Thin-Film PZT based Multi-Channel Acoustic MEMS Transducer for Cochlear Implant Applications

AuthorThis paper presents a multi-channel acoustic transducer that works within the audible frequency range (250-5500 Hz) and mimics the operation of the cochlea by filtering incoming sound. The transducer is composed of eight thin film piezoelectric cantilever beams with different resonance frequencies. The transducer is well suited to be implanted in middle ear cavity with an active volume of 5 mm × 5 mm × 0.62 mm and mass of 4.8 mg. Resonance frequencies and piezoelectric outputs of the beams are modeled with Finite Element Method (FEM). Vibration experiments showed that the transducer is capable of generating up to 139.36 mVpp under 0.1 g excitation. Test results are consistent with the FEM model on frequency (97%) and output voltage (89%) values. Device was further tested with acoustic excitation on an artificial tympanic membrane and flexible substrate. Under acoustic excitation, 50.7 mVpp output voltage generated under 100 dB Sound Pressure Level (SPL). Output voltages observed in acoustical and mechanical characterizations are the highest values reported to the best of our knowledge. Finally, to assess the feasibility of the transducer in daily sound levels, it was excited with a speech sample and output signal was recovered. Time-domain waveforms of the recorded and recovered signals showed close patterns

Passive and active middle ear implants

Besides eradication of chronic middle ear disease, the reconstruction of the sound conduction apparatus is a major goal of modern ear microsurgery. The material of choice in cases of partial ossicular replacement prosthesis is the autogenous ossicle. In the event of more extensive destruction of the ossicular chain diverse alloplastic materials, e.g. metals, ceramics, plastics or composits are used for total reconstruction. Their specialised role in conducting sound energy within a half-open implant bed sets high demands on the biocompatibility as well as the acoustic-mechanic properties of the prosthesis. Recently, sophisticated titanium middle ear implants allowing individual adaptation to anatomical variations are widely used for this procedure. However, despite modern developments, hearing restoration with passive implants often faces its limitations due to tubal-middle-ear dysfunction. Here, implantable hearing aids, successfully used in cases of sensorineural hearing loss, offer a promising alternative. This article reviews the actual state of affairs of passive and active middle ear implants

MEMS Transducer for Hearing Aid Device

A study of implantable middle ear MEMS piezoelectric transducer for hearing aids was developed. The physical vibration deflection at the tip of the transducer is simulated using finite element method. Further, a study of thermoelastic damping effect of four designed MEMS mirrors used as resonators is presented. An optical measurement system based on Mach-Zehnder interferometer i

Ultraminiature Piezoelectric Implantable Acoustic Transducers for Biomedical Applications

Miniature piezoelectric acoustic transducers have been developed for numerous applications. Compared to other transduction mechanisms like capacitive or piezoresistive, piezoelectric transducers do not need direct current (DC) bias voltage and can work directly exposed to fluid. Hence, they are good candidates for biomedical applications that often require the transducer to work in water based fluid. Among all piezoelectric materials, aluminum nitride (AlN) is a great choice for implantable sensors because of the high electrical resistance, low dielectric loss, and biocompatibility for in vivo study. This thesis presents the design, modeling, fabrication, and testing of the AlN acoustic transducers, miniaturized to be implantable for biomedical applications like hearing or cardiovascular devices. To design and model the transducer in air and in water, a 3D finite element analysis (FEA) model was built to study the transducer in a viscous fluid environment. An array of AlN bimorph cantilevers were designed to create a multi-resonance transducer to increase the sensitivity in a broad band frequency range. A two-wafer process using microelectricalmechanical systems (MEMS) techniques was used to fabricate the xylophone transducer with flexible cable. Benchtop testing confirmed the transducer functionality and verified the FEA model experimentally. The transducer was then implanted inside a living cochlea of a guinea pig and tested in vivo. The piezoelectric voltage output from the transducer was measured in response to 80-95 dB sound pressure level (SPL) sinusoidal excitation spanning 1-14 kHz. The phases showed clear acoustic delay. The measured voltage responses were linear and above the noise level. These results demonstrated that the transducer can work as a sensor for a fully implantable cochlear implant. The second generation device, an ultraminiature diaphragm transducer, was designed to be smaller, and yet with an even lower noise floor. The transducer was designed and optimized using a 2D axial-symmetric FEA model for a better figure of merit (FOM), which considered both minimal detectable pressure (MDP) and the diaphragm area. The low-frequency sensitivity was increased significantly, because of the encapsulated back cavity. Because of this merit, cardiovascular applications, which focus on low frequency signals, were also investigated. The diaphragm transducers were fabricated using MEMS techniques. Benchtop tests for both actuating and sensing confirmed the transducer functionality, and verified the design and model experimentally. The transducer had a better FOM than other existing piezoelectric diaphragm transducers, and it had a much lower MDP than the other intracochlear acoustic sensors.PHDMechanical EngineeringUniversity of Michigan, Horace H. Rackham School of Graduate Studieshttps://deepblue.lib.umich.edu/bitstream/2027.42/147673/1/chumingz_1.pd

Audio-Vestibular Neurosensory Prosthetics: Origins, Expanding Indications and Future Directions

Approximately one-third of persons over 65 years are affected by disabling hearing loss. It is estimated that the number of people with disabling hearing loss will grow to 630 million by 2030 and maybe over 900 million by 2050. Deafness has significant consequences on many aspects of an individual’s life, including their socioeconomic status, mental and physical well-being, educational and employment opportunities. When congenital or early in the developmental years, deafness results in a delay or loss of language acquisition. Deafness can result from damage or disease anywhere along the auditory pathway. Hearing prosthetic devices help restore hearing and the use of these devices depends on the degree and type of hearing loss. This chapter will give a brief account of the currently available prosthetic hearing solutions

Analysis and Design of RF Power and Data Link Using Amplitude Modulation of Class-E for a Novel Bone Conduction Implant

This paper presents analysis and design of a radio frequency power and data link for a novel Bone Conduction Implant (BCI) system. Patients with conductive and mixed hearing loss and single-sided deafness can be rehabilitated by bone-anchored hearing aids (BAHA). Whereas the conventional hearing aids transmit sound to the tympanic membrane via air conduction, the BAHA transmits sound via vibrations through the skull directly to the cochlea. It uses a titanium screw that penetrates the skin and needs life-long daily care; it may cause skin infection and redness. The BCI is developed as an alternative to the percutaneous BAHA since it leaves the skin intact. The BCI comprises an external audio processor with a transmitter coil and an implanted unit called the bridging bone conductor with a receiver coil. Using amplitude modulation of the Class-E power amplifier that drives the inductive link, the sound signal is transmitted to the implant through the intact skin. It was found that the BCI can generate enough output force level for candidate patients. Maximum power output of the BCI was designed to occur at 5-mm skin thickness and the variability was within 1.5 dB for 1–8-mm skin thickness variations

Creation of an incus recess for a middle-ear microphone using a drill or laser ablation : a comparison of equivalent noise level and middle ear transfer function

Purpose: Studies have assessed the trauma and change in hearing function from the use of otological drills on the ossicular chain, but not the effects of partial laser ablation of the incus. A study of the effectiveness of a novel middle-ear microphone for a cochlear implant, which required an incus recess for the microphone balltip, provided an opportunity to compare methods and inform a feasibility study of the microphone with patients. Methods: We used laser Doppler vibrometry with an insert earphone and probe microphone in 23 ears from 14 fresh-frozen cadavers to measure the equivalent noise level at the tympanic membrane that would have led to the same stapes velocity as the creation of the incus recess. Results: Drilling on the incus with a diamond burr created peak noise levels equivalent to 125.1–155.0 dB SPL at the tympanic membrane, whilst using the laser generated equivalent noise levels barely above the baseline level. The change in middle ear transfer function following drilling showed greater variability at high frequencies, but the change was not statistically significant in the three frequency bands tested. Conclusions: Whilst drilling resulted in substantially higher equivalent noise, we considered that the recess created by laser ablation was more likely to lead to movement of the microphone balltip, and therefore decrease performance or result in malfunction over time. For patients with greatly reduced residual hearing, the greater consistency from drilling the incus recess may outweigh the potential benefits of hearing preservation with laser ablation

Aktivni slušni implantat srednjega uha Vibrant Soundbridge

The Vibrant Soundbridge represents a new approach to hearing improvement in the form of active implantable middle ear hearing device. Unlike conventional acoustic hearing aids, which increase the volume of sound that goes to the eardrum, the Vibrant Soundbridge bypasses the ear canal and eardrum by directly vibrating the small bones in the middle ear. Because of its design, no portion of the device is placed in the ear canal itself. The Vibrant Soundbridge has been approved by the FDA as a safe and effective treatment option for adults with moderate to severe sensorineural, conductive or mixed hearing losses who desire an alternative to the acoustic hearing aids, for better hearing. The paper presents a review of the active middle ear implant Vibrant Soundbridge, which has been also implanted at the Department of Otorhinolaryngology and Head and Neck Surgery, Sestre milosrdnice University Hospital Center, which is the Referral Center for Cochlear Implantation and Surgery of Hearing Impairment and Deafness of the Ministry of Health, Republic of Croatia.Vibrant Soundbridge (VSB) predstavlja nov pristup poboljšanju oštećenog sluha aktivnim ugradbenim uređajem za srednje uho. Taj uređaj zaobilazi zvukovod i bubnjić, za razliku od standardnih slušnih pomagala kod kojih povećani volumen zvuka ide kroz njih i izaziva direktne vibracije lanca slušnih košćica. Zahvaljujući svom dizajnu nijedan dio VSB-a nije u zvukovodu. VSB je odobrila FDA kao siguran postupak u liječenju odraslih osoba koje imaju zamjedbeno, provodno ili mješovito oštećenje sluha i koje žele čuti bolje nego sa standardnim slušnim pomagalima. Ovaj rad je pregled djelovanja aktivnog ugradbenog implantata srednjega uha VSB-a koji je ugrađen na Klinici za otorinolaringologiju i kirurgiju glave i vrata KBCa Sestre milosrdnice, Referentnom centru Ministarstva zdravlja za kohlearnu implantaciju i kirurgiju nagluhosti i gluhoće

Consensus Statement on Bone Conduction Devices and Active Middle Ear Implants in Conductive and Mixed Hearing Loss

Nowadays, several options are available to treat patients with conductive or mixed hearing loss. Whenever surgical intervention is not possible or contra-indicated, and amplification by a conventional hearing device (e.g., behind-the-ear device) is not feasible, then implantable hearing devices are an indispensable next option. Implantable bone-conduction devices and middle-ear implants have advantages but also limitations concerning complexity/invasiveness of the surgery, medical complications, and effectiveness. To counsel the patient, the clinician should have a good overview of the options with regard to safety and reliability as well as unequivocal technical performance data. The present consensus document is the outcome of an extensive iterative process including ENT specialists, audiologists, health-policy scientists, and representatives/technicians of the main companies in this field. This document should provide a first framework for procedures and technical characterization to enhance effective communication between these stakeholders, improving health care

Consensus Statement on Bone Conduction Devices and Active Middle Ear Implants in Conductive and Mixed Hearing Loss

Nowadays, several options are available to treat patients with conductive or mixed hearing loss. Whenever surgical intervention is not possible or contra-indicated, and amplification by a conventional hearing device (e.g., behind-the-ear device) is not feasible, then implantable hearing devices are an indispensable next option. Implantable bone-conduction devices and middle-ear implants have advantages but also limitations concerning complexity/invasiveness of the surgery, medical complications, and effectiveness. To counsel the patient, the clinician should have a good overview of the options with regard to safety and reliability as well as unequivocal technical performance data. The present consensus document is the outcome of an extensive iterative process including ENT specialists, audiologists, health-policy scientists, and representatives/technicians of the main companies in this field. This document should provide a first framework for procedures and technical characterization to enhance effective communication between these stakeholders, improving health care