpurposeofthisthesisistodesignmmWavecomponents,antennasubsystems and utilize both in beam switching systems. The major mmWave components addressed in this thesis are hybrid coupler, crossover, and differential power divider where the host guidingstructureisthePRGW.Inaddition,variousdesignsfordifferentialfeedingPRGW antennas and antenna arrays are presented featuring wide bandwidth and high gain in mmWave band. Moreover, the integration of both the proposed components and the featured antennas is introduced. This can be considered as a significant step toward the requirements fulfillment of today's advanced communication systems enabling both space and polarization diversity. The proposed components are designed to meet the future ever-increasing consumer experience and technical requirements such as low loss, compact size, and low-cost fabrication. This directed the presented research to have a contribution into three major parts. The first part highlights the feeding structures, where mmWave PRGW directional couplers and differential feeding power divider are designed and validated. These components are among the most important passive elements of microwave circuits used in antennabeam-switchingnetworks. Different3-dBquadraturehybridcouplersandcrossover prototypes are proposed, featured with a compact size and a wide bandwidth beyond 10 % at 30 GHz. In the second part, a beam switching network implemented using hybrid couplers is presented. The proposed beam switching network is a 4 × 4 PRGW Butler matrix that used to feed a Magneto-electric (ME) dipole antenna array. As a result, a 2-D scanning antenna array with a compact size, wide bandwidth, and high radiation efficiency larger than84%isachieved. Furthergainenhancementof5dBiisachievedthroughdeployinga hybridgainenhancementtechniqueincludingAMCmushroomshapesaroundtheantenna array with a dielectric superstrate located in the broadside direction. The proposed scanning antenna array can be considered as a step toward the desired improvement in the data rate and coverage through enabling the space diversity for the communication link. The final activity is related to the development of high-gain wide-band mmWave antenna arrays for potential use in future mmWave applications. The first proposed configuration is a differential feeding circular polarized aperture antenna array implemented with PRGW technology. Differential feeding antenna designs offer more advantages than single- ended antennas for mmWave communications as they are easy to be integrated with differential mmWave monolithic ICs that have high common-mode rejection ratio providing an immunity of the environmental noise. The proposed differential feeding antenna array is designed and fabricated, which featured with a stable high gain and a high radiation efficiency over a wide bandwidth. Another proposed configuration is a dualpolarized ME-dipole PRGW antenna array for mmWave wireless communication. Dual polarizationisconsideredoneofthemostimportantantennasolutionsthatcansavecosts and space for modern communication systems. In addition, it is an effective strategy for multiple-input and multiple-output systems that can reduce the size of multiple antennas systems by utilizing extra orthogonal polarization. The proposed dual- polarized antenna array is designed to achieve a stable gain of 15 ± 1 dBi with low cross- polarization less than -30 dB over a wide frequency range of 20 % at 30 GHz

    Index to NASA tech briefs, 1971

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    The entries are listed by category, subject, author, originating source, source number/Tech Brief number, and Tech Brief number/source number. There are 528 entries

    Low Loss Plasmon-Assisted Integrated Photonics

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    Photonic integrated circuits (PICs), semiconductor chips with both photonic and electronic elements, are seeing rapid development and have the potential to transform several industries, such as autonomous driving, computing, telecommunication and quantum networks. However, realization and wide adoption of PICs across the various fields faces a key challenge – soze disparity between electronic (~0.01 um) and photonic components (~100’s of um). Plasmonics, a technology which confines light to the interface of metals and dielectrics, has a potential to address challenges. In particular, it has been shown to led to smaller devices (~10 um or less), enabling higher density optical circuits and devices on-chip. However, the technology is limited by quite extraordinarily high off-state transmission, wherein ~10% of an input signal makes it out of the device. This is simply too high to be practical. This thesis addresses this size disparity, while maintaining high speeds (100’s of GHz), low losses (\u3c 1dB) and high energy efficiency (~ 100 fJ/bit), through the concept of plasmon-assisted devices. The plasmon-assisted design philosophy is based on engaging and disengaging the lossy plasmonic component based on when active modulation is needed. As will be shown, the use of the plasmon-assisted approach generates proposed devices that have the potential to exhibit record performance, significantly elevating the capabilities of integrated photonic devices while greatly reducing the size disparity. For example, the all-oxide modulator can exhibit resistive-capacitive (RC) limited speeds of up to 333 GHz with a sub 0.2 dB insertion loss (IL), while the hybrid polymer-based modulator can exhibit RC limited speeds of 700 GHz but with narrow linewidth. The NOEM based devices can operate with record low energy consumption, down to a few 100 aJ/bit. In addition, this record-breaking performance can be achieved with device that are less than 40 um2 in size
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