Analysis of mitochondrial distribution in different cross-sections.
<p>(A) Cross-section 1 with mitochondria segmented in green and sarcolemma in red. (B) Square windows representing the ratio of mitochondrial area vs myofibrilar area present inside these windows (C) Statistical box plots of the distribution of these ratios corresponding to different sizes of the square windows. The star in the middle of box plots represents the area fraction of total mitochondria present in section 1. (D-F): Box plot representing the distribution of mitochondrial density at various points in the cross-section 1–3. The stars represent the total mitochondrial area fraction present in each cross section. Mitochondrial area fraction is 55% in section 2 and 3 and 45% in section 1.</p
Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Biotechnology, Cancer, Plant Biology, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, mitochondrial CK enzymes, impact, electron microscope images, metabolite distributions, creatine phosphate, bioenergetic, mitochondria aggregated, mitochondrial distributions, force production, mitochondrial arrangement, twitch duration, reactions act, cell cross-section, cell architecture, force dynamics, mitochondrial organization, uniform force dynamics, diffusion, hypoxia activity, uniform ATP, creatine kinase, element modeling, electron microscopy data, PCr shuttle, mitochondrial organisation, force generation, ADP ratios, phosphate compounds
DOI identifier: 10.1371/journal.pcbi.1006640.g002
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