A randomized iterated greedy algorithm for the founder sequence reconstruction problem

The problem of inferring ancestral genetic information in terms of a set of founders of a given population arises in various biological contexts. In optimization terms, this problem can be formulated as a combinatorial string problem. The main problem of existing techniques, both exact and heuristic, is that their time complexity scales exponentially, which makes them impractical for solving large-scale instances. Basing our work on previous ideas outlined in [1], we developed a randomized iterated greedy algorithm that is able to provide good solutions in a short time span. The experimental evaluation shows that our algorithm is currently the best approximate technique, especially when large problem instances are concerned.Peer ReviewedPostprint (published version

A randomized iterated greedy algorithm for the founder sequence reconstruction problem

The problem of inferring ancestral genetic information in terms of a set of founders of a given population arises in various biological contexts. In optimization terms, this problem can be formulated as a combinatorial string problem. The main problem of existing techniques, both exact and heuristic, is that their time complexity scales exponentially, which makes them impractical for solving large-scale instances. Basing our work on previous ideas outlined in [1], we developed a randomized iterated greedy algorithm that is able to provide good solutions in a short time span. The experimental evaluation shows that our algorithm is currently the best approximate technique, especially when large problem instances are concerned.Peer Reviewe

Critérios de identificação e delimitação de assentamentos rurais: aplicação de um algoritmo como sistema de apoio à decisão no planeamento rural na Galiza, Espanha

A investigação desenvolvida na tese de doutoramento trata de definir critérios para delimitar assentamentos rurais sendo a área de estudo a Galiza, Comunidade Autónoma de Espanha localizada a NO de Espanha. O documento divide-se em cinco capítulos. Ao longo do século XX as zonas rurais em diversas regiões do mundo, na Europa em especial, passaram por processos que afectaram o seu desenvolvimento. Devido a dinâmicas socioeconómicas, demográficas e a processos de urbanização, os espaços rurais têm sofrido alterações nas suas estruturas edificadas e produtivas. Assim, delimitar uma área de assentamento é uma tarefa complexa, portanto a sua delimitação deve ser rigorosa e atender a aspectos relevantes da caracterização do espaço rural