111 research outputs found
Hydraulic loss analysis in a pump-turbine with special emphasis on local rigid vortex and shear
Since the pump as turbine is increasingly employed in energy storage, improving efficiency in both pump and turbine modes is required for economic benefits. This study aims to analyze vortex flow characteristics and vortex control methods in both modes to reduce hydraulic loss. In this paper, a delayed detached eddy simulation was applied in a low specific speed pump-turbine. Based on the entropy production analysis and vorticity binary decomposition in the local vortices, the results show that the local shear is the leading cause of hydraulic loss instead of the existence of vortices. The average wake loss can be 1.6 times higher than the loss in jet regions in pump mode, but there is little difference in the distribution of shear and vortices in the wake flow in turbine mode. The local loss caused by the rotor-stator interaction with a tongue effect at blade passing frequency is up to threefold over the loss without a tongue effect in both modes. Reducing shear and ratio of shear to rigid vorticity of the local vortices via modification in the volute tongue angle to suppress the tongue effect can be an effective way to decrease hydraulic loss in both modes
Assessment of English Teaching From Social - Anthropological Perspective: A Case Study of Microteaching in Warwick SJTU ETD Programme
Microteaching has gained considerable attention for its effectiveness in training teachers. Based on social-anthropological theory, a microteaching workshop in Warwick SJTU ETD Programme for 22 English teachers was investigated. Observation and interview, as the main basic methods, were applied to collect data. The results showed that microteaching offered participants an opportunity to practice teaching and receive useful feedback from peers and professional supervisors. Moreover, it was indicated that the improvement of teaching largely depends on self-reflection. The participants who were aware of teaching objectives and teaching aids, and opened to alternative teaching materials could easily manage the classroom teaching, and activate students’ learning
Experimental Investigation on Motions of Immersing Tunnel Element under Irregular Wave Actions
A concept for autonomous and continuous observation of melt pond morphology: Instrument design and test trail during the 4th CHINARE-Arctic in 2010
Accelerated decline of summer and winter Arctic sea ice has been demonstrated progressively. Melt ponds play a key role in enhancing the feedback of solar radiation in the ice/ocean-atmosphere system, and have thus been a focus of researchers and modelers. A new melt pond investigation system was designed to determine morphologic and hydrologic features, and their evolution. This system consists of three major parts: Temperature-salinity measuring, surface morphology monitoring, and water depth monitoring units. The setup was deployed during the ice camp period of the fourth Chinese National Arctic Research Expedition in summer 2010. The evolution of a typical Arctic melt pond was documented in terms of pond depth, shape and surface condition. These datasets are presented to scientifically reveal how involved parameters change, contributing to better understanding of the evolution mechanism of the melt pond. The main advantage of this system is its suitability for autonomous and long-term observation, over and within a melt pond. Further, the setup is portable and robust. It can be easily and quickly installed, which is most valuable for deployment under harsh conditions
The influence of constitutive law choice used to characterise atherosclerotic tissue material properties on computing stress values in human carotid plaques.
Calculating high stress concentration within carotid atherosclerotic plaques has been shown to be complementary to anatomical features in assessing vulnerability. Reliability of stress calculation may depend on the constitutive laws/strain energy density functions (SEDFs) used to characterize tissue material properties. Different SEDFs, including neo-Hookean, one-/two-term Ogden, Yeoh, 5-parameter Mooney-Rivlin, Demiray and modified Mooney-Rivlin, have been used to describe atherosclerotic tissue behavior. However, the capacity of SEDFs to fit experimental data and the difference in the stress calculation remains unexplored. In this study, seven SEDFs were used to fit the stress-stretch data points of media, fibrous cap, lipid and intraplaque hemorrhage/thrombus obtained from 21 human carotid plaques. Semi-analytic solution, 2D structure-only and 3D fully coupled fluid-structure interaction (FSI) analyses were used to quantify stress using different SEDFs and the related material stability examined. Results show that, except for neo-Hookean, all other six SEDFs fitted the experimental points well, with vessel stress distribution in the circumferential and radial directions being similar. 2D structural-only analysis was successful for all seven SEDFs, but 3D FSI were only possible with neo-Hookean, Demiray and modified Mooney-Rivlin models. Stresses calculated using Demiray and modified Mooney-Rivlin models were nearly identical. Further analyses indicated that the energy contours of one-/two-term Ogden and 5-parameter Mooney-Rivlin models were not strictly convex and the material stability indictors under homogeneous deformations were not always positive. In conclusion, considering the capacity in characterizing material properties and stabilities, Demiray and modified Mooney-Rivlin SEDF appear practical choices for mechanical analyses to predict the critical mechanical conditions within carotid atherosclerotic plaques.This research is supported by BHF PG/11/74/29100, HRUK RG2638/14/16, the NIHR Cambridge Biomedical Research Centre, and National Natural Science Foundation of China (81170291).This is the final version of the article. It first appeared from Elsevier via http://dx.doi.org/10.1016/j.jbiomech.2015.09.02
Metagenomic Insights Into the Contribution of Phages to Antibiotic Resistance in Water Samples Related to Swine Feedlot Wastewater Treatment
In this study, we examined the types of antibiotic resistance genes (ARGs) possessed by bacteria and bacteriophages in swine feedlot wastewater before and after treatment using a metagenomics approach. We found that the relative abundance of ARGs in bacterial DNA in all water samples was significantly higher than that in phages DNA (>10.6-fold), and wastewater treatment did not significantly change the relative abundance of bacterial- or phage-associated ARGs. We further detected the distribution and diversity of the different types of ARGs according to the class of antibiotics to which they confer resistance, the tetracycline resistance genes were the most abundant resistance genes and phages were more likely to harbor ATP-binding cassette transporter family and ribosomal protection genes. Moreover, the colistin resistance gene mcr-1 was also detected in the phage population. When assessing the contribution of phages in spreading different groups of ARGs, β-lactamase resistance genes had a relatively high spreading ability even though the abundance was low. These findings possibly indicated that phages not only could serve as important reservoir of ARG but also carry particular ARGs in swine feedlot wastewater, and this phenomenon is independent of the environment
Highly Efficient Broadband Ambient Energy Harvesting System Enhanced by Meta-Lens for Wirelessly Powering Battery-less IoT Devices
Existing Internet of Things (IoT) devices face a significant challenge in terms of power consumption due to their limited battery life. Capturing and utilizing ambient radio frequency (RF) energy emerges as a promising solution for powering low-power sensors and electronic devices, given its unique spatial and temporal distributions. However, the low level of ambient RF power severely hampers the rectenna’s RF-to-direct current (DC) conversion efficiency, making it incapable of generating sufficient DC power. To address this issue and enhance the conversion efficiency of a broadband rectenna at low environmental power levels, this study introduces a novel technique called the meta-lens assisted technique (MAT). This technique leads to a substantial increase in the rectenna’s received RF power by more than 10 dB. As a result, the total conversion efficiency improves by over 30% across a wide frequency band ranging from 2.9 GHz to 3.63 GHz (with a fractional bandwidth of 22.3%), even when the initial RF power received (without the MAT) was as low as -20 dBm, which approaches the real-life ambient RF power level. Notably, the proposed MAT achieves a 40% to 60% efficiency improvement compared to state-of-the-art approaches. These remarkable results demonstrate the promising potential of the MAT rectenna as an alternative for harvesting low-density wireless energy and supporting low-power-required industrial IoT applications
Recombinant antigen P29 of Echinococcus granulosus induces Th1, Tc1, and Th17 cell immune responses in sheep
Echinococcosis is a common human and animal parasitic disease that seriously endangers human health and animal husbandry. Although studies have been conducted on vaccines for echinococcosis, to date, there is no human vaccine available for use. One of the main reasons for this is the lack of in-depth research on basic immunization with vaccines. Our previous results confirmed that recombinant antigen P29 (rEg.P29) induced more than 90% immune protection in both mice and sheep, but data on its induction of sheep-associated cellular immune responses are lacking. In this study, we investigated the changes in CD4+ T cells, CD8+ T cells, and antigen-specific cytokines IFN-γ, IL-4, and IL-17A after rEg.P29 immunization using enzyme-linked immunospot assay (ELISPOT), enzyme-linked immunosorbent assay (ELISA), and flow cytometry to investigate the cellular immune response induced by rEg.P29 in sheep. It was found that rEg.P29 immunization did not affect the percentage of CD4+ and CD8+ T cells in peripheral blood mononuclear cells (PBMCs), and was able to stimulate the proliferation of CD4+ and CD8+ T cells after immunization in vitro. Importantly, the results of both ELISPOT and ELISA showed that rEg.P29 can induce the production of the specific cytokines IFN-γ and IL-17A, and flow cytometry verified that rEg.P29 can induce the expression of IFN-γ in CD4+ and CD8+ T cells and IL-17A in CD4+ T cells; however, no IL-4 expression was observed. These results indicate that rEg.P29 can induce Th1, Th17, and Tc1 cellular immune responses in sheep against echinococcosis infection, providing theoretical support for the translation of rEg.P29 vaccine applications
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The role of porosity and 3D cross-stent configuration of multiple overlapping uncovered stents in the management of complex aortic aneurysms – insights from haemodynamics
Background: Multiple overlapping uncovered stents (MOUS) have been introduced to manage complex aortic aneurysms with vital branches involvement. It has been shown that the porosity is a key determinant of the treatment outcome. However, the role of 3D cross-stent configuration remains unclear.
Methods: One patient with a complex aortic aneurysm judged not suitable for open surgery nor endovascular repair was invited to participate this study. In total, four bare metal stents were deployed. 3D lesion geometry was reconstructed based on pre- and post-operative CTA, and the zero-pressure configuration was recovered using an inverse procedure. Local haemodynamic parameters, including wall shear stress (WSS), oscillatory shear index (OSI), and particle relative resident time (RRT), as well as the vessel structural stress (VSS), were quantified using one-way fluid-structure interaction (FSI) analysis. In comparison to MOUS, a corresponding compact model was reconstructed by projecting inner layer stents to the most outer layer to form a single layer to eliminate the 3D cross-stent configuration and one-way FSI analysis was performed.
Results: Results obtained showed that the porosity decreased linearly with the number of stents. When the 1st stent was deployed, the mean velocity decreased 36.4% and further reduction of 49.3%, 59.8%, and 62.8% were observed when the 2nd, 3rd and 4th stents were deployed. WSS also decreased with the number of stents deployed, and both OSI and RRT increased, but the increase was very minor with the 4th stent. MOUS deployment induced high VSS concentration in the landing zone while the VSS and pressure in the sac remained nearly unchanged. The compact model yielded a small difference in the value of flow-related parameters and 10%-20% reduction in VSS.
Conclusion: Compared with porosity, the 3D cross-stent of MOUS configuration plays a minor role in the modulation of local haemodynamics. A compact model does not reduce high VSS concentration in the diseased region significantly.This study was supported by British Heart Foundation (BHF) (PG/18/14/33562), Engineering and Physical Sciences Research Council (EPSRC) (EP/P021654/1) and National Institute for Health Research (NIHR) Cambridge Biomedical Research Centre
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