The Cowl - v.30 - Oct 26, 1977

The Cowl - student newspaper of Providence College. Volume 30 - October 26, 1977. 12 pages. Note: The volume number printed on the banner page of this issue (XXX) duplicates the volume number for the 1967-68 academic year. There is no issue number for this issue

Adjuvant chemotherapy and survival among patients 70 years of age and younger with node-negative breast cancer and the 21-gene recurrence score of 26-30

BACKGROUND: The benefits of chemotherapy in node-negative, hormone receptor-positive, and human epidermal growth factor receptor 2 (HER2)-negative breast cancer patients with the 21-gene recurrence score (RS) of 18-30, particularly those with RS 26-30, are not known. METHODS: Using the Surveillance, Epidemiology, and End Results (SEER) data, we retrospectively identified 29,137 breast cancer patients with the 21-gene RS of 18-30 diagnosed between 2004 and 2015. Mortality risks according to the RS and chemotherapy use were compared by the Kaplan-Meier method and Cox\u27s proportional hazards model. RESULTS: Among the breast cancer patients with the RS 18-30, 21% of them had RS 26-30. Compared to breast cancer patients with RS 18-25, patients with RS 26-30 had more aggressive tumor characteristics and chemotherapy use and increased risk of breast cancer-specific mortality and overall mortality. In breast cancer patients who were aged ≤ 70 years and had RS of 26-30, chemotherapy administration was associated with a 32% lower risk of breast cancer-specific mortality (hazard ratio [HR], 0.68; 95% confidence interval [CI], 0.47-0.99) and a 42% lower risk of overall mortality (HR, 0.58; 95% CI, 0.44-0.76). Survival benefits were most pronounced in breast cancer patients who were younger or had grade III tumor. CONCLUSIONS: The 21-gene RS of 18-30 showed heterogeneous outcomes, and the RS 26-30 was a significant prognostic factor for an increased risk of mortality. Adjuvant chemotherapy could improve the survival of node-negative, hormone receptor-positive, and HER2-negative breast cancer patients with the 21-gene RS 26-30 and should be considered for patients, especially younger patients or patients with high-grade tumors

Proton dominance in the 2^+_2 -> 0^+_1 transition of N = Z\pm 2 nuclei around Si-28

E2 transitions in Si-30 are investigated in relation with intrinsic deformations based on a method of antisymmetrized molecular dynamics. By comparing E2 transition strengths in the mirror nuclei Si-30 and S-30, transition matrix amplitudes M_p and M_n for protons and neutrons are discussed in mirror analysis. Particular attention is paid to the M_n/M_p ratio in the transition from the 2^+_2 state to the 0^+_1 state. The M_n/M_p ratio in Mg-26 and Si-26 is also investigated. It is found that the proton dominance in the transition 2^+_2 -> 0^+_1 in Si-30 and Si-26 originates in the oblate trend of the Z=14 proton structure.Comment: 7 pages, 7 figure

The Cowl - v.26 - n.6 - Oct 30, 1963

The Cowl - student newspaper of Providence College. Volume 26, Number 6 - October 30, 1963. 8 pages

The Cowl - v.30 - n.2 - Jan 26, 1977

The Cowl - student newspaper of Providence College. Volume 30, Number 2 - January 26, 1977. 8 pages. Note: The volume number printed on the banner page of this issue (XXX) duplicates the volume number for the 1967-68 academic year

Optimal Auditing with Scoring Theory and Application to Insurance Fraud

Cet article établit une liaison entre la théorie de l'audit optimal et la méthodologie du scoring dans un contexte d'asymétrie d'information. L'application retenue concerne la fraude à l'assurance, mais la même approche peut être appliquée à d'autres activités qui utilisent le scoring. Nous montrons que la stratégie et l'audit optimal consistent à transmettre les demandes d'indemnité à une cellule antifraude lorsque certains indicateurs de fraude sont observés. Les indicateurs de fraude sont classés en fonction d'une probabilité de fraude croissante. Une telle stratégie demeure optimale lorsque la politique d'enquête est budgétairement contrainte. De plus, la politique d'audit agit comme un mécanisme de dissuasion et nous expliquons pourquoi elle nécessite un engagement de l'assureur et comment elle devrait affecter les incitations financières du personnel de la cellule antifraude. Le modèle est calibré avec les données d'un grand assureur européen. Nous calculons une valeur critique d'un indice de suspicion de fraude qui fournit un seuil au delà duquel toutes les demandes d'indemnité doivent être soumises à audit et nous évaluons le gain potentiel qui pourrait être dérivé de la politique d'audit optimal. Nous montrons qu'il est possible d'améliorer ces résultats en séparant différents groupes d'assurés avec des coûts psychologiques de fraude différents. Enfin nos résultats montrent comment l'effet de dissuasion peut être pris en compte et comment il affecte la stratégie optimale d'audit.

Coconut Phytophthora. Workshop proceedings, 26-30 October 1992, Manado, Indonesia

Ce séminaire sur le Phythophthora du cocotier avait pour but de réunir tous les acteurs d'un projet démarré en 1990 et de faire le point sur les études réalisées pour la connaissance et la lutte contre ce champignon. Ce projet a donné une grande priorité aux échanges d'informations et aux complémentarités entre les équipes de recherche européennes et tropicale

The New Hampshire, Vol. 106, No. 26 (Jan. 30, 2017)

An independent student produced newspaper from the University of New Hampshire