A computer aided analysis scheme for detecting epileptic seizure from EEG data

This paper presents a computer aided analysis system for detecting epileptic seizure from electroencephalogram (EEG) signal data. As EEG recordings contain a vast amount of data, which is heterogeneous with respect to a time-period, we intend to introduce a clustering technique to discover different groups of data according to similarities or dissimilarities among the patterns. In the proposed methodology, we use K-means clustering for partitioning each category EEG data set (e.g. healthy; epileptic seizure) into several clusters and then extract some representative characteristics from each cluster. Subsequently, we integrate all the features from all the clusters in one feature set and then evaluate that feature set by three well-known machine learning methods: Support Vector Machine (SVM), Naive bayes and Logistic regression. The proposed method is tested by a publicly available benchmark database: ‘Epileptic EEG database’. The experimental results show that the proposed scheme with SVM classifier yields overall accuracy of 100% for classifying healthy vs epileptic seizure signals and outperforms all the recent reported existing methods in the literature. The major finding of this research is that the proposed K-means clustering based approach has an ability to efficiently handle EEG data for the detection of epileptic seizure

Performance Analysis of Deep-Learning and Explainable AI Techniques for Detecting and Predicting Epileptic Seizures

Epilepsy is one of the most common neurological diseases globally. Notably, people in low to middle-income nations could not get proper epilepsy treatment due to the cost and availability of medical infrastructure. The risk of sudden unpredicted death in Epilepsy is considerably high. Medical statistics reveal that people with Epilepsy die more prematurely than those without the disease. Early and accurately diagnosing diseases in the medical field is challenging due to the complex disease patterns and the need for time-sensitive medical responses to the patients. Even though numerous machine learning and advanced deep learning techniques have been employed for the seizure stages classification and prediction, understanding the causes behind the decision is difficult, termed a black box problem. Hence, doctors and patients are confronted with the black box decision-making to initiate the appropriate treatment and understand the disease patterns respectively. Owing to the scarcity of epileptic Electroencephalography (EEG) data, training the deep learning model with diversified epilepsy knowledge is still critical. Explainable Artificial intelligence has become a potential solution to provide the explanation and result interpretation of the learning models. By applying the explainable AI, there is a higher possibility of examining the features that influence the decision-making that either the patient recorded from epileptic or non-epileptic EEG signals. This paper reviews the various deep learning and Explainable AI techniques used for detecting and predicting epileptic seizures  using EEG data. It provides a comparative analysis of the different techniques based on their performance

Edge-based Compression and Classification for Smart Healthcare Systems: Concept, Implementation and Evaluation

Smart healthcare systems require recording, transmitting and processing large volumes of multimodal medical data generated from different types of sensors and medical devices, which is challenging and may turn some of the remote health monitoring applications impractical. Moving computational intelligence to the net- work edge is a promising approach for providing efficient and convenient ways for continuous-remote monitoring. Implementing efficient edge-based classification and data reduction techniques are of paramount importance to enable smart health- care systems with efficient real-time and cost-effective remote monitoring. Thus, we present our vision of leveraging edge computing to monitor, process, and make au- tonomous decisions for smart health applications. In particular, we present and im- plement an accurate and lightweight classification mechanism that, leveraging some time-domain features extracted from the vital signs, allows for a reliable seizures detection at the network edge with precise classification accuracy and low com- putational requirement. We then propose and implement a selective data transfer scheme, which opts for the most convenient way for data transmission depending on the detected patient’s conditions. In addition to that, we propose a reliable energy-efficient emergency notification system for epileptic seizure detection, based on conceptual learning and fuzzy classification. Our experimental results assess the performance of the proposed system in terms of data reduction, classification accuracy, battery lifetime, and transmission delay. We show the effectiveness of our system and its ability to outperform conventional remote monitoring systems that ignore data processing at the edge by: (i) achieving 98.3% classification accuracy for seizures detection, (ii) extending battery lifetime by 60%, and (iii) decreasing average transmission delay by 90%

Integrated Machine Learning Approaches to Improve Classification performance and Feature Extraction Process for EEG Dataset

Epileptic seizure or epilepsy is a chronic neurological disorder that occurs due to brain neurons\u27 abnormal activities and has affected approximately 50 million people worldwide. Epilepsy can affect patients’ health and lead to life-threatening emergencies. Early detection of epilepsy is highly effective in avoiding seizures by intervening in treatment. The electroencephalogram (EEG) signal, which contains valuable information of electrical activity in the brain, is a standard neuroimaging tool used by clinicians to monitor and diagnose epilepsy. Visually inspecting the EEG signal is an expensive, tedious, and error-prone practice. Moreover, the result varies with different neurophysiologists for an identical reading. Thus, automatically classifying epilepsy into different epileptic states with a high accuracy rate is an urgent requirement and has long been investigated. This PhD thesis contributes to the epileptic seizure detection problem using Machine Learning (ML) techniques. Machine learning algorithms have been implemented to automatically classifying epilepsy from EEG data. Imbalance class distribution problems and effective feature extraction from the EEG signals are the two major concerns towards effectively and efficiently applying machine learning algorithms for epilepsy classification. The algorithms exhibit biased results towards the majority class when classes are imbalanced, while effective feature extraction can improve classification performance. In this thesis, we presented three different novel frameworks to effectively classify epileptic states while addressing the above issues. Firstly, a deep neural network-based framework exploring different sampling techniques was proposed where both traditional and state-of-the-art sampling techniques were experimented with and evaluated for their capability of improving the imbalance ratio and classification performance. Secondly, a novel integrated machine learning-based framework was proposed to effectively learn from EEG imbalanced data leveraging the Principal Component Analysis method to extract high- and low-variant principal components, which are empirically customized for the imbalanced data classification. This study showed that principal components associated with low variances can capture implicit patterns of the minority class of a dataset. Next, we proposed a novel framework to effectively classify epilepsy leveraging summary statistics analysis of window-based features of EEG signals. The framework first denoised the signals using power spectrum density analysis and replaced outliers with k-NN imputer. Next, window level features were extracted from statistical, temporal, and spectral domains. Basic summary statistics are then computed from the extracted features to feed into different machine learning classifiers. An optimal set of features are selected leveraging variance thresholding and dropping correlated features before feeding the features for classification. Finally, we applied traditional machine learning classifiers such as Support Vector Machine, Decision Tree, Random Forest, and k-Nearest Neighbors along with Deep Neural Networks to classify epilepsy. We experimented the frameworks with a benchmark dataset through rigorous experimental settings and displayed the effectiveness of the proposed frameworks in terms of accuracy, precision, recall, and F-beta score

Automatic identification of epileptic and background EEG signals using frequency domain parameters

The analysis of electroencephalograms continues to be a problem due to our limited understanding of the signal origin. This limited understanding leads to ill-defined models, which in turn make it hard to design effective evaluation methods. Despite these shortcomings, electroencephalogram analysis is a valuable tool in the evaluation of neurological disorders and the evaluation of overall cerebral activity. We compared different model based power spectral density estimation methods and different classification methods. Specifically, we used the autoregressive moving average as well as from Yule-Walker and Burg's methods, to extract the power density spectrum from representative signal samples. Local maxima and minima were detected from these spectra. In this paper, the locations of these extrema are used as input to different classifiers. The three classifiers we used were: Gaussian mixture model, artificial neural network, and support vector machine. The classification results are documented with confusion matrices and compared with receiver operating characteristic curves. We found that Burg's method for spectrum estimation together with a support vector machine classifier yields the best classification results. This combination reaches a classification rate of 93.33%, the sensitivity is 98.33% and the specificy is 96.67%