Current perspectives on cell-assisted lipotransfer for breast cancer patients after radiotherapy

Abstract Background Cell-assisted lipotransfer (CAL), a technique of autologous adipose transplantation enriched with adipose-derived stem cells (ADSCs), has the potential to improve cosmetic outcomes at irradiated sites. However, many concerns have been raised about the possibility of ADSCs increasing oncological risk in cancer patients. With the increasing demand for CAL reconstruction, there is an urgent need to determine whether CAL treatment could compromise oncological safety after radiotherapy, as well as to evaluate its efficacy in guiding clinical decisions. Methods A PRISMA-compliant systematic review of the safety and efficacy of CAL in breast cancer patients after radiotherapy was conducted. The PubMed, Ovid, Cochrane Library, and ClinicalTrials.gov databases were comprehensively searched from inception to 31 December 2021. Results The search initially yielded 1185 unique studies. Ultimately, seven studies were eligible. Based on the limited outcome evidence, CAL did not increase recurrence risk in breast cancer patients but presented aesthetic improvement and higher volumetric persistence in a long-term follow-up. Although breast reconstruction with CAL also had oncological safety after radiotherapy, these patients needed more adipose tissue and had relatively lower fat graft retention than the non-irradiated patients (P < 0.05). Conclusions CAL has oncological safety and does not increase recurrence risk in irradiated patients. Since CAL doubles the amount of adipose required without significantly improving volumetric persistence, clinical decisions for irradiated patients should be made more cautiously to account for the potential costs and aesthetic outcomes. There is limited evidence at present; thus, higher-quality, evidence-based studies are required to establish a consensus on breast reconstruction with CAL after radiotherapy

Optical Bloch oscillations and Zener tunneling of Airy beams in ionic-type photonic lattices

<p> We report on the existence of optical Bloch oscillations (OBOs) and Zener tunneling (ZT) of Airy beams in ionic-type photonic lattices with a refractive index ramp. Different from their counterparts in uniform lattices, Airy beams undergoing OBOs show an alternatively switched concave and convex trajectory as well as a periodical revival of input beam profiles. Moreover, the ionic-type photonic lattice established in photorefractive crystal exhibits a reconfigurable lattice structure, which provides a flexible way to tune the amplitude and period of the OBOs. Remarkably, it is demonstrated that the band gap of the lattice can be readily controlled by rotating the lattice inducing beam, which forces the ZT rate to follow two significant different decay curves amidst decreasing index gradient. Our results open up new possibilities for all-optical switching, routing and manipulation of Airy beams. (C) 2016 Optical Society of America</p

Novel fluorescent sequence-related amplified polymorphism(FSRAP) markers for the construction of a genetic linkage map of wheat(Triticum aestivum L.)

Novel fluorescent sequence-related amplified polymorphism (FSRAP) markers were developed based on the SRAP molecular marker. Then, the FSRAP markers were used to construct the genetic map of a wheat (Triticum aestivumL.) recombinant inbred line population derived from a Chuanmai 42×Chuannong 16 cross. Reproducibility and polymorphism tests indicated that the FSRAP markers have repeatability and better reflect the polymorphism of wheat varieties compared with SRAP markers. A total of 430 polymorphic loci between Chuanmai 42 and Chuannong 16 were detected with 189 FSRAP primer combinations. A total of 281 FSARP markers and 39 SSR markers re classified into 20 linkage groups. The maps spanned a total length of 2499.3cM with an average distance of 7.81cM between markers. A total of 201 markers were mapped on the B genome and covered a distance of 1013cM. On the A genome, 84 markers were mapped and covered a distance of 849.6cM. On the D genome, however, only 35 markers were mapped and covered a distance of 636.7cM. No FSRAP markers were distributed on the 7D chromosome. The results of the present study revealed that the novel FSRAP markers can be used to generate dense, uniform genetic maps of wheat

Visualization 1: Optical Bloch oscillations and Zener tunneling of Airy beams in ionic-type photonic lattices

Optical Bloch oscillations of Airy beam in lattice 1 Originally published in Optics Express on 08 August 2016 (oe-24-16-18332

Visualization 2: Optical Bloch oscillations and Zener tunneling of Airy beams in ionic-type photonic lattices

Optical Bloch oscillations of Airy beam in lattice 2 Originally published in Optics Express on 08 August 2016 (oe-24-16-18332

Generating Salt-Affected Irrigated Cropland Map in an Arid and Semi-Arid Region Using Multi-Sensor Remote Sensing Data

Soil salinization is a widespread environmental hazard and a major abiotic constraint affecting global food production and threatening food security. Salt-affected cropland is widely distributed in China, and the problem of salinization in the Hetao Irrigation District (HID) in the Inner Mongolia Autonomous Region is particularly prominent. The salt-affected soil in Inner Mongolia is 1.75 million hectares, accounting for 14.8% of the total land. Therefore, mapping saline cropland in the irrigation district of Inner Mongolia could evaluate the impacts of cropland soil salinization on the environment and food security. This study hypothesized that a reasonably accurate regional map of salt-affected cropland would result from a ground sampling approach based on PlanetScope images and the methodology developed by Sentinel multi-sensor images employing the machine learning algorithm in the cloud computing platform. Thus, a model was developed to create the salt-affected cropland map of HID in 2021 based on the modified cropland base map, valid saline and non-saline samples through consistency testing, and various spectral parameters, such as reflectance bands, published salinity indices, vegetation indices, and texture information. Additionally, multi-sensor data of Sentinel from dry and wet seasons were used to determine the best solution for mapping saline cropland. The results imply that combining the Sentinel-1 and Sentinel-2 data could map the soil salinity in HID during the dry season with reasonable accuracy and close to real time. Then, the indicators derived from the confusion matrix were used to validate the established model. As a result, the combined dataset, which included reflectance bands, spectral indices, vertical transmit–vertical receive (VV) and vertical transmit–horizontal receive (VH) polarization, and texture information, outperformed the highest overall accuracy at 0.8938, while the F1 scores for saline cropland and non-saline cropland are 0.8687 and 0.9109, respectively. According to the analyses conducted for this study, salt-affected cropland can be detected more accurately during the dry season by using just Sentinel images from March to April. The findings of this study provide a clear explanation of the efficiency and standardization of salt-affected cropland mapping in arid and semi-arid regions, with significant potential for applicability outside the current study area

Clinical Trial Research on Mongolian Medical Warm Acupuncture in Treating Insomnia

Objective. Insomnia is one of the most common sleep disorders. Hypnotics have poor long-term efficacy. Mongolian medical warm acupuncture has significant efficacy in treating insomnia. The paper evaluates the role of Mongolian medical warm acupuncture in treating insomnia by investigating the Mongolian medicine syndromes and conditions, Pittsburgh sleep quality index, and polysomnography indexes. Method. The patients were diagnosed in accordance with International Classification of Sleep Disorders (ICSD-2). The insomnia patients were divided into the acupuncture group (40 cases) and the estazolam group (40 cases). The patients underwent intervention of Mongolian medical warm acupuncture and estazolam. The indicators of the Mongolian medicine syndromes and conditions, Pittsburgh sleep quality index (PSQI), and polysomnography indexes (PSG) have been detected. Result. Based on the comparison of the Mongolian medicine syndrome scores between the warm acupuncture group and the drug treatment group, the result indicated P<0.01. The clinical efficacy result showed that the effective rate (85%) in the warm acupuncture group was higher than that (70%) in the drug group. The total scores of PSQI of both groups were approximated. The sleep quality indexes of both groups decreased significantly (P<0.05). The sleep quality index in the Mongolian medical warm acupuncture group decreased significantly (P<0.01) and was better than that in the estazolam group. The sleep efficiency and daytime functions of the patients in the Mongolian medical warm acupuncture group improved significantly (P<0.01). The sleep time was significantly extended (P<0.01) in the Mongolian medical warm acupuncture group following PSG intervention. The sleep time during NREM in the Mongolian warm acupuncture group increased significantly (P<0.01). The sleep time exhibited a decreasing trend during REM and it decreased significantly in the Mongolian warm acupuncture group (P<0.01). The percentage of sleep time in the total sleep time during NREM3+4 in the Mongolian medical warm acupuncture group increased significantly. Conclusion. Mongolian medical warm acupuncture is efficient and safe in treating insomnia. It is able to better improve the patients’ sleep time and daytime functions. It is better than that in the estazolam group following drug withdrawal in terms of improving the sleep time. It is more effective in helping the insomnia patients than hypnotics