Impact of high-frequency pumping on anomalous finite-size effects in three-dimensional topological insulators

Lowering of the thickness of a thin-film three-dimensional topological insulator down to a few nanometers results in the gap opening in the spectrum of topologically protected two-dimensional surface states. This phenomenon, which is referred to as the anomalous finite-size effect, originates from hybridization between the states propagating along the opposite boundaries. In this work, we consider a bismuth-based topological insulator and show how the coupling to an intense high-frequency linearly polarized pumping can further be used to manipulate the value of a gap. We address this effect within recently proposed Brillouin-Wigner perturbation theory that allows us to map a time-dependent problem into a stationary one. Our analysis reveals that both the gap and the components of the group velocity of the surface states can be tuned in a controllable fashion by adjusting the intensity of the driving field within an experimentally accessible range and demonstrate the effect of light-induced band inversion in the spectrum of the surface states for high enough values of the pump.Comment: 6 pages, 3 figure

Lymphotoxin Alpha (<i>LTA</i>) Polymorphism Is Associated with Prognosis of Non-Hodgkin’s Lymphoma in a Chinese Population

<div><p>Background</p><p>Non-Hodgkin’s lymphoma (NHL) has been widely reported to be associated with autoimmune and pro-inflammatory response, and genetic polymorphisms of candidate genes involved in autoimmune and pro-inflammatory response may influence the survival and prognosis of NHL patients. To evaluate the role of such genetic variations in prognosis of NHL, we conducted this study in a Chinese population.</p><p>Methods</p><p>We used the TaqMan assay to genotype six single nucleotide polymorphisms (SNPs) (<i>TNF</i> rs1799964T>C, <i>LTA</i> rs1800683G>A, <i>IL-10</i> rs1800872T>G, <i>LEP</i> rs2167270G>A, <i>LEPR</i> rs1327118C>G, <i>TNFAIP8</i> rs1045241C>T) for 215 NHL cases. Kaplan-Meier analysis was performed to compare progression free survival among two common genotypes. Cox proportional hazard models were used to identify independent risk factors.</p><p>Results</p><p>We observed that <i>LTA</i> rs1800683G>A was significantly associated with risk of progression or relapse in NHL patients (HR = 1.63, 95%CI = 1.06–2.51; <i>P</i> = 0.028), particularly in Diffuse large B cell lymphoma (DLBCL) cases (HR = 1.50, 95%CI = 1.10–2.04, <i>P</i> = 0.01). Both univariate and multivariate Cox regression analysis showed that in DLBCL patients, Ann Arbor stage III/IV, elevated LDH level before treatment and <i>LTA</i> rs1800683 AA genotype carrier were independent risk factors for progression or relapse. While in NK/T cell lymphoma, Ann Arbor stage III/IV and elevated β₂-MG level before treatment indicated poorer prognosis.</p><p>Conclusions</p><p>The polymorphism of <i>LTA</i> rs1800683G>A contributes to NHL prognosis in a Chinese population. Further large-scale and well-designed studies are needed to confirm these results.</p></div

Clinical characteristics of 215 NHL cases.

<p>Clinical characteristics of 215 NHL cases.</p

Univariate and multivariate analysis for PFS in DLBCL cases.

<p>Univariate and multivariate analysis for PFS in DLBCL cases.</p

Univariate and multivariate analysis for PFS in NK/T-cell lymphoma cases.

<p>Univariate and multivariate analysis for PFS in NK/T-cell lymphoma cases.</p

Histopathologic features of ALK-positive diffuse large B cell lymphoma.

<p>(haematoxylin & eosin). A: Medium- to large-sized cells with prominent nucleoli B: Sinusoidal Invasion C: plasmablastic/immunoblastic differentiation D: Multinucleated giant neoplastic cells E: Focal necrosis F: frequent mitosis.</p

Clinical information and follow up data of 17 patients.

<p>Clinical information and follow up data of 17 patients.</p

s1.docx, s2.dox Xiang-Nan Jiang

Primers for the detection of ALK fusion transcripts and <b>summary of immunohistochemical findings</b

Optimization of Functional Blocks of Organic Ligands Regulating the Electrocatalytic Hydrogen Evolution Reaction of Co(II)- or Ni(II)-Based Organic Frameworks/Nickel Foam Composites

The design of efficient and ultradurable hydrogen evolution reaction (HER) electrocatalysts is very important to the development of a green hydrogen economy. Herein, three examples of metal–organic frameworks (MOFs) with similar structures were designed and synthesized by adjusting the functional blocks in the structures of organic ligands. On the basis of the self-supporting material formed by these MOFs and nickel foam, we phosphated them to obtain heterojunction catalysts. Different functional blocks in the ligands have different effects on the phosphating process and thus yield different heterojunction structures. Due to the synergistic action of NiP and Ni5P4, a high catalytic performance was achieved. This work provides a theoretical direction for the study of the structure–activity relationship and the synthesis of efficient HER catalysts

Summary of the clinicopathologic fueatures of the ALK+, LBCL cases of our study and the reviewed literatures.

<p>Summary of the clinicopathologic fueatures of the ALK+, LBCL cases of our study and the reviewed literatures.</p