HISTOPATHOLOGICAL STUDIES ON BOVINE MAMMARY GLAND II. : TISSUE REACTION TO MICROSCOPICAL PSEUDOCONCREMENT

Neither the nature of microscopical pseudoconcrements nor their genesis were intended for detailed discussion in this paper. If findings pertaining to such problems are required based on microscopical investigation, differences of incidence depending on location need to be clearly describe in a larger number of cases. Authors' direct purpose lay in discussing the various responses of mammary gland tissue to the pseudoconcrement. Therefore, it should not be expected that their discussion would be of assistance in solving the opposite opinions held by E. JOEST and W. STECK, and MCFADYEAN. The present author would like to point out that the cause of different opinions might be traced to neglect in taking into consideration the differences in the materials investigated. While MCFADYEAN selected fairly normal mammary gland as the material for his investigation, JOEST and STECK used the pseudoconcrements in pathological mammary gland for their investigation at least judging from their figures. It is obvious that the results of the present authors' research make it possible for them to say a pseudoconcrement is an endogenous foreign body which normally is proved to be located in the lumen of acinus. In this connection, a problem lies in JOEST and STECK'S research in that the material is limited to the pseudoconcrement which predominates in epithelial layer or stands on the wall of acinus and duct. On the contrary, MCFADYEAN did not seem to pay much attention to the appearance of pseudoconcrement in the tissue regardless of parenchyma and interstitium. It can be interpreted that the opposition in reports of the early authors has resulted from the materials used. The materials of the present investigation are the cases of mastitis circumscripta and mastitis diffusa reported in the first paper. The results of this investigation can be summarized as follows. 1. It can be said without doubt that the pseudoconcrement is produced in the lumen of acinus. 2. Importance should be attached to the histological features of the epithelium which envelops the pseudoconcrement which is proved to be attaching to the wall of acinus and duct, particularly in the lumen of the latter, 3. The pseudoconcrements which occurred in ductal epithelium and were embedded in interstitium show passive tissue reaction. 4. The authors wonder why not they can say that such histological findings can be resulted from the nature of acinar and ductal epithelia, particularly of the latter. The authors are of opinion that the tendency of the characteristics of the epithelial layer in inflammatory mammary gland tissue to envelop and absorb foreign body should be emphasized

HISTOPATHOLOGICAL STUDIES ON BOVINE MAMMARY GLAND I : HISTOLOGICAL FINDINGS OF MASTITIS

In this paper there are described patho-histological findings on thirty cases of bovine mastitis. Further discussion is offered. As a result of this examination, the writers place emphasis on two-way inflammatory tissue reactions which exist in bovine mammary glands. At the same time they also pay special attention to the types of mastitis of which the foci were located in the acinar tissue of acini, lobules and groups of lobules

PATHOLOGICAL STUDIES OF AVIAN LEUKOSIS : I. ON PATHOGENESIS OF AVIAN VISCERAL LYMPHOMATOSIS

There is no doubt that all of the cases just described, from the findings, are suffered from avian visceral lymphomatosis. The microscopical findings which were observed in all the present cases may be summarized as follows : Hyperplasia of the lymphatic tissue a."Abnormal hyperplasia" of the lymphatic tissue b."Immaturation" c."Maturation"[d. Lymphatic tissue outside the question] In the first place, the authors will explain the terms used."Abnormal hyperplasia" of the lymphatic tissue This is hyperplasia of the lymphatic tissues in which the principal cellular element was composed of large-pale-nuclear cells repeatedly called in the preceding descriptions. The cells was not identical with lymphoblasts, and the authors consider that the cells may be appropriately called germ cells in the lymphatic tissues. The cells of this kind have frequently been called lymphoid cells in the literature (v. discussion)."Immaturation" and "Maturation" Both terms indicate such histological features as the abnormally hyperplastic lymphatic tissues were composed of large-pale-nuclear cells and had a neoplastic character. In "maturation", it is characteristic that the hyperplastic tissues show histological features suggestive of the lymph follicles (v. discussion). Next, the authors illustrate the findings in the three groups. In group 1 (Chart 1) which includes 123 cases, 6 were cases of "abnormal hyperplasia" of the lymphatic tissues, which were only in the chicken stage. Two cases of "immaturation" and one of "maturation" were detected only in the adult stage. In the final experimental phase, no abnormal cases were detected. In general, the same tendency could be also observed in groups 2 and 3 (Charts 2 and 3). From all of the cases illustrated, also, one case of neural lymphomatosis from the December cases of group 1,one case of erythroblastosis from the June cases in the terminal phase of the experiment in group 2,and two cases of neural lymphomatosis from the October cases of group 3 were also detected. Other than these, there were no remarkable infectious diseases in cases which died or were killed by reason of accidents

HISTOPATHOLOGICAL STUDIES ON BOVINE MAMMARY GLAND III ON THE "ACTINOMYCOTIC" UDDER

In recent years, in view of the fact that reports on granulomatous staphylococcal mastitis are rare, in the present paper as to the mammary glands of 7 cases indiscriminately collected from meat packing plant meterials, report was performed on the disease from the viewpoint of histopathology