Alatoom

Androulla Efstratiou

Ann Sandison

Asuka Leslie

Azhar

Barzantny

Berger

Bernard

Bizzini

Blue

Bolt

Bonmarin

Bonnet

Burkovski

Corti

Coyle

De Zoysa

Dewinter

Dias

Edmunds

Edwards

Efstratiou

Elden

Elek

Engler

Funke

Hogg

Holmes

Katsukawa

Kerrin

Klebs

Kneen

Konrad

König

Lartigue

Leitz

Lindhusen-Lindhé

Logina

Lowe

Luke S P Moore

Margie Meltzer

Markina

McCloskey

McElvania Tekippe

Mina

Mokrousov

Naglich

Owens

Pallen

Pappenheimer

Reacher

Reithinger

Rogers

Schuhegger

Schulthess

Serwold-Davis

Sevigny

Shiranee Sriskandan

Sing

Taylor

Tiwari

Trost

Varghese

Wagner

Wilson

Zamiri

Zeegelaar

Crossref

The Lancet Infectious Diseases

Corynebacterium ulcerans cutaneous diphtheria

We describe the case of a patient with cutaneous diphtheria caused by toxigenic Corynebacterium ulcerans who developed a right hand flexor sheath infection and symptoms of sepsis such as fever, tachycardia, and elevated C-reactive protein, after contact with domestic cats and dogs, and a fox. We summarise the epidemiology, clinical presentation, microbiology, diagnosis, therapy, and public health aspects of this disease, with emphasis on improving recognition. In many European countries, C ulcerans has become the organism commonly associated with cutaneous diphtheria, usually seen as an imported tropical disease or resulting from contact with domestic and agricultural animals. Diagnosis relies on bacterial culture and confirmation of toxin production, with management requiring appropriate antimicrobial therapy and prompt administration of antitoxin, if necessary. Early diagnosis is essential for implementation of control measures and clear guidelines are needed to assist clinicians in managing clinical diphtheria. This case was a catalyst to the redrafting of the 2014 national UK interim guidelines for the public health management of diphtheria, released as final guidelines in March, 2015

Moore, LS

Leslie, A

Meltzer, M

Sandison, A

Efstratiou, A

Sriskandan, S

Spiral - Imperial College Digital Repository

Corynebacterium ulcerans cutaneous diphtheria.

http://spiral.imperial.ac.uk/bitstream/10044/1/25843/2/Corynebacterium%20ulcerans%20cutaneous%20diphtheria_Final.pdf

Corynebacterium ulcerans cutaneous diphtheria.

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Crossref

Spiral - Imperial College Digital Repository