Role of transdermal potential difference during intophoretic drug delivery.

Potential differences have been measured during transdermal iontophoresis in order to establish the effect of voltage, as opposed to current, on cutaneous blood flow. It is known that, even in the absence of drugs, the iontophoresis current can sometimes produce increased blood flow. The role of voltage in this process is studied through single-ended measurements (between electrode and body) of the potential difference during iontophoresis with 100-/spl mu/A, 20-s current pulses through deionized water, saturated 20.4% NaCl solution, 1 % acetylcholine, and 1 % sodium nitroprusside. It is found that the voltage needed to deliver the current varied by orders of magnitudes less than the differences in the conductance of these different electrolytes, and it is concluded that, at least for the present current protocol, the voltage as such is not an important factor in increasing the blood flow

Ionization Contact Potential Difference Gyroscope

An ionization contact potential difference gyroscope including a housing enclosing a first and second electrode with a gas, further including an ionization source capable of providing ions from the gas, and a contact potential difference measurement circuit that is capable of measuring an electrical signal related to the amount of ions striking at least one of the two surfaces. The measurement circuit of the present invention is capable of sensing the small amount of electrical current flowing as the electrons and ions strike one or both of the surfaces.Georgia Tech Research Corporatio

Thermal power transfer system using applied potential difference to sustain operating pressure difference

A thermal power transfer system using a phase change liquid gas fluid in a closed loop configuration has a heat exchanger member connected to a gas conduit for inputting thermal energy into the fluid. The pressure in the gas conduit is higher than a liquid conduit that is connected to a heat exchanger member for outputting thermal energy. A solid electrolyte member acts as a barrier between the gas conduit and the liquid conduit adjacent to a solid electrolyte member. The solid electrolyte member has the capacity of transmitting ions of a fluid through the electrolyte member. The ions can be recombined with electrons with the assistance of a porous electrode. An electrical field is applied across the solid electrolyte member to force the ions of the fluid from a lower pressure liquid conduit to the higher pressure gas conduit

Potential difference methods for measuring crack growth: A review

© 2020 Elsevier Ltd Non-destructive testing techniques are widely applied in industry for the evaluation of quantities of interest without inflicting additional damage accumulation. Crack detection and monitoring is a prime example of where non-destructive testing is valuable. Among the variety of non-destructive testing techniques, the direct current and alternating current potential difference methods, which are based on the principle that an electrical potential field around a conductive specimen is disturbed by the presence of geometric irregularities (or “features”), have received a great deal of attention in the literature. This is mainly due to the high levels of accuracy associated with these techniques and good estimations of crack initiation and propagation having been achieved. A critical review of the evolution and applications of potential difference methods is presented in this paper. Potential difference methods are capable of providing accurate and continuous measurements with simple installation and exclude the requirement of visual access under harsh service conditions. Alternating current potential difference methods require lower current input than direct current equivalents and hence provide higher sensitivity and offer better noise rejection but are vulnerable to capacitance effects and are more expensive. Calibration curves can be determined analytically, numerically, or by direct or analogue experimental techniques with each method offering strengths and limitations. Application of these should be determined in accordance with the specific scenario. The performance of electric probes (of voltage measurements and current injection) on top- and side-face of C(T) and SEN(B) specimens are reviewed in detail as case examples. Specific guidance in normalising measurements and eliminating errors from thermoelectric effects can be implemented in order to improve the accuracy of PD methods. Abundant results have been obtained by applying PD methods in monitoring cracks geometries under aggressive conditions such as corrosion, high temperature, creep and cycled loading

Inhomogeneously doped two-leg ladder systems

A chemical potential difference between the legs of a two-leg ladder is found to be harmful for Cooper pairing. The instability of superconductivity in such systems is analyzed by compairing results of various analytical and numerical methods. Within a strong coupling approach for the t-J model, supplemented by exact numerical diagonalization, hole binding is found unstable beyond a finite, critical chemical potential difference. The spinon-holon mean field theory for the t-J model shows a clear reduction of the the BCS gaps upon increasing the chemical potential difference leading to a breakdown of superconductivity. Based on a renormalization group approach and Abelian bosonization, the doping dependent phase diagram for the weakly interacting Hubbard model with different chemical potentials was determined.Comment: Revtex4, 11 pages, 7 figure