Considerations for an Extended Framework for Interactive Epoch-Era Analysis

AbstractEpoch-Era Analysis (EEA) is a framework that supports narrative and computational scenario planning and analysis for both short run and long run futures. Currently EEA is being applied to frame problems faced by the DoD's Engineered Resilient Systems (ERS) efforts. Because of the large amount of data that must be analyzed when extending EEA to large-scale problems, such as those posed by DoD, a “big data” problem is introduced. This motivates the need for extensions to EEA methods that overcome the computational and human cognition issues that arise as a result. The research presented here describes exploratory development of Interactive Epoch-Era Analysis (IEEA) methods, including human interface and reasoning considerations for epoch and era characterizations, as well as single and multi- epoch and era analyses. Visualization techniques and methods for mitigating computational resource restrictions that facilitate improved decision-making are also presented

Exploratory of society

A huge flow of quantitative social, demographic and behavioral data is becoming available that traces the activities and interactions of individuals, social patterns, transportation infrastructures and travel fluxes. This has caused, together with innovative computational techniques and methods for modeling social actions in hybrid (natural and artificial) societies, a qualitative change in the ways we model socio-technical systems. For the first time, society can be studied in a comprehensive fashion that addresses social and behavioral complexity. In other words we are in the position to envision the development of large data and computational cyber infrastructure defining an exploratory of society that provides quantitative anticipatory, explanatory and scenario analysis capabilities ranging from emerging infectious disease to conflict and crime surges. The goal of the exploratory of society is to provide the basic infrastructure embedding the framework of tools and knowledge needed for the design of forecast/anticipatory/crisis management approaches to socio technical systems, supporting future decision making procedures by accelerating the scientific cycle that goes from data generation to predictions. Graphical abstrac

A CyberGIS Integration and Computation Framework for High‐Resolution Continental‐Scale Flood Inundation Mapping

We present a Digital Elevation Model (DEM)-based hydrologic analysis methodology for continental flood inundation mapping (CFIM), implemented as a cyberGIS scientific workflow in which a 1/3rd arc-second (10m) Height Above Nearest Drainage (HAND) raster data for the conterminous U.S. (CONUS) was computed and employed for subsequent inundation mapping. A cyberGIS framework was developed to enable spatiotemporal integration and scalable computing of the entire inundation mapping process on a hybrid supercomputing architecture. The first 1/3rd arc-second CONUS HAND raster dataset was computed in 1.5 days on the CyberGIS ROGER supercomputer. The inundation mapping process developed in our exploratory study couples HAND with National Water Model (NWM) forecast data to enable near real-time inundation forecasts for CONUS. The computational performance of HAND and the inundation mapping process was profiled to gain insights into the computational characteristics in high-performance parallel computing scenarios. The establishment of the CFIM computational framework has broad and significant research implications that may lead to further development and improvement of flood inundation mapping methodologies

An economic and financial exploratory

This paper describes the vision of a European Exploratory for economics and finance using an interdisciplinary consortium of economists, natural scientists, computer scientists and engineers, who will combine their expertise to address the enormous challenges of the 21st century. This Academic Public facility is intended for economic modelling, investigating all aspects of risk and stability, improving financial technology, and evaluating proposed regulatory and taxation changes. The European Exploratory for economics and finance will be constituted as a network of infrastructure, observatories, data repositories, services and facilities and will foster the creation of a new cross-disciplinary research community of social scientists, complexity scientists and computing (ICT) scientists to collaborate in investigating major issues in economics and finance. It is also considered a cradle for training and collaboration with the private sector to spur spin-offs and job creations in Europe in the finance and economic sectors. The Exploratory will allow Social Scientists and Regulators as well as Policy Makers and the private sector to conduct realistic investigations with real economic, financial and social data. The Exploratory will (i) continuously monitor and evaluate the status of the economies of countries in their various components, (ii) use, extend and develop a large variety of methods including data mining, process mining, computational and artificial intelligence and every other computer and complex science techniques coupled with economic theory and econometric, and (iii) provide the framework and infrastructure to perform what-if analysis, scenario evaluations and computational, laboratory, field and web experiments to inform decision makers and help develop innovative policy, market and regulation designs. Graphical abstrac

Democratized image analytics by visual programming through integration of deep models and small-scale machine learning

Analysis of biomedical images requires computational expertize that are uncommon among biomedical scientists. Deep learning approaches for image analysis provide an opportunity to develop user-friendly tools for exploratory data analysis. Here, we use the visual programming toolbox Orange (http://orange.biolab.si) to simplify image analysis by integrating deep-learning embedding, machine learning procedures, and data visualization. Orange supports the construction of data analysis workflows by assembling components for data preprocessing, visualization, and modeling. We equipped Orange with components that use pre-trained deep convolutional networks to profile images with vectors of features. These vectors are used in image clustering and classification in a framework that enables mining of image sets for both novel and experienced users. We demonstrate the utility of the tool in image analysis of progenitor cells in mouse bone healing, identification of developmental competence in mouse oocytes, subcellular protein localization in yeast, and developmental morphology of social amoebae

Assessment of statistical methods from single cell, bulk RNA-seq, and metagenomics applied to microbiome data

BackgroundThe correct identification of differentially abundant microbial taxa between experimental conditions is a methodological and computational challenge. Recent work has produced methods to deal with the high sparsity and compositionality characteristic of microbiome data, but independent benchmarks comparing these to alternatives developed for RNA-seq data analysis are lacking.ResultsWe compare methods developed for single-cell and bulk RNA-seq, and specifically for microbiome data, in terms of suitability of distributional assumptions, ability to control false discoveries, concordance, power, and correct identification of differentially abundant genera. We benchmark these methods using 100 manually curated datasets from 16S and whole metagenome shotgun sequencing.ConclusionsThe multivariate and compositional methods developed specifically for microbiome analysis did not outperform univariate methods developed for differential expression analysis of RNA-seq data. We recommend a careful exploratory data analysis prior to application of any inferential model and we present a framework to help scientists make an informed choice of analysis methods in a dataset-specific manner

Power to the Teachers:An Exploratory Review on Artificial Intelligence in Education

This exploratory review attempted to gather evidence from the literature by shedding light on the emerging phenomenon of conceptualising the impact of artificial intelligence in education. The review utilised the PRISMA framework to review the analysis and synthesis process encompassing the search, screening, coding, and data analysis strategy of 141 items included in the corpus. Key findings extracted from the review incorporate a taxonomy of artificial intelligence applications with associated teaching and learning practice and a framework for helping teachers to develop and self-reflect on the skills and capabilities envisioned for employing artificial intelligence in education. Implications for ethical use and a set of propositions for enacting teaching and learning using artificial intelligence are demarcated. The findings of this review contribute to developing a better understanding of how artificial intelligence may enhance teachers’ roles as catalysts in designing, visualising, and orchestrating AI-enabled teaching and learning, and this will, in turn, help to proliferate AI-systems that render computational representations based on meaningful data-driven inferences of the pedagogy, domain, and learner models