1,387 research outputs found
Introduction to "Law, Politics, and Society in Republican China"
In 2011, the centennial of the 1911 Revolution, the Institute of Modern History of the Chinese Academy of Social Sciences released a set of publications that includes a narrative history of the Republic of China (Zhonghua minguo shi, 12 volumes), a chronology (Dashiji, 12 volumes), and a collection of Republican biographies (Renwuzhuan, 8 volumes). The result of decades of work since the founding of the Institute’s History of the Republic of China unit in 1956, this monumental set pays tribute to the foundational research of multiple cohorts of Chinese historians on the subject of the revolution. Now that many previously accepted “facts” have been more or less tamed, the moment has come, in China as well as elsewhere, for the field to take up the issue of how best to approach the history of the Republic of China from various perspectives
Wu Renshu, Paul Katz, Lin Meili (eds.), Cong chengshi kan Zhongguo de xiandaixing (The city and Chinese modernity)
This richly empirical volume, which grew out of a conference held at the Institute of Modern History of the Academia Sinica, sheds new light on Chinese cities (Beijing, Suzhou, Shanghai, and Chengdu) from the seventeenth to the twentieth centuries. The essays are organised under two headings: “urban life and culture” and “social groupings and urban dynamics.” The volume cuts across the 1839 divide to examine the evolution of consumer culture in pre-modern and modern Chinese cities. It also cu..
Wu Renshu, Paul Katz, Lin Meili (éd.), Cong Chengshi kan Zhongguo de Xiandai xing (La ville et la modernité chinoise)
Cet ouvrage riche en données empiriques, fruit d’une conférence qui s’est tenue à l’Institut d’histoire moderne de l’Academia Sinica, apporte un éclairage nouveau sur les villes chinoises (Pékin, Suzhou, Shanghai et Chengdu) entre le xviie siècle et le xxe siècle. Ces essais sont organisés autour de deux thématiques : « vie et culture urbaines » et « groupes sociaux et dynamiques urbaines ». L’ouvrage, faisant fi de la rupture de 1839, examine l’évolution de la culture consumériste dans les v..
Wu Renshu, Paul Katz, Lin Meili (éd.), Cong Chengshi kan Zhongguo de Xiandai xing (La ville et la modernité chinoise)
Cet ouvrage riche en données empiriques, fruit d’une conférence qui s’est tenue à l’Institut d’histoire moderne de l’Academia Sinica, apporte un éclairage nouveau sur les villes chinoises (Pékin, Suzhou, Shanghai et Chengdu) entre le xviie siècle et le xxe siècle. Ces essais sont organisés autour de deux thématiques : « vie et culture urbaines » et « groupes sociaux et dynamiques urbaines ». L’ouvrage, faisant fi de la rupture de 1839, examine l’évolution de la culture consumériste dans les v..
Introduction to "Rethinking Business History in Modern China"
In this special issue of Cross-Currents, the contributing authors look at how business linked China and the world from the mid-nineteenth to the mid-twentieth century, and how Chinese and foreign companies interacted with one another, as well as with political power, long before today. Some authors concentrate on material connections, including shipping, banking, the building of railroads, the spread of the motion picture industry, international treaties, and the formation of knowledge, while others investigate the role of business culture and how entrepreneurship and networks of trust crossed borders. Both of these aspects are set against the backdrop of simultaneous Chinese state-building efforts that became evident in the state creation of a national market and the formation of political borders. All of the authors collected here draw on case studies of individual entrepreneurs or companies, just as they draw on the new historical and theoretical scholarship summarized above to fill out the picture of China’s economic development within global processes. As the contributions to this issue demonstrate, rethinking Chinese business history also forces us to rethink Chinese urban history more generally... The new pictures of business practice presented here entail a remapping of the spatial dynamics of such activities and thereby a new understanding of the making of urban China..
MAAIG: Motion Analysis And Instruction Generation
Many people engage in self-directed sports training at home but lack the
real-time guidance of professional coaches, making them susceptible to injuries
or the development of incorrect habits. In this paper, we propose a novel
application framework called MAAIG(Motion Analysis And Instruction Generation).
It can generate embedding vectors for each frame based on user-provided sports
action videos. These embedding vectors are associated with the 3D skeleton of
each frame and are further input into a pretrained T5 model. Ultimately, our
model utilizes this information to generate specific sports instructions. It
has the capability to identify potential issues and provide real-time guidance
in a manner akin to professional coaches, helping users improve their sports
skills and avoid injuries.Comment: Accepted to the ACM Multimedia Asia 2023 Workshop on Intelligent
Sports Technologies (WIST
Single-crystalline δ-Ni2Si nanowires with excellent physical properties
[[abstract]]In this article, we report the synthesis of single-crystalline nickel silicide nanowires (NWs) via chemical vapor deposition method using NiCl2·6H2O as a single-source precursor. Various morphologies of δ-Ni2Si NWs were successfully acquired by controlling the growth conditions. The growth mechanism of the δ-Ni2Si NWs was thoroughly discussed and identified with microscopy studies. Field emission measurements show a low turn-on field (4.12 V/μm), and magnetic property measurements show a classic ferromagnetic characteristic, which demonstrates promising potential applications for field emitters, magnetic storage, and biological cell separation.[[notice]]補正完畢[[incitationindex]]SCI[[booktype]]電子版[[booktype]]紙
The impact of luxury housing on neighborhood housing prices: an application of the spatial difference-in-differences method
This study investigated the spatial spillover effects of luxury housing during and after construction, in regards to increases in housing prices in neighboring areas as well as the spatial dependence of neighboring housing. This study focused on already completed luxury housing in Taipei, Taiwan. First, the nearest-neighbor matching approach of propensity score matching was used to overcome the problem of data heterogeneity. The difference-in-differences (DD) method and spatial econometrics were used for analysis. The empirical results indicated that the spatial error model had the best goodness of fit. This indicated that housing prices increased by 13.0% during construction of luxury housing nearby. This indicated that housing prices increased by 5.8% after the construction of luxury housing nearby. The empirical results showed that the ongoing and completed construction of luxury housing had spillover effects on housing prices. The effect of ongoing construction of luxury housing was particularly large in scope, indicating its role as a predictor of psychological reaction in the market
Association between use of non–vitamin k oral anticoagulants with and without concurrent medications and risk of major bleeding in nonvalvular atrial fibrillation
Importance: Non–vitamin K oral anticoagulants (NOACs) are commonly prescribed with other medications that share metabolic pathways that may increase major bleeding risk.
Objective: To assess the association between use of NOACs with and without concurrent medications and risk of major bleeding in patients with nonvalvular atrial fibrillation.
Design, Setting, and Participants: Retrospective cohort study using data from the Taiwan National Health Insurance database and including 91 330 patients with nonvalvular atrial fibrillation who received at least 1 NOAC prescription of dabigatran, rivaroxaban, or apixaban from January 1, 2012, through December 31, 2016, with final follow-up on December 31, 2016.
Exposures: NOAC with or without concurrent use of atorvastatin; digoxin; verapamil; diltiazem; amiodarone; fluconazole; ketoconazole, itraconazole, voriconazole, or posaconazole; cyclosporine; erythromycin or clarithromycin; dronedarone; rifampin; or phenytoin.
Main Outcomes and Measures: Major bleeding, defined as hospitalization or emergency department visit with a primary diagnosis of intracranial hemorrhage or gastrointestinal, urogenital, or other bleeding. Adjusted incidence rate differences between person-quarters (exposure time for each person during each quarter of the calendar year) of NOAC with or without concurrent medications were estimated using Poisson regression and inverse probability of treatment weighting using the propensity score.
Results: Among 91 330 patients with nonvalvular atrial fibrillation (mean age, 74.7 years [SD, 10.8]; men, 55.8%; NOAC exposure: dabigatran, 45 347 patients; rivaroxaban, 54 006 patients; and apixaban, 12 886 patients), 4770 major bleeding events occurred during 447 037 person-quarters with NOAC prescriptions. The most common medications co-prescribed with NOACs over all person-quarters were atorvastatin (27.6%), diltiazem (22.7%), digoxin (22.5%), and amiodarone (21.1%). Concurrent use of amiodarone, fluconazole, rifampin, and phenytoin with NOACs had a significant increase in adjusted incidence rates per 1000 person-years of major bleeding than NOACs alone: 38.09 for NOAC use alone vs 52.04 for amiodarone (difference, 13.94 [99% CI, 9.76-18.13]); 102.77 for NOAC use alone vs 241.92 for fluconazole (difference, 138.46 [99% CI, 80.96-195.97]); 65.66 for NOAC use alone vs 103.14 for rifampin (difference, 36.90 [99% CI, 1.59-72.22); and 56.07 for NOAC use alone vs 108.52 for phenytoin (difference, 52.31 [99% CI, 32.18-72.44]; P < .01 for all comparisons). Compared with NOAC use alone, the adjusted incidence rate for major bleeding was significantly lower for concurrent use of atorvastatin, digoxin, and erythromycin or clarithromycin and was not significantly different for concurrent use of verapamil; diltiazem; cyclosporine; ketoconazole, itraconazole, voriconazole, or posaconazole; and dronedarone.
Conclusions and Relevance: Among patients taking NOACs for nonvalvular atrial fibrillation, concurrent use of amiodarone, fluconazole, rifampin, and phenytoin compared with the use of NOACs alone, was associated with increased risk of major bleeding. Physicians prescribing NOAC medications should consider the potential risks associated with concomitant use of other drugs
Gfi-1 is the transcriptional repressor of SOCS1 in acute myeloid leukemia cells
ABSTRACT Silencing of SOCS1, a TSG, has been detected in various malignancies, including AML. However, the underlying mechanism of SOCS1 inactivation remains elusive. In this study, we explored the role of histone methylation in SOCS1 expression in AML cells. By ChIP assay, we demonstrated that G9a and SUV39H1, two enzymes catalyzing H3K9 methylation, were physically associated with the SOCS1 promoter, and treatment with chaetocin, a histone methyltransferase inhibitor, suppressed H3K9 methylation on the SOCS1 promoter and enhanced SOCS1 expression. Furthermore, knockdown of G9a and SUV39H1 by siRNA could also induce SOCS1 expression. On the other hand, SOCS1 knockdown by shRNA eliminated chaetocin-induced cell apoptosis. To investigate further whether any transcription factor was involved in H3K9 methylation-related SOCS1 repression, we scanned the sequences of the SOCS1 gene promoter and found two binding sites for Gfi-1, a transcription repressor. By DNA pull-down and ChIP assays, we showed that Gfi-1 directly bound the SOCS1 promoter, and ectopic Gfi-1 expression suppressed STAT5-induced SOCS1 promoter activation. In contrast, Gfi-1 knockdown by shRNA enhanced SOCS1 expression and inhibited STAT5 expression. Moreover, the knockdown of G9a completely rescued the repressive effect of Gfi-1 on STAT5A-induced SOCS1 promoter activation. Collectively, our study indicates that the expression of Gfi-1 contributes to SOCS1 silencing in AML cells through epigenetic modification, and suppression of histone methyltransferase can provide new insight in AML therapy. J. Leukoc. Biol. 95: 000 -000; 2014
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