Customizable tubular model for n-furcating blood vessels and its application to 3D reconstruction of the cerebrovascular system

Understanding the 3D cerebral vascular network is one of the pressing issues impacting the diagnostics of various systemic disorders and is helpful in clinical therapeutic strategies. Unfortunately, the existing software in the radiological workstation does not meet the expectations of radiologists who require a computerized system for detailed, quantitative analysis of the human cerebrovascular system in 3D and a standardized geometric description of its components. In this study, we show a method that uses 3D image data from magnetic resonance imaging with contrast to create a geometrical reconstruction of the vessels and a parametric description of the reconstructed segments of the vessels. First, the method isolates the vascular system using controlled morphological growing and performs skeleton extraction and optimization. Then, around the optimized skeleton branches, it creates tubular objects optimized for quality and accuracy of matching with the originally isolated vascular data. Finally, it optimizes the joints on n-furcating vessel segments. As a result, the algorithm gives a complete description of shape, position in space, position relative to other segments, and other anatomical structures of each cerebrovascular system segment. Our method is highly customizable and in principle allows reconstructing vascular structures from any 2D or 3D data. The algorithm solves shortcomings of currently available methods including failures to reconstruct the vessel mesh in the proximity of junctions and is free of mesh collisions in high curvature vessels. It also introduces a number of optimizations in the vessel skeletonization leading to a more smooth and more accurate model of the vessel network. We have tested the method on 20 datasets from the public magnetic resonance angiography image database and show that the method allows for repeatable and robust segmentation of the vessel network and allows to compute vascular lateralization indices. Graphical abstract: [Figure not available: see fulltext.]</p

Discretization schemes and numerical approximations of PDE impainting models and a comparative evaluation on novel real world MRI reconstruction applications

While various PDE models are in discussion since the last ten years and are widely applied nowadays in image processing and computer vision tasks, including restoration, filtering, segmentation and object tracking, the perspective adopted in the majority of the relevant reports is the view of applied mathematician, attempting to prove the existence theorems and devise exact numerical methods for solving them. Unfortunately, such solutions are exact for the continuous PDEs but due to the discrete approximations involved in image processing, the results yielded might be quite unsatisfactory. The major contribution of This work is, therefore, to present, from an engineering perspective, the application of PDE models in image processing analysis, from the algorithmic point of view, the discretization and numerical approximation schemes used for solving them. It is of course impossible to tackle all PDE models applied in image processing in this report from the computational point of view. It is, therefore, focused on image impainting PDE models, that is on PDEs, including anisotropic diffusion PDEs, higher order non-linear PDEs, variational PDEs and other constrained/regularized and unconstrained models, applied to image interpolation/ reconstruction. Apart from this novel computational critical overview and presentation of the PDE image impainting models numerical analysis, the second major contribution of This work is to evaluate, especially the anisotropic diffusion PDEs, in novel real world image impainting applications related to MRI

Local Analysis of Human Cortex in MRI Brain Volume

This paper describes a method for subcortical identification and labeling of 3D medical MRI images. Indeed, the ability to identify similarities between the most characteristic subcortical structures such as sulci and gyri is helpful for human brain mapping studies in general and medical diagnosis in particular. However, these structures vary greatly from one individual to another because they have different geometric properties. For this purpose, we have developed an efficient tool that allows a user to start with brain imaging, to segment the border gray/white matter, to simplify the obtained cortex surface, and to describe this shape locally in order to identify homogeneous features. In this paper, a segmentation procedure using geometric curvature properties that provide an efficient discrimination for local shape is implemented on the brain cortical surface. Experimental results demonstrate the effectiveness and the validity of our approach

A graph-based mathematical morphology reader

This survey paper aims at providing a "literary" anthology of mathematical morphology on graphs. It describes in the English language many ideas stemming from a large number of different papers, hence providing a unified view of an active and diverse field of research

Accurate and fast 3D interactive segmentation system applied to MR brain quantification

This work presents an efficient interactive segmentation system for volumetric data-sets based on advanced 3D morphological analyses and an interaction paradigm that allows a good match with user intentions. This system has been designed to produce accurate results under the complete control of the user, to minimize the interaction time and to address a generality of 3D segmentation tasks. The system has been tested and compared with other softwares on normal MR brain structure quantification and on a challenging clinical setting pointed to the detection of the presence of subtle brain atrophy associated to primitive immunodeficiency (PID)

Interactive Segmentation and Visualization of DTI Data Using a Hierarchical Watershed Representation

Magnetic resonance diffusion tensor imaging (DTI) measures diffusion of water molecules and is used to characterize orientation of white matter fibers and connectivity of neurological structures. Segmentation and visualization of DT images is challenging, because of low data quality and complexity of anatomical structures. In this paper, we propose an interactive segmentation approach, based on a hierarchical representation of the input DT image through a tree structure. The tree is obtained by successively merging watershed regions, based on the morphological waterfall approach, hence the name watershed tree. Region merging is done according to a combined similarity and homogeneity criterion. We introduce filters that work on the proposed tree representation, and that enable region-based attribute filtering of DTI data. Linked views between the visualizations of the simplified DT image and the tree enable a user to visually explore both data and tree at interactive rates. The coupling of filtering, semiautomatic segmentation by labeling nodes in the tree, and various interaction mechanisms support the segmentation task. Our method is robust against noise, which we demonstrate on synthetic and real DTI data

A comprehensive review towards segmentation and detection of cancer cell and tumor for dynamic 3D reconstruction

Automated cancer cell and tumor segmentation and detection for 3D modeling are still an unsolved research problem in computer vision, image processing and pattern recognition research domains. Human body is complex three-dimensional structure where numerous types of cancer and tumor may exist regardless of shape or position. A three-dimensional (3D) reconstruction of cancer cell and tumor from body parts does not lead to loss of information like 2D shape visualization. Various research methodologies for segmentation and detection for 3D reconstruction of cancer cell and tumor were performed by previous research. However, the pursuit for better methodology for segmentation and detection for 3D reconstruction of cancer cell and tumor are still unsolved research problem due to lack of efficient feature extraction for details surface information, misclassification during training phases and low tissue contrast which causes low detection and precision rate with high computational complexity during detection and segmentation. This research addresses comprehensive and critical review of various segmentation and detection research methodologies for cancer affected cell and tumor in human body in the basis of three-dimensional reconstruction from MRI or CT images. At first, core research background is illustrated highlighting various aspects addressed by this research. After that, various previous methods with advantages and disadvantages followed by various phases used as frameworks exist in the previous research demonstrated by this research. Then, extensive experimental evaluations done by previous research are demonstrated by this research with various performance metrics. At last, this research summarized overall observation on previous research categorized into two aspects, i.e. observation on common research methodologies and recommended area for further research. Overall reviews proposed in this paper have been extensively studied in various research papers which can significantly contribute to computer vision research and can be potential for future development and direction for future research