Comparison of 2.2mm micro incision and 3.0mm incision coaxial phacoemulsification

AIM:To compare the operation effect of 2.2mm micro incision and 3.0mm incision coaxial phacoemulsification.<p>METHODS: Patients with age-related cataract(90 cases, 90 eyes)were enrolled in the study from January 2012 to June 2013 in our hospital, and they were randomly divided into 2 groups: 2.2mm incision group(45 eyes of 45 cases), 3.0mm incision group(45 eyes of 45 cases). Corneal tunnel incision coaxial phacoemulsification was performed. At 1d, 1wk, 1, 3mo after operation, the visual acuity, corneal endothelial cell count, central corneal thickness, operation astigmatism were recorded.<p>RESULTS: One day after operation, the visual acuity of 2.2mm incision group were significantly improved, the difference was statistically significant(<i>P</i><0.05), there were no differences in two groups at 1wk, 1, 3mo after operation. No significant differences between the two groups of corneal endothelial cell counting, central corneal thickness at 1wk, 1, 3mo after operation were observed(<i>P</i>>0.05). Operation source astigmatism had statistically significant difference at 1d, 1wk, 1, 3mo after operation(<i>P</i><0.05), it decreased significantly in the 2.2mm incision group. <p>CONCLUSION: The 2.2mm small incision coaxial phacoemulsification with postoperative visual acuity improved more significantly, can significantly reduce the operation astigmatism

MiR-148a inhibits angiogenesis by targeting ERBB3.

MicroRNAs (miRNAs) play an important role in carcinogenesis in various solid cancers including breast cancer. Down-regulation of microRNA-148a (miR-148a) has been reported in certain cancer types. However, the biological role of miR-148a and its related targets in breast cancer are unknown yet. In this study, we showed that the level of miR-148a was lower in MCF7 cells than that in MCF10A cells. V-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (ERBB3) is a direct target of miR-148a in human breast cancer cells through direct binding of miR-148a to ERBB3 3\u27-UTR region. Overexpression of miR-148a in MCF7 cells inhibited ERBB3 expression, blocked the downstream pathway activation including activation of AKT, ERK1/2, and p70S6K1, and decreased HIF-1α expression. Furthermore, forced expression of miR-148a attenuated tumor angiogenesis in vivo. Our results identify ERBB3 as a direct target of miR-148a, and provide direct evidence that miR-148a inhibits tumor angiogenesis through ERBB3 and its downstream signaling molecules. This information would be helpful for targeting the miR-148a/ERBB3 pathway for breast cancer prevention and treatment in the future

Study on key technologies of energy-saving and environment-protective pumps

To meet energy-saving and environment-protective purpose, a series of plastic pumps are developed by composite molding. There are four key techniques involved, firstly, plastic hydraulic components with light-weight; secondly, steel barrel as a pump casing and a connection component as well; thirdly, floating impeller strategy where impeller is drifting freely along shaft; and lastly, a self balancing impeller technique which can totally keep axial force balancing. The manufacturing process is energy-saving, and the components can be recycled, which have great potentials for conservation of environment

Tunable multiband directional electromagnetic scattering from spoof Mie resonant structure

We demonstrate that directional electromagnetic scattering can be realized from a artificial Mie resonant strcuture which supports electric and magnetic dipole modes simultaneously. The directivity of the far-field radiation pattern can be switched by changing the incident light wavelength as well as tailoring the geometric parameters of the structure. Particularly, the electric quadrupole at higher frequency contribute significantly to the scattered fields, leading to enhancement of the directionality. In addition, we further design a quasiperiodic spoof Mie resonant structure by alternately inserting two materials into the slits. The results show that multi-band directional light scattering are realized by exciting multiple electric and magnetic dipole modes with different frequencies in the quasiperiodic structure. The presented design concept is general from microwave to terahertz region and can be applied for various advanced optical devices, such as antenna, metamaterial and metsurface.Comment: 10pages,6figure

Differentiation between tuberculosis and leukemia in abdominal and pelvic lymph nodes: evaluation with contrast-enhanced multidetector computed tomography

PURPOSE: To compare the characteristics of tubercular vs. leukemic involvement of abdominopelvic lymph nodes using multidetector computed tomography (CT). MATERIALS AND METHODS: We retrospectively reviewed multidetector computed tomography features including lymph node size, shape, enhancement patterns, and anatomical distribution, in 106 consecutive patients with newly diagnosed, untreated tuberculosis (55 patients; 52%) or leukemia (51 patients; 48%). In patients with leukemia, 32 (62.7%) had chronic lymphocytic leukemia, and 19 (37.3%) had acute leukemias; of these, 10 (19.6%) had acute myeloid leukemia, and 9 (17.6%) had acute lymphocytic leukemia. RESULTS: The lower para-aortic (30.9% for tuberculosis, 63.2% for acute leukemias and 87.5% for chronic lymphocytic leukemia) and inguinal (9.1% for tuberculosis, 57.9% for acute leukemias and 53.1% for chronic lymphocytic leukemia) lymph nodes were involved more frequently in the three types of leukemia than in tuberculosis (both with

Robust stability conditions for remote SISO DMC controller in networked control systems

A two level hierarchy is employed in the design of Networked Control Systems (NCSs) with bounded random transmission delay. At the lower level a local controller is designed to stabilize the plant. At the higher level a remote controller with the Dynamic Matrix Control (DMC) algorithm is implemented to regulate the desirable set-point for the local controller. The conventional DMC algorithm is not applicable due to the unknown transmission delay in NCSs. To meet the requirements of a networked environment, a new remote DMC controller is proposed in this study. Two methods, maximum delayed output feedback and multi-rate sampling, are used to cope with the delayed feedback sensory data. Under the assumption that the closed-loop local system is described by one FIR model of an FIR model family, the robust stability problem of the remote DMC controller is investigated. Applying Jury's dominant coefficient lemma and some stability results of switching discrete-time systems with multiple delays; several stability criteria are obtained in the form of simple inequalities. Finally, some numerical simulations are given to demonstrate the theoretical results