Clinical use of plasma chitotriosidase in severe sepsis

Abstract

<div><p></p><p>Plasma chitotriosidase activity (ChT) was previously proposed to quantify severity of sepsis. In a complex surgical case, with prolonged sepsis and consistently high ChT, we found that the least increased values occurred in stages of extreme illness, with profound hypocholesterolemia. ChT needs a better characterization before becoming a reliable biomarker of septic evolution.</p></div