827 research outputs found

    Detecting a set of entanglement measures in an unknown tripartite quantum state by local operations and classical communication

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    We propose a more general method for detecting a set of entanglement measures, i.e. negativities, in an \emph{arbitrary} tripartite quantum state by local operations and classical communication. To accomplish the detection task using this method, three observers, Alice, Bob and Charlie, do not need to perform the partial transposition maps by the structural physical approximation; instead, they are only required to collectively measure some functions via three local networks supplemented by a classical communication. With these functions, they are able to determine the set of negativities related to the tripartite quantum state.Comment: 16 pages, 2 figures, revte

    On the local convergence of an iterative approach for inverse singular value problems

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    AbstractThe purpose of this paper is to provide the convergence theory for the iterative approach given by M.T. Chu [Numerical methods for inverse singular value problems, SIAM J. Numer. Anal. 29 (1992), pp. 885–903] in the context of solving inverse singular value problems. We provide a detailed convergence analysis and show that the ultimate rate of convergence is quadratic in the root sense. Numerical results which confirm our theory are presented. It is still an open issue to prove that the method is Q-quadratic convergent as claimed by M.T. Chu

    Noiseless method for checking the Peres separability criterion by local operations and classical communication

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    We present a method for checking Peres separability criterion in an arbitrary bipartite quantum state ρAB\rho_{AB} within local operations and classical communication scenario. The method does not require the prior state reconstruction and the structural physical approximation. The main task for the two observers, Alice and Bob, is to estimate some specific functions. After getting these functions, they can determine the minimal eigenvalue of ρABTB\rho^{T_{B}}_{AB}, which serves as an entanglement indicator in lower dimensions.Comment: 10 pages, 2 figure

    Dynamic Analysis of Traffic State and Congestion Propagation on Bidirectional Grid Network

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    Many traffic problems in China such as traffic jams and air pollutions are mainly caused by the increasing traffic volume. In order to alleviate the traffic congestion and improve the network performance, the analysis of traffic state and congestion propagation has attracted a great interest. In this paper, an improved mesoscopic traffic flow model is proposed to capture the speed-density relationship on segments, the length of queue, the flow on links, and so forth, The self-developed dynamic traffic simulation software (DynaCHINA) is used to reproduce the traffic congestion and propagation in a bidirectional grid network for different demand levels. The simulation results show that the proposed model and method are capable of capturing the real traffic states. Hence, our results can provide decision supports for the urban traffic management and planning

    A seven-gene signature predicts overall survival of patients with colorectal cancer

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    Colorectal cancer (CRC) is a major cause of global cancer mortality. Gene expression profiles can help predict prognosis of patients with CRC. In most of previous studies, disease recurrence was analyzed as the survival endpoint. Thus we aim to build a robust gene signature for prediction of overall survival (OS) in patients with CRC. Fresh frozen CRC tissues from 64 patients were analyzed using Affymetrix HG-U133plus 2.0 gene arrays. By performing univariate survival analysis, 6487 genes were found to be associated with the OS in our cohort. KEGG analysis revealed that these genes were mainly involved in pathways such as endocytosis, axon guidance, spliceosome, Wnt signalling and ubiquitin mediated proteolysis. A seven-gene signature was further selected by a robust likelihood-based survival modelling approach. The prognostic model of seven-gene signature (NHLRC3, ZDHHC21, PRR14L, CCBL1, PTPRB, PNPO, and PPIP5K2) was constructed and weighted by regression coefficient, which divided patients into high- and low-risk groups. The OS for patients in high-risk group was significantly poorer compared with patients in low-risk group. Moreover, all seven genes were found to be differentially expressed in CRC tissues as compared with adjacent normal tissues, indicating their potential role in CRC initiation and progression. This seven-gene signature was further validated as an independent prognostic marker for OS prediction in patients with CRC in other two independent cohorts. In short, we developed a robust seven-gene signature that can predict the OS for CRC patients, providing new insights into identification of CRC patients with high risk of mortality

    Tick-borne encephalitis virus induces chemokine RANTES expression via activation of IRF-3 pathway.

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    BACKGROUND: Tick-borne encephalitis virus (TBEV) is one of the most important flaviviruses that targets the central nervous system (CNS) and causes encephalitides in humans. Although neuroinflammatory mechanisms may contribute to brain tissue destruction, the induction pathways and potential roles of specific chemokines in TBEV-mediated neurological disease are poorly understood. METHODS: BALB/c mice were intracerebrally injected with TBEV, followed by evaluation of chemokine and cytokine profiles using protein array analysis. The virus-infected mice were treated with the CC chemokine antagonist Met-RANTES or anti-RANTES mAb to determine the role of RANTES in affecting TBEV-induced neurological disease. The underlying signaling mechanisms were delineated using RANTES promoter luciferase reporter assay, siRNA-mediated knockdown, and pharmacological inhibitors in human brain-derived cell culture models. RESULTS: In a mouse model, pathological features including marked inflammatory cell infiltrates were observed in brain sections, which correlated with a robust up-regulation of RANTES within the brain but not in peripheral tissues and sera. Antagonizing RANTES within CNS extended the survival of mice and reduced accumulation of infiltrating cells in the brain after TBEV infection. Through in vitro studies, we show that virus infection up-regulated RANTES production at both mRNA and protein levels in human brain-derived cell lines and primary progenitor-derived astrocytes. Furthermore, IRF-3 pathway appeared to be essential for TBEV-induced RANTES production. Site mutation of an IRF-3-binding motif abrogated the RANTES promoter activity in virus-infected brain cells. Moreover, IRF-3 was activated upon TBEV infection as evidenced by phosphorylation of TBK1 and IRF-3, while blockade of IRF-3 activation drastically reduced virus-induced RANTES expression. CONCLUSIONS: Our findings together provide insights into the molecular mechanism underlying RANTES production induced by TBEV, highlighting its potential importance in the process of neuroinflammatory responses to TBEV infection

    On the Local Convergence of an Iterative Approach for Inverse Singular Value Problems

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    The purpose of this paper is to provide the convergence theory for the iterative approach given by Chu [SIAM J. Numer. Anal.,29 (1992), pp. 885–903] in the context of solving inverse singular value problems. We give a detailed convergence analysis and investigate the ultimate rate of convergence. Numerical results which confirm our theory are presented

    (E)-4-(β-d-Allopyran­os­yloxy)cinnamyl 4-bromo­phenyl ketone ethanol solvate

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    The title compound, C21H21BrO7·C2H6O, was synthesized by the Claisen–Schimidt reaction of helicid (systematic name: 4-formyl­phenyl-β-d-allopyran­oside) with 4-bromo­aceto­phenone in ethanol. The pyran ring adopts a chair conformation. In the crystal structure, mol­ecules are linked into a three-dimensional network by inter­molecular O—H⋯O hydrogen bonds

    2-[3-((Z)-2-{4-[Bis(2-chloro­eth­yl)amino]­phen­yl}ethen­yl)-5,5-dimethyl­cyclo­hex-2-en-1-yl­idene]propane­dinitrile

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    The highly conjugated title compound, C23H25Cl2N3, is nearly planar (the mean deviation from the plane being 0.049 Å), except for the –C(CH3)2 group on the cyclo­hexene ring and the two CH2Cl groups. The cyclo­hexene ring has an envelope configuration. In the crystal, the packing is stabilized by C—H⋯Cl inter­actions and C—H⋯π inter­actions involving the benzene ring

    Can Overconfidence be Debiased by Low-Probability/High-Consequence Events?

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    During the first half of 2008, China suffered three natural disasters: a heavy snow storm, an outbreak of hand-foot-mouth disease, and a severe earthquake. The aim of the present study is to explore how low-probability/high-consequence events influence overconfidence. In Study 1, opportunity samples were obtained by recruiting residents in three different types of disaster-hit areas to answer a peer-comparison probability judgment questionnaire about 1 month after the corresponding disaster occurred. The performance of 539 participants in disaster-hit areas was compared with that of 142 residents in a nondisaster area. The findings indicate that residents in disaster-hit areas were less overconfident than those in the nondisaster area on both positive and negative events. In Study 2, we surveyed a total of 336 quake-victims 4 and 11 months after the earthquake to examine whether the impact of disasters on overconfidence would decay with time. The resulting data indicate that the disaster victims became more overconfident as time elapsed. The overall findings suggest that low-probability/high-consequence events could make people less overconfident and more rational and seem to serve as a function of debiasing.</p
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