3,667 research outputs found
An analysis of expertise in intelligence analysis to support the design of human-centered artificial intelligence
Intelligence analysis involves unpredictable processes and decision making about complex domains where analysts rely upon expertise. Artificial Intelligence (AI) systems could support analysts as they perform analysis tasks, to enhance their expertise. However, systems must also be cognisant about how expertise is gained and designed so that this is not impinged. In this paper, we describe the results of Cognitive Task Analysis interviews with 6 experienced intelligence analysts. We capture themes, in terms of their decision making paths during an analysis task, and highlight how each theme is both influenced by expertise and an influence upon expertise. We also identify important interdependencies between themes. We propose that our findings can be used to help design Human-Centered AI (HCAI) systems for supporting intelligence analysts
Stable Isotopic TracingāA Way Forward for Nanotechnology
Numerous publications and reports have expressed health and safety concerns about the production and use of nanoparticles, especially in areas of exposure monitoring, personal use, and environmental fate and transport. We suggest that stable isotopic tracers, which have been used widely in the earth sciences and in metabolic and other health-related studies for several decades, could be used to address many of these issues. One such example we are pursuing is the use of stable isotopes to monitor dermal absorption of zinc and titanium oxides in sunscreen preparations and other personal care products. Other potential applications of this tracing approach are discussed
Antihypertensive drug class and dyslipidemia: risk association among Chinese patients with uncomplicated hypertension
Factors associated with dyslipidemia in Chinese patients with uncomplicated hypertension were investigated in 1,139 patients newly prescribed a single antihypertensive drug in the public primary healthcare setting in Hong Kong, where their fasting lipid profiles were measured 4 to 16 weeks after the first prescription. Multivariate logistic regression showed that thiazide users were more likely (OR 3.67, 95% C.I. 1.13, 11.88, p=0.030) to have adverse (> 6.2mmol/l) total cholesterol (TC) compared with drugs acting on the renin angiotensin system (RAS), but the absolute difference in mean TC between thiazide users and all patients was small ( 0.14 mmol/l), while advanced age and male gender were also associated with some aspects of dyslipidemia. Clinicians should be aware of the increased risk of dyslipidemia in these groups, but the mild dyslipidemic profile associated with thiazides should not in itself deter its use as a possible first-line antihypertensive agent among Chinese patients
AtPAP2 modulates the import of the small subunit of Rubisco into chloroplasts
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Comparison of Small RNA Profiles of Glycine max and Glycine soja at Early Developmental Stages
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Rats distinguish between absence of events and lack of evidence in contingency learning.
The goal of three experiments was to study whether rats are aware of the difference between absence of events and lack of evidence. We used a Pavlovian extinction paradigm in which lights consistently signaling sucrose were suddenly paired with the absence of sucrose. The crucial manipulation involved the absent outcomes in the extinction phase. Whereas in the Cover conditions, access to the drinking receptacle was blocked by a metal plate, in the No Cover conditions, the drinking receptacle was accessible. The Test phase showed that in the Cover conditions, the measured expectancies of sucrose were clearly at a higher level than in the No Cover conditions. We compare two competing theories potentially explaining the findings. A cognitive theory interprets the observed effect as evidence that the rats were able to understand that the cover blocked informational access to the outcome information, and therefore the changed learning input did not necessarily signify a change of the underlying contingency in the world. An alternative associationist account, renewal theory, might instead explain the relative sparing of extinction in the Cover condition as a consequence of context change. We discuss the merits of both theories as accounts of our data and conclude that the cognitive explanation is in this case preferred
A novel oxygen carrier 'YQ23' suppresses the liver tumor metastasis by decreasing circulating endothelial progenitor cells and regulatory T cells
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