Report on the new boat "Alexander Agassiz" of the La Jolla Marine Station

The San Diego Marine Biological Association was briefly known as the La Jolla Marine Station, and then became the Scripps Institution of Oceanography in 1912. This report mentions the building of the first ship, the Alexander Agassiz, for the institution

Caltech and aeronautics: a presentation by the California Institute of Technology

The outstanding accomplishment of Caltech in the field of aeronautics is not that it has taught, but that it has always had something new to teach. When most aircraft were glued together from bamboo, balsawood, and canvas, Caltech was teaching the next generation of designers how to build hollow shells of stiffened sheet metal. Today, at the threshold of the Space Age, Caltech is combining astronomy, mathematics, physics, mechanics and chemistry into a new sort of aeronautical science, tailored to the needs of a new era that knows no spatial limitations. To an important extent, Caltech's contributions to industrial and military aeronautics have been made possible, through the years, by equally valuable contributions, in the form of men, money, and equipment, from industry and government. This support has filled a vital need in the past; it will become even more important in the future. The following pages tell something of Caltech's role in aeronautics, its research accomplishments, its success as a teacher of men. Most important, this booklet sets forth the direction of Caltech's present and future research. It is an exciting vista

Moral tragedy

Polemizując z poglądami niektórych filozofów moralności, autor broni tezy, iż jednoznacznie dobrzy ludzie mogą być pewni spokoju swej duszy

Walmart Sweatshop Litigation Dismissed

Document from the 9th Circuit Court in California dismissing charges brought up by employees of Wal-Mart\u27s foreign suppliers. The case was dismissed on the grounds that the plaintiffs did not state a claim against Wal-Mart, only its suppliers, which Wal-Mart had no legal duty to monitor

Human Pleural Fluid Elicits Pyruvate and Phenylalanine Metabolism in Acinetobacter baumannii to Enhance Cytotoxicity and Immune Evasion

The CCAAT box-harboring proteins represent a family of heterotrimeric transcription factors which is highly conserved in eukaryotes. In fungi, one of the particularly important homologs of this family is the Hap complex that separates the DNA-binding domain from the activation domain and imposes essential impacts on regulation of a wide range of cellular functions. So far, a comprehensive summary of this complex has been described in filamentous fungi but not in the yeast. In this review, we summarize a number of studies related to the structure and assembly mode of the Hap complex in a list of representative yeasts. Furthermore, we emphasize recent advances in understanding the regulatory functions of this complex, with a special focus on its role in regulating respiration, production of reactive oxygen species (ROS) and iron homeostasis.Fil: Nyah, Rodman. California State University; Estados UnidosFil: Martinez, Jasmine. California State University; Estados UnidosFil: Fung, Sammie. California State University; Estados UnidosFil: Nakanouchi, Jun. California State University; Estados UnidosFil: Myers, Amber L.. California State University; Estados UnidosFil: Harris, Caitlin M.. California State University; Estados UnidosFil: Dang, Emily. California State University; Estados UnidosFil: Fernandez, Jennifer. California State University; Estados UnidosFil: Liu, Christine. California State University; Estados UnidosFil: Mendoza, Anthony M.. California State University; Estados UnidosFil: Jimenez, Verónica. California State University; Estados UnidosFil: Nikolaidis, Nikolas. California State University; Estados UnidosFil: Brennan, Catherine A.. California State University; Estados UnidosFil: Bonomo, Robert A.. Louis Stokes Cleveland Department of Veterans Affairs Medical Cente; Estados Unidos. Center for Antimicrobial Resistance and Epidemiology; Estados Unidos. Case Western Reserve University School of Medicine; Estados UnidosFil: Sieira, Rodrigo. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquímicas de Buenos Aires. Fundación Instituto Leloir. Instituto de Investigaciones Bioquímicas de Buenos Aires; ArgentinaFil: Ramirez, Maria Soledad. California State University; Estados Unido

Human Developmental Chondrogenesis as a Basis for Engineering Chondrocytes from Pluripotent Stem Cells

Joint injury and osteoarthritis affect millions of people worldwide, but attempts to generate articular cartilage using adult stem/progenitor cells have been unsuccessful. We hypothesized that recapitulation of the human developmental chondrogenic program using pluripotent stem cells (PSCs) may represent a superior approach for cartilage restoration. Using laser-capture microdissection followed by microarray analysis, we first defined a surface phenotype (CD166(low/neg)CD146(low/neg)CD73(+)CD44(low)BMPR1B(+)) distinguishing the earliest cartilage committed cells (prechondrocytes) at 5-6 weeks of development. Functional studies confirmed these cells are chondrocyte progenitors. From 12 weeks, only the superficial layers of articular cartilage were enriched in cells with this progenitor phenotype. Isolation of cells with a similar immunophenotype from differentiating human PSCs revealed a population of CD166(low/neg)BMPR1B(+) putative cartilage-committed progenitors. Taken as a whole, these data define a developmental approach for the generation of highly purified functional human chondrocytes from PSCs that could enable substantial progress in cartilage tissue engineering.Fil: Wu, Ling. University of California at Los Angeles; Estados UnidosFil: Bluguermann, Carolina. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia. Laboratorio de Biología del Desarrollo Celular; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. University of California at Los Angeles; Estados UnidosFil: Kyupelyan, Levon. University of California at Los Angeles; Estados UnidosFil: Latour, Brooke. University of California at Los Angeles; Estados UnidosFil: Gonzalez, Stephanie. University of California at Los Angeles; Estados UnidosFil: Shah, Saumya. University of California at Los Angeles; Estados UnidosFil: Galic, Zoran. University of California at Los Angeles; Estados UnidosFil: Ge, Sundi. University of California at Los Angeles; Estados UnidosFil: Zhu, Yuhua. University of California at Los Angeles; Estados UnidosFil: Petrigliano, Frank A.. University of California at Los Angeles; Estados UnidosFil: Nsair, Ali. University of California at Los Angeles; Estados UnidosFil: Miriuka, Santiago Gabriel. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia. Laboratorio de Biología del Desarrollo Celular; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Li, Xinmin. University of California at Los Angeles; Estados UnidosFil: Lyons, Karen M.. University of California at Los Angeles; Estados UnidosFil: Crooks, Gay M.. University of California at Los Angeles; Estados UnidosFil: McAllister, David R.. University of California at Los Angeles; Estados UnidosFil: Van Handel, Ben. Novogenix Laboratories; Estados UnidosFil: Adams, John S.. University of California at Los Angeles; Estados UnidosFil: Evseenko, Denis. University of California at Los Angeles; Estados Unido

Species Profiles: Life Histories and Environmental Requirements of Coastal Fishes and Invertebrates (Pacific Southwest): Northern anchovy

Three genetically distinct groups: British Columbia to northern California, Southern California to the northern Baja peninsula, and central and southern Baja California. (PDF contains 21 pages

Highlights of the Foundation Center's 2001 Study: California Foundations - A Profile of the State's Grantmaking Community

California Foundations: A Profile of the State's Grantmaking Community provides the most comprehensive analysis to date of private and community foundations in California. The report is divided into two major components. The first section documents the size, scope, and giving patterns of the California foundation community and compares them with national trends. It also includes an examination of giving by national funders in California. The second section presents separate "statistical profiles" illustrating the dimensions and growth of foundation communities in five selected California metropolitan areas—Los Angeles, Oakland, San Diego, San Francisco, and San Jose. This report was developed in collaboration with the Center on Philanthropy and Public Policy at the University of Southern California

The anchovy reduction fishery for the 1977-78 season

Landings for the 1977-78 season were 62,118 metric tons (68,476 tons) in southern California and 6,541 metric tons (7,212 tons) in central California. The southern area's samples were characterized by the dominance of the 1976 year class (38%) while central California data indicated the 1977 year class (38%) as the most abundant year class. Sex ratios indicated a near 1:1 ratio for both southern and central California. (24pp.

Defunding Higher Education: What Are the Effects on College Enrollment?

Examines the effects of the state's higher education spending cuts on enrollment rates of eligible, highly prepared students at the University of California, California State University, and California Community Colleges systems. Outlines implications