Formation of artificial granules for proving gelation as the main mechanism of aerobic granulation in biological wastewater treatment

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Narrowband Single-Pole Double-Throw Filtering Switch Based on Dielectric Resonator

© 2001-2012 IEEE. In this letter, a narrowband single-pole double-throw (SPDT) filtering switch based on dielectric resonators (DRs) is presented. It consists of two DRs shared by two channels for size reduction. Printed circuit boards are embedded in the metal cavity to integrate the PIN diodes. The switching between two channels is enabled by controlling the PIN diodes connected to the two output feeding lines. The electromagnetic field distributions of the DR at the TE -{11\delta } mode are studied to control the coupling between the DR and two output feeding lines. When one channel is on, the PIN diode for this channel is turned off, which does not introduce loss and affect the linearity. For the off-state channel, isolation is obtained by controlling the coupling between the DR and output feeding line, which is considerably enhanced. For demonstration, the DR filtering SPDT switch is implemented. The measured results exhibit that the proposed filtering SPDT switch has narrow bandwidth, low loss, high isolation, and high linearity

The association of HBV core promoter double mutations (A1762T and G1764A) with viral load differs between HBeAg positive and anti-HBe positive individuals: A longitudinal analysis

Background/Aims: Although there have been a few reports regarding the effect of basal core promoter (BCP) double mutations (A1762T and G1764A) on hepatitis B viral loads, the association remains uncertain. We aim to determine the association after controlling for HBeAg - a strong confounding factor.Methods: We selected randomly 190 individuals from a Chinese cohort of 2258 subjects for cross-sectional analysis and 56 of the 190 for longitudinal analysis of viral loads.Results: In multivariable analysis of the cross-sectional data, BCP double mutations are significantly associated with lower viral loads in HBeAg positive subjects but no difference was found in anti-HBe positive subjects. Triple mutations at nucleotide (nt) 1753, 1762 and 1764 and mutations between nt 1809 and 1817, precore stop mutation (nt 1896) and genotype are not associated with viral loads in either HBeAg or anti-HBe positive subjects. Analysis of the longitudinal data yielded similar results to the cross-sectional data. Viral loads differ significantly between individuals infected with wild-type and BCP double mutations prior to HBeAg seroconversion but this difference is lost after seroconversion.Conclusions: BCP double mutations are associated with lower viral loads in HBeAg positive individuals but have no effect on the viral loads of anti-HBe positive individuals. (C) 2008 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved

Unsupervised visual domain adaptation via dictionary evolution

© 2016 IEEE. In real-word visual applications, distribution mismatch between samples from different domains may significantly degrade classification performance. To improve the generalization capability of classifier across domains, domain adaptation has attracted a lot of interest in computer vision. This work focuses on unsupervised domain adaptation which is still challenging because no labels are available in the target domain. Most of the attention has been dedicated to seeking domain-invariant feature by exploring the shared structure between domains, ignoring the valuable discriminative information contained in the labeled source data. In this paper, we propose a Dictionary Evolution (DE) approach to construct discriminative features robust to domain shift. Specifically, DE aims to adapt a discriminative dictionary learnt based on labeled source samples to unlabeled target samples through a gradual transition process. We show that the learnt dictionary is endowed with cross-domain data representation ability and powerful discriminant capability. Empirical results on real world data sets demonstrate the advantages of the proposed approach over competing methods

Highly reproducible SERS substrate based on polarization-free Ag nanoparticles decorated SiO2/Si core-shell nanowires array

SiO2/Si core-shell nanowires array coated with gap-rich silver nanoparticles were demonstrated as a highly reproducible surface-enhanced Raman scattering (SERS) substrate. SERS detection of a relative standard deviation of 8% for 10−4 M R6G with a spot size of ∼2 μm and 900 spots over an area of 150 × 150 μm2 was reported. The high reproducibility is ascribed to the polarization-independent electrical field distribution among three-dimensional nanowire structure with an optimized thickness of SiO2 shell layer.published_or_final_versio

Weak sharp minima for semi-infinite optimization problems with applications

2007-2008 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe

Nanofibers Fabricated Using Triaxial Electrospinning as Zero Order Drug Delivery Systems

A new strategy for creating functional trilayer nanofibers through triaxial electrospinning is demonstrated. Ethyl cellulose (EC) was used as the filament-forming matrix in the outer, middle, and inner working solutions and was combined with varied contents of the model active ingredient ketoprofen (KET) in the three fluids. Triaxial electrospinning was successfully carried out to generate medicated nanofibers. The resultant nanofibers had diameters of 0.74 ± 0.06 μm, linear morphologies, smooth surfaces, and clear trilayer nanostructures. The KET concentration in each layer gradually increased from the outer to the inner layer. In vitro dissolution tests demonstrated that the nanofibers could provide linear release of KET over 20 h. The protocol reported in this study thus provides a facile approach to creating functional nanofibers with sophisticated structural features

Reconfigurable Intelligent Surface Assisted MEC Offloading in NOMA-Enabled IoT Networks

Integrating mobile edge computing (MEC) into the Internet of Things (IoT) enables resource-limited mobile terminals to offload part or all of the computation-intensive applications to nearby edge servers. On the other hand, by introducing reconfigurable intelligent surface (RIS), it can enhance the offloading capability of MEC, such that enabling low latency and high throughput. To enhance the task offloading, we investigate the MEC non-orthogonal multiple access (MEC-NOMA) network framework for mobile edge computation offloading with the assistance of a RIS. Different from conventional communication systems, we aim at allowing multiple IoT devices to share the same channel in tasks offloading process. Specifically, the joint consideration of channel assignments, beamwidth allocation, offloading rate and power control is formulated as a multi-objective optimization problem (MOP), which includes minimizing the offloading delay of computing-oriented IoT devices (CP-IDs) and maximizing the transmission rate of communication-oriented IoT devices (CM-IDs). Since the resulting problem is non-convex, we employ ϵ-constraint approach to transform the MOP into the single-objective optimization problems (SOP), and then the RIS-assisted channel assignment algorithm is developed to tackle the fractional objective function. Simulation results corroborate the benefits of our strategy, which can outperforms the other benchmark schemes

IDS mutation in a Chinese MPS II patient Case report

Background: Mucopolysaccharidosis type II (MPS II; also known as Hunter syndrome) is an X-linked multisystem disorder resulting from the defective activity of the enzyme iduronate-2-sulfatase (IDS). Genetic testing is crucial in clarifying and diagnosing different types of MPS diseases. In this paper we report a novel IDS nonsense mutation resulting in MPS II in several patients from a Chinese family. Methods: IDS enzyme activity, polymerase chain reaction, and DNA sequencing were performed to confirm the diagnosis of MPS II. Results: Three patients had no detectable IDS activity. Two genetic tests revealed a novel IDS nonsense mutation (c.1030G>T, p.E344X) inherited from their mothers. The nonsense mutation shortened the peptide chain from 550 to 344 amino acids, which is believed to be a disease-causing mutation. Conclusions: MPS II is inherited in an X-linked manner. The risk to sibs depends on the carrier status of the mother. Genetic testing is necessary to identify disease-causing mutation. With this information, carrier testing for at-risk female relatives and prenatal testing for pregnancies at increased risk become possible. World J Pediatr 2012;8(3):281-28