種々のカチオン染料で染色したアクリル繊維のハロクロミズム

Halochromic color changes have been studied in acrylic fibers dyed with various types of cationic dyes. Hypsochromic color changes were observed in the PAN-rH (having the sulphonic acid group in the acid form) fibers dyed with aminoanthraquinone dyes and triphenylmethane dyes, but no spectral changes were observed in those dyed with thiazoleazo dyes. Spectral changes in the dyed PAN-rH were similar to those in aqueous solutions at 0.1～0.01mol/l acid concentrations which are equivalent to the amount of acid groups; 0.04mol/kg fiber. This can be understood to be due to the protonation onto the dye molecule by the sulphonic acid groups in the treated fiber. The protonation was thought to occur in the chromogenic part of the dye molecule

Diagnosing nocturnal frontal lobe epilepsy: A case study of two children

AbstractWe describe two children of nocturnal frontal lobe epilepsy (NFLE) diagnosed using carefully observed nocturnal sleep EEGs and detailed patient histories.Case #1, a 14-year-old boy, showed repeated generalized tonic convulsions and frequent eyes opening seizures during sleep. Conventional EEGs – done with the patient awake or in sleep stage I – showed no abnormalities, while a nocturnal sleep EEG – done during in sleep stage II – revealed the repeated, sharp wave bursts predominantly in the right frontal lobe characteristic of NFLE. During these wave bursts, we noticed the boy's eyes opening, although his parents had not been aware this NFLE symptom.Case #2, a 12-year-old boy, showed one daytime generalized convulsion. He had also been suffering from repeated paroxysmal episodes similar to parasomnia – waking up, sitting, walking, screaming, and speaking – which always followed the same patterns lasting several minutes. During the nocturnal sleep EEG, episodes occurred twice, showing abnormal epileptic discharges predominantly in the frontal lobe. His parents did not mention the episodes to us until questioned, as they had recognized them as parasomnia. The previous conventional EEG showed abnormal slow waves in the frontal lobe, which led us to suspect frontal lobe epilepsy and to take a detailed patient history.The frequency and stereotypy of their symptoms during sleep caused us to perform nocturnal sleep EEGs and led us NFLE diagnosis. Detailed patient histories including sleep habits and carefully observed nocturnal sleep EEGs enabled us to recognize these NFLE clinical features

Prospective Study on the Incidence of Bone Metastasis (BM) and Skeletal-Related Events (SREs) in Patients (pts) with Stage IIIB and IV Lung Cancer—CSP-HOR 13

Background:Bone metastasis (BM) is a frequent complication in patients with advanced lung cancer and it causes skeletal-related events (SREs). Our study aim is to prospectively investigate the incidence of BM, incidence and types of SRE, and predictive factors of BM and SREs.Methods:Newly diagnosed, advanced non–small-cell lung cancer (NSCLC) or small-cell lung cancer (SCLC) patients were enrolled into the study. Patients were followed up every 4 weeks to monitor the development of SREs. Treatment for lung cancer was performed at the discretion of the investigator.Results:Two hundred seventy-four patients were enrolled in this study between April 2007 and December 2009 from 12 institutions. Patients included 77 cases of SCLC and 197 of NSCLC (stage IIIB/IV = 73/124). Median follow-up time was 13.8 months. The incidence of BM at initial diagnosis was 48% in stage IV NSCLC and 40% in extensive stage (ED)-SCLC. Forty-five percent of patients who developed BM had SREs consisting of pathologic fracture (4.7%), radiation to bone (15.3%), spinal cord compression (1.1%), and hypercalcemia (2.2%). Multivariate analysis revealed that factors predicting BM are stage IV, performance status 1 or greater and higher bone alkaline phosphatase in NSCLC patients, higher lactate dehydrogenase, and lower parathyroid hormone–related peptide in SCLC patients. Factors predicting SREs were stage IV, age 64 or younger, and lower albumin in NSCLC patients. Multivariate analysis of SRE was not performed for SCLC because of the small number of events.Conclusion:Predictive factors should be taken into consideration in future randomized studies evaluating BM and SREs

Effects of a Chemically Synthesized Leucine-Rich Amelogenin Peptide (csLRAP) on Chondrogenic and Osteogenic Cells

福岡歯科大学2017年

繊維集合体における微小面積部分の配色に関する研究(第4報) : 2色杢糸における色の見分けとメランジ配色の効果

Color discrimination and desirable melange effect in the colored two-ply yarns were assessed by 20 observers in visual testing the seriplanes of the plied two-colored yarns together with the dyed single yarns of three primary colors and of 12 vivid colors, respectively, which were carefully prepared after color-matching with the color cards of vivid tone on the color ring of PCCS (Practical Color Coordinate System). The results of the color discrimination and desirable color combinations were discussed in the relation to color differences between the two colors in the ply yarns. It was necessary for desirable melange color effect of the two colored ply yarns to select medium hue contrast combination. High hue contrast combination to be consequently high color differences between the two colored yarns led the color discrimination to improve, while it also led the desirable melange effect to change for the worse. The result of the desirable color effects in the colored yarns was different from that in the colored fiber assemblies previously reported, due to size as a visual object

ハーブで染色した絹布の抗菌活性について

The mordanted silk fabrics were dyed with six herbal plants applicable as medical herb having various pharmacodynamic effects. The dyed silk fabrics displayed attractive appearance in color. However, their color range was limitted in yellowish brown and their color depth was covered from light to medium shade. Their color fastness was acceptable level for apparel end-uses. Antibacterial activity of the silk fabrics dyed with herbs against Staphylococcus aureus IFO12732 and Escherichia coli K12 W3110 were measured by JIS L-1902 Test Method. Bactericidel activities were exhibited by the fabrics dyed with sage, rosemary, lavender and thyme among six herbs. It was found that pharmacodynamic effects of medicinal herbs used as plant dyes can be confirmed even in the dyed form on the silk fabrics. The antibacterial activity of these herb-dyed silk fabrics was in the acceptable level as an antibacterial substance

n-Alkyl-dimethyl-3-chloro-2-hydroxypropylammonium chloridesによりカチオン化されたセルロース繊維の直接染料による染色

n-Alkyl-dimethyl-3-chloro-2-hydroxypropylammonium chlorides having an alkyl group of different chain lengths 1, 8 and 16, were applides as cationizing agents for preparing the cationized cellulosic fibers. The cationized fibers having alkyl chain length of 1 and 8 displayed the high level of the dye-exhaustion in dyeing with direct dyes, C.I.Direct Black 22, without the addition of electrolyte. The dyed fibers were superior in color fastness to the dyed original cellulosic fiber, whereas the dyed fiber having alkyl chain length of 16 was considerably inferior. And the dyed fiber having alkyl length of C16 with C.I.Direct Black 22 showed a dark wine color, which was much different from the black color of the dyed fibers having alkyk chain length of 1 and 8, the original. The dyeing properties and mechanism of the cationized fibers having different alkyl chain length with direct dye were discussed

n-Alkyldimethyl-3-chloro-2-hydroxypropylammonium chloridesによりカチオン化されたセルロース繊維の反応染料による染色

The cationized cellulosic fibers with n-alkyldimethyl-3-chloro-2-hydroxypropylammonium chlorides having an alkyl group of different chain lengths were dyed with several reactive dyes under the recommendable dyeing recipe from the dyestuff producers. In practical dyeing recipe of cellulosic fiber with reactive dye the enormous amount of electrolyte (ex. sodium sulfate) is applied to promote the dye adosorption on the fiber prior to chemical reaction of fiber with dye. The cationized fibers resulted in a high level of dye-exhaustion in dyeing with reactive dyes without the addition of electrolyte. The order of the dye-exhaustion level in the cationized fibers having alkyl chain length of 1, 8 and 16 was different with each dye used. The dyed cationized fibers were superior in color fastness to the dyed original cellulosic fiber, whereas the dyed fiber C16 having alkyl chain length of 16 was considerably inferior in color fastness to light and wet rubbing

セルロース繊維のn-alkyl, dimethyl, 3-chloro-2-hydroxypropyl ammonium chloridesによるカチオン化とそれらの抗菌活性について

n-alkyl, dimethyl, 3-chloro-2-hydroxypropyl ammonium chlorides having an alkyl group of different chain lengths were synthesized through the reaction of n-alkyl, dimethylamine hydrochlorides with epichlorohydrin, and used for the cationization of cellulosic fiber. The amount of ammonium chloride in the cationized fibers was estimated from the saturation value of the acid dye using Langmuir\u27s equation. Antibacterial activity of the cationized fiber was studied for the effects of the alkyl chain lengths on the ammonium cation