MRI role in the periprosthetic lymphoma screening: a case report

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Mammography

In this volume, the topics are constructed from a variety of contents: the bases of mammography systems, optimization of screening mammography with reference to evidence-based research, new technologies of image acquisition and its surrounding systems, and case reports with reference to up-to-date multimodality images of breast cancer. Mammography has been lagged in the transition to digital imaging systems because of the necessity of high resolution for diagnosis. However, in the past ten years, technical improvement has resolved the difficulties and boosted new diagnostic systems. We hope that the reader will learn the essentials of mammography and will be forward-looking for the new technologies. We want to express our sincere gratitude and appreciation?to all the co-authors who have contributed their work to this volume

A proposal of quantum-inspired machine learning for medical purposes: An application case

Learning tasks are implemented via mappings of the sampled data set, including both the classical and the quantum framework. Biomedical data characterizing complex diseases such as cancer typically require an algorithmic support for clinical decisions, especially for early stage tumors that typify breast cancer patients, which are still controllable in a therapeutic and surgical way. Our case study consists of the prediction during the pre-operative stage of lymph node metastasis in breast cancer patients resulting in a negative diagnosis after clinical and radiological exams. The classifier adopted to establish a baseline is characterized by the result invariance for the order permutation of the input features, and it exploits stratifications in the training procedure. The quantum one mimics support vector machine mapping in a high-dimensional feature space, yielded by encoding into qubits, while being characterized by complexity. Feature selection is exploited to study the performances associated with a low number of features, thus implemented in a feasible time. Wide variations in sensitivity and specificity are observed in the selected optimal classifiers during cross-validations for both classification system types, with an easier detection of negative or positive cases depending on the choice between the two training schemes. Clinical practice is still far from being reached, even if the flexible structure of quantum-inspired classifier circuits guarantees further developments to rule interactions among features: this preliminary study is solely intended to provide an overview of the particular tree tensor network scheme in a simplified version adopting just product states, as well as to introduce typical machine learning procedures consisting of feature selection and classifier performance evaluation

Designing a secure ubiquitous mammography consultation system

This thesis attempts to design and develop a prototype for mammography image consultation that can work securely within a ubiquitous environment. Mammogram images differ largely from other type of images and it requires special and dedicated techniques to identify the required regions of interest. Thus in Chapter 2 we started to explore the affectivity of the various traditional techniques based on convolution operators (e.g. Sobol, Pretwitt, Canny) for mammography edge detection. The second part of chapter 2 tries to enhance the results obtained via the traditional techniques by hybriding some of them. The hybriding technique is called in our thesis as Pipelined Operators. In this direction we proposed four pipeline operators, which contribute to the edge enhancement as well as abnormalities rendering through the introduction of an additional coloring mechanism. Although the visualization pipelines represent in our view an advancement on the traditional techniques applied to mammograms, such pipelines expose healthcare users to further usage complexities. For this purpose we extended our research work in chapter 2 to find a better single technique that can work smoothly within the healthcare system. In this direction, we developed in the third part of chapter 2 a novel technique for finding edges based on analyzing the dynamic and fuzzy nature of edges in mammograms. We called our developed method as "Dynamic Fuzzy Classifier or the DFC"

Swarm intelligence: novel tools for optimization, feature extraction, and multi-agent system modeling

Abstract Animal swarms in nature are able to adapt to dynamic changes in their envi-ronment, and through cooperation they can solve problems that are crucial for their survival. Only by means of local interactions with other members of the swarm and with the environment, they can achieve a common goal more efficiently than it would be done by a single individual. This problem-solving behavior that results from the multiplicity of such interactions is referred to as Swarm Intelligence. The mathematical models of swarming behavior in nature were initially proposed to solve optimization problems. Nevertheless, this decentralized approach can be a valuable tool for a variety of applications, where emerging global patterns represent a solution to the task at hand. Methods for the solution of difficult computational problems based on Swarm Intelligence have been experimentally demonstrated and reported in the literature. However, a general framework that would facilitate their design does not exist yet. In this dissertation, a new general design methodology for Swarm Intelligence tools is proposed. By defining a discrete space in which the members of the swarm can move, and by modifying the rules of local interactions and setting the adequate objective function for solutions evaluation, the proposed methodology is tested in various domains. The dissertation presents a set of case studies, and focuses on two general approaches. One approach is to apply Swarm Intelligence as a tool for optimization and feature extraction, and the other approach is to model multi-agent systems such that they resemble swarms of animals in nature providing them with the ability to autonomously perform a task at hand. Artificial swarms are designed to be autonomous, scalable, robust, and adaptive to the changes in their environment. In this work, the methods that exploit one or more of these features are presented. First, the proposed methodology is validated in a real-world scenario seen as a combinatorial optimization problem. Then a set of novel tools for feature extraction, more precisely the adaptive edge detection and the broken-edge linking in digital images is proposed. A novel data clustering algorithm is also proposed and applied to image segmentation. Finally, a scalable algorithm based on the proposed methodology is developed for distributed task allocation in multi-agent systems, and applied to a swarm of robots. The newly proposed general methodology provides a guideline for future developers of the Swarm Intelligence tools. Los enjambres de animales en la naturaleza son capaces de adaptarse a cambios dinamicos en su entorno y, por medio de la cooperación, pueden resolver problemas ´ cruciales para su supervivencia. Unicamente por medio de interacciones locales con otros miembros del enjambre y con el entorno, pueden lograr un objetivo común de forma más eficiente que lo haría un solo individuo. Este comportamiento problema-resolutivo que es resultado de la multiplicidad de interacciones se denomina Inteligencia de Enjambre. Los modelos matemáticos de comportamiento de enjambres en entornos naturales fueron propuestos inicialmente para resolver problemas de optimización. Sin embargo, esta aproximación descentralizada puede ser una herramienta valiosa en una variedad de aplicaciones donde patrones globales emergentes representan una solución de las tareas actuales. Aunque en la literatura se muestra la utilidad de los métodos de Inteligencia de Enjambre, no existe un entorno de trabajo que facilite su diseño. En esta memoria de tesis proponemos una nueva metodologia general de diseño para herramientas de Inteligencia de Enjambre. Desarrollamos herramientas noveles que representan ejem-plos ilustrativos de su implementación. Probamos la metodología propuesta en varios dominios definiendo un espacio discreto en el que los miembros del enjambre pueden moverse, modificando las reglas de las interacciones locales y fijando la función objetivo adecuada para evaluar las soluciones. La memoria de tesis presenta un conjunto de casos de estudio y se centra en dos aproximaciones generales. Una aproximación es aplicar Inteligencia de Enjambre como herramienta de optimización y extracción de características mientras que la otra es modelar sistemas multi-agente de tal manera que se asemejen a enjambres de animales en la naturaleza a los que se les confiere la habilidad de ejecutar autónomamente la tarea. Los enjambres artificiales están diseñados para ser autónomos, escalables, robustos y adaptables a los cambios en su entorno. En este trabajo, presentamos métodos que explotan una o más de estas características. Primero, validamos la metodología propuesta en un escenario del mundo real visto como un problema de optimización combinatoria. Después, proponemos un conjunto de herramientas noveles para ex-tracción de características, en concreto la detección adaptativa de bordes y el enlazado de bordes rotos en imágenes digitales, y el agrupamiento de datos para segmentación de imágenes. Finalmente, proponemos un algoritmo escalable para la asignación distribuida de tareas en sistemas multi-agente aplicada a enjambres de robots. La metodología general recién propuesta ofrece una guía para futuros desarrolladores deherramientas de Inteligencia de Enjambre

Mammography Techniques and Review

Mammography remains at the backbone of medical tools to examine the human breast. The early detection of breast cancer typically uses adjunct tests to mammogram such as ultrasound, positron emission mammography, electrical impedance, Computer-aided detection systems and others. In the present digital era it is even more important to use the best new techniques and systems available to improve the correct diagnosis and to prevent mortality from breast cancer. The first part of this book deals with the electrical impedance mammographic scheme, ultrasound axillary imaging, position emission mammography and digital mammogram enhancement. A detailed consideration of CBR CAD System and the availability of mammographs in Brazil forms the second part of this book. With the up-to-date papers from world experts, this book will be invaluable to anyone who studies the field of mammography