オンラインシステムを用いた学生生活支援サービス

In this research, we built and administered a syllabus registration system, a course registration system, and a portal system for Shikoku University. These are server-side applications using HTTP server. For this reason users can use them regardless of their OS, browser, or hardware. Browing information about the campus is easier now than it\u27s ever been.We think that these systems will be of great benefit to students. In this paper, we give an outline of the system and explain how it works

学官連携による「阿波ナビ」魅力向上プロジェクト

The Project for Boosting the Appeal of Awa Navi was commenced as part of an academiagovernment project by Tokushima Prefecture, private enterprises and Shikoku University. This project involved the renewal of Awa Navi, a website managed by the Tourism Planning Division of Tokushima Prefecture and the Tokushima Tourist Association, which provides tourist information. The sole objective was not "industry", but it provided technical support to the academia-led academiagovernment collaboration, which was worked on with students through coursework. It was valuable as the "best practice" on how to proceed with new academiagovernment collaborations. The work-flow used for producing websites was applied to execute the project and it was used by people from the different disciplines of academia and government as the compass to advance the project smoothly towards the single goal of producing a website. The work-flow of website production was also reflected in the coursework and the students got involved in direction and design. In the year leading up to the launch of Awa Navi, they practiced everything from website production to development, including planning and design, much like an OJT(Onthe-Job Training)

Distinguishing two distinct types of salivary extracellular vesicles: a potential tool for understanding their pathophysiological roles

Extracellular vesicles (EVs), which are found in almost all cells and human body fluids, are currently being studied as a source of pathophysiological information. Previously, we demonstrated that at least two types of EVs can be isolated from human whole saliva (WS) using enzymatic activity of dipeptidyl peptidase IV (DPP IV) as a marker for differentiating the EV subsets. In the present study, EV fractions, termed EV-I 20 k-ppt and EV-II 100 k-ppt, were prepared by a combination of size-exclusion chromatography of improved condition and sequential centrifugation. The EV-I 20 k-ppt fraction contained medium/large EVs with a diameter of 100–1,000 nm, including aminopeptidase N (APN), mucin 1, ezrin, and Annexin A1. EV-II 100 k-ppt contained small EVs with a diameter of 20–70 nm, with DPP IV and CD9, programmed cell death 6-interacting protein, and tumor susceptibility gene 101 as characteristic proteins. Proteomic analyses also revealed distinctive repertoires of constituent proteins. Immunoprecipitation of several membrane proteins of the EVs with respective antibodies suggested their differential local membrane environment between the two types of salivary vesicles. Thus, we identified two distinctive types of EVs, one is APN/MUC1- rich EVs (EV-I, large/medium EVs) and the other is DPP IV/CD9-rich EVs (EV-II, small EVs). Furthermore, analysis of the binding of the EVs to coronavirus spike proteins showed that EV-II 100 k-ppt, but not EV-I 20 k-ppt, significantly bound to the spike protein of Middle East respiratory syndrome coronavirus (MERS-CoV). Finally, we developed a simple method to prepare two distinctive EVs from only 1 mL of human WS using sequential immunoprecipitation. Elucidating the features and functions of these two types of salivary EVs may help us understand their pathophysiological roles in the oral cavity and gastrointestinal tract

Activated Carbon Impregnated with Elementary Iodine: Applications against Virus- and Bacteria-Related Issues

An iodine-doped activated carbon (named IodAC) was developed by adsorbing molecular iodine (I2) on commercially available activated carbon (AC). Iodine was selected with the purpose to add its well-known antibacterial and antiviral properties to the AC and in order to produce an innovative material for environmental pathogens control and for healthcare-related applications. The impregnation method achieved the goal of strongly adsorbing iodine on the AC surface, since both volatility and water solubility resulted to be negligible, and therefore it did not affect the stability of the material. An antibacterial test (on Escherichia coli) and an antiviral test (on an avian influenza strain) were conducted, showing the effectiveness of IodAC against the pathogens. In addition, IodAC was also compared to slaked lime (a material widely used for disinfection of outdoor spaces and livestock farming areas). The data proved the performance of IodAC against virus and bacteria and also evidenced a more stable and long-lasting disinfecting power of IodAC compared to slaked lime, the later reacting with carbon dioxide and suffering a gradually decrease of its disinfectant power; such drawback does not affect IodAC. Overall, the presented results show that IodAC can be used for a wide range of applications, including as a granular disinfectant for public spaces, for water disinfection, zoonotic diseases countermeasures (e.g., as an animal feed additive for avian influenza control), post-harvest food storage, and sanitization. Its characteristics also indicate its potential to be used for medical treatments, such as for blood, intestinal (for HIV, sepsis, irritable syndrome, ulcerative colitis therapy), and medical supplies (antibacterial bandages, gauze, cotton, etc.) sterilization