Immunobiotic feed developed with Lactobacillus delbrueckii subsp. delbrueckii TUA4408L and the soymilk by-product okara improves health and growth performance in pigs

Lactobacillus delbrueckii subsp. delbrueckii TUA4408L is able to differentially modulate the innate immune response of porcine intestinal epithelial cells triggered by TLR4 activation. This strain also has a remarkable ability to grow on plant substrates. These two immunological and biotechnological characteristics prompted us to evaluate whether the soymilk by-product okara fermented with the TUA4408L strain can serve as an immunobiotic feed with the ability to beneficially modulate the intestinal immunity of piglets after weaning to improve their productivity. Our in vivo studies demonstrated that the administration of immunobiotic TUA4408L-fermented okara feed significantly increased piglet growth performance and meat quality. These positive effects were associated with the ability of the TUA4408L-fermented okara feed to beneficially modulate both intestinal microbiota and immunity in pigs. The immunobiotic feed improved the abundance of the beneficial bacteria Lactobacillus and Lactococcus in the gut of pigs, reduced blood markers of inflammation, and differentially regulated the expression of inflammatory and regulatory cytokines in the intestinal mucosa. These findings indicate that the immunobiotic TUA4408L-fermented okara feed could be an economical and environmentally friendly option to improve the growth performance and immune health of pigs.Fil: Suda, Yoshihito. Miyagi University; JapónFil: Sasaki, Nana. Miyagi University; JapónFil: Kagawa, Kyoma. Miyagi University; JapónFil: Elean, Mariano Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; ArgentinaFil: Zhou, Binghui. Tohoku University; JapónFil: Tomokiyo, Mikado. Tohoku University; JapónFil: Islam, Md Aminul. Tohoku University; Japón. Bangladesh Agricultural University; BangladeshFil: Shahid Riaz Rajoka, Muhammad. Tohoku University; JapónFil: Humayun Kober, A.K.M.. Tohoku University; Japón. Chittagong Veterinary and Animal Sciences University; BangladeshFil: Shimazu, Tomoyuki. Miyagi University; JapónFil: Egusa, Shintaro. No especifíca;Fil: Terashima, Yuji. No especifíca;Fil: Aso, Hisashi. Tohoku University; JapónFil: Ikeda Ohtsubo, Wakako. Tohoku University; JapónFil: Villena, Julio Cesar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; ArgentinaFil: Kitazawa, Haruki. Tohoku University; Japó

Osteolytic bone lymphoma

Primary non-Hodgkin bone lymphoma (PBL) can involve solitary or multiple destructive bone lesions such as those of the femur or pelvis humerus, and some cases have osteolytic lesions. PBL is a rare disease in adults. Thus, PBL is rarely considered a differential diagnosis of the osteolytic tumor. In addition, PBL can be underdiagnosed because patients do not experience symptoms or show objective abnormalities in the early stage. Here, we reported an elderly patient with PBL in multiple bones, including the cranial and femoral bones that were fractured due to falling

Effect of Topography on Glossiness and Surface Color for a 5052 Aluminum Alloy * 1

The effect of topography on the glossiness and surface color of aluminum alloy A5052 specimens was experimentally investigated. The surfaces of the specimens were machined using either a vertical milling machine, a horizontal milling machine or a shaping machine. Four specimens were produced by each machine so that the arithmetical mean roughness value, Ra, was less than 1 mm under four different cutting conditions. The experimental results revealed that the vertical and horizontal milling glossiness values were nearly the same, while the glossiness values of the shaped surface was less than half of this value. The surface color of all of the specimens was gray, although the lightness value of the surface color, L Ã , for the horizontal milling surface had the highest value. Based on the experimental results, it was determined that the surface texture of specimens produced by these machines could be characterized by their glossiness and surface color. These results could prove an effective indicator for choosing the most appropriate machining method by providing surface texture values

Ｌａｔａｃｋ コーピング シャクド カイテイバン ノ インシ フヘンセイ ニ カンスル ケントウ

本研究は、Latackコーピング尺度改訂版の因子不変性の検証、ならびに因子得点と基本属性との関連性について検討することを目的とした。調査対象は、岡山県内の特別養護老人ホームに勤務するすべての介護職員とし、調査は施設への留置法で実施した。回収された調査票1,445名のうち、調査項目に欠損値を有さない1,224名の資料を分析に用いた。統計解析には、共分散構造分析による同時因子分析を用い、「調整」と「逃避」の2因子10項目からなる2因子斜交モデルのデータヘの適合度を検討した。その結果、前記因子構造モデルは、性別、年齢、資格の有無、学歴、経験年数、現職場での勤続年数のそれぞれでグループ化された標本間において、すべてのパラメータを拘束した条件下においても、高い水準で適合することを明らかにした。これは、Latackコーピング尺度改訂版の構成概念妥当性を支持するものである。なお基本属性別に因子得点の差の検定を行ったところ、年齢では40歳以上の者は、それ以下の年齢の者に比べて「調整」因子が0.18倍高いこと、また資格のある者は、ない者に比べて「逃避」因子が0.27倍低いことを明らかにした。このことは年齢と資格の有無によって、コーピングの特徴が異なることを示唆するものである。The purpose of this study was to examine the invariability of the revised version of Latack\u27s Coping Questionnarie, we developed. The subject were 1,224 caring professionals at nursing homes for the aged, Okayama prefecture (85 male, 1,139 female), ranging age from 18 to 64. Invariability of the questionnaire was performed with simultaneous factor analyses hold for each of several samples across gender, age, with or without qualifications, educational background, years as care professional, years at present job, using a two-factor (control, escape: 10-item) oblique model. As a results, the models fitted of all condition of the data with equality constraints for all parameters. It showed an invariability and further understanding about the construct validity of the coping questionnaire. Next, factor means were estimated in simultaneous factor analyses in order to clarify relationships between coping and demographic variables. The results indicated that above 40 years old sample was estimated 0.18 units above in control score beside the other. The qualified sample was estimated 0.27 units below in escape score beside the other. These findings represented the characteristics of coping strategy referring to age difference and with or without qualifications