Incorporating project uncertainty in novel environmental biotechnologies: illustrated using phytoremediation

"Pollution of the environment by metals and organic contaminants is an intractable global problem, with cleanup costs running into billions of dollars using current engineering technologies. The availability of alternative, cheap and effective technologies would significantly improve the prospects of cleaning-up metal contaminated sites. Phytoremediation has been proposed as an economical and ‘green' method of exploiting plants to extract or degrade the contaminants in the soil. To date, the majority of phytoremediation efforts have been directed at leaping the biological, biochemical and agronomic hurdles to deliver a working technology, with scant attention to the economic outlook other than simple estimates of the cost advantages of phytoremediation over other techniques. In this paper we use a deterministic actuarial model to show that uncertainty in project success (the possibility that full clean up may not be realized) may significantly increase the perceived costs of remediation works for decision-makers." Authors' Abstractbiotechnology, Soil contaminants, Environmental remediation Economic aspects, Industrial crop technologies,

Minimally invasive management of sleeve gastrectomy collection with a nasobiliary drainage tube

A staple line leak is a feared complication of sleeve gastrectomy. Endoscopic methods have superseded surgical management of small leaks, however large collections often require surgical intervention. Here, we describe endoscopic management of large collection adjacent to the staple line with an 8Fr nasobiliary tube

Exploring factors related to the translation of collaborative research learning experiences into clinical practice : opportunities and tensions

Providing training opportunities to develop research skills for clinical staff has been prioritised in response to the need for improving the evidence base underpinning the delivery of care. By exploring the experiences of a number of former participants of a multidisciplinary postgraduate research course, this article explores the factors that have enabled and impeded staff to translate their learnt research skills into clinical practice. Adopting an exploratory case study approach, 16 interviews with 5 cohorts of Masters by Research in Clinical Practice (MResCP) graduates were undertaken. The interviews explored graduates’ course experiences and their subsequent attempts to undertake clinical research. Analysis of the data indicated that although participants valued their interactions with colleagues from different professions and felt they gained useful research skills/knowledge, upon returning to clinical practice, they encountered a number of barriers which restricted their ability to apply their research expertise. Professional isolation, issues of hierarchy, and a lack of organisational support were key to limiting their ability to undertake clinical research. Further work is needed to explore in more depth how (i) these barriers can be overcome and (ii) how taught collaborative research skills can be more effectively translated into practice

Behavioral and morphological traits interact to promote the evolution of alternative reproductive tactics in a lizard

Alternative reproductive tactics (ARTs) are predicted to be the result of disruptive correlational selection on suites of morphological, physiological, and behavioral traits. ARTs are most obvious when they occur in discrete morphs with concomitant behav

Movement Patterns of Resident and Relocated Northern Bobwhites in East Texas

We compared home range sizes and movement patterns of resident and relocated northern bobwhites (Colinus virginianus) on an area managed specifically for the species in the Pineywoods of east Texas. During the winters of 1990–1992, 155 south Texas, 136 east Texas, and 139 resident bobwhites were radiomarked, released, and thereafter regularly located. Bird locations were plotted on a digitized map, and home range sizes and movement patterns of each group of birds were estimated. Resident bobwhites moved longer daily distances in March and had larger home ranges during the nesting season (May-Jul) than relocated birds (P \u3c= 0.05). Conversely, no differences were detected among groups in mean of daily distances moved in April or dispersal during the breeding season (Mar-Jun) (P 0.05). Annual dispersal distances (x¯ = 1.43 km) of birds that survived into November were similar among groups (P \u3e 0.05). Managers that elect to relocate northern bobwhites should consider doing so in the fall and only into habitats of ample size

Olfactory Acuity in Chronic Migraine: A Cross-Sectional Study.

OBJECTIVE/BACKGROUND: This study aims to measure olfactory acuity in chronic migraine subjects, at baseline and on migraine days, and compare to age- and sex-matched controls. Olfactory impairment is common in neurological disorders. While smell hypersensitivity has been established with chronic migraine, olfactory acuity has not been well studied. METHODS: We recruited 50 subjects with chronic migraine from the Jefferson Headache Center and 50 age- and sex-matched controls. Using the University of Pennsylvania Smell Identification Test (UPSIT), a validated test of olfaction, olfactory acuity was measured at baseline and during a migraine for subjects, and compared to controls at baseline and at home 2 weeks later. All subjects were additionally screened for odor sensitivity and allodynia. RESULTS: The mean UPSIT score for migraine subjects was 34.5 on non-migraine days and 34.7 on migraine days (mean difference = -0.4, 95% confidence interval [CI; -1.3, 0.6] P = .45). Controls had a mean of 35.9 and 36.1 for each test day (mean difference = -0.1, 95% CI [-0.9, 0.7] P = .87). On average, migraineurs performed worse than their matched control counterparts in both test sittings (test 1: P = .047; test 2: P = .01). The great majority of subjects were allodynic (42/50) compared with only 9 of 50 controls, and the majority of subjects (41/50) found more than one listed odor to be bothersome, compared with only 10/50 controls. On non-migraine days, 18/48 chronic migraine subjects had abnormal olfaction and on migraine days 14/42 had abnormal olfaction, compared with only 9/50 controls who had abnormal olfaction on their first UPSIT. CONCLUSIONS: While chronic migraine patients do not appear to have a significant change in olfactory acuity between migrainous and non-migrainous periods, they do appear to be more likely to have abnormal olfactory acuity at baseline compared to age- and sex-matched controls

Tethys and Annex IV Progress Report for FY 2012

The marine and hydrokinetic (MHK) environmental Impacts Knowledge Management System, dubbed “Tethys” after the mythical Greek titaness of the seas, is being developed by the Pacific Northwest National Laboratory (PNNL) to support the U.S. Department of Energy’s Wind and Water Power Program (WWPP). Functioning as a smart database, Tethys enables its users to identify key words or terms to help gather, organize and make available information and data pertaining to the environmental effects of MHK and offshore wind (OSW) energy development. By providing and categorizing relevant publications within a simple and searchable database, Tethys acts as a dissemination channel for information and data which can be utilized by regulators, project developers and researchers to minimize the environmental risks associated with offshore renewable energy developments and attempt to streamline the permitting process. Tethys also houses a separate content-related Annex IV data base with identical functionality to the Tethys knowledge base. Annex IV is a collaborative project among member nations of the International Energy Agency (IEA) Ocean Energy Systems – Implementing Agreement (OES-IA) that examines the environmental effects of ocean energy devices and projects. The U.S. Department of Energy leads the Annex IV working with federal partners such as the Federal Energy Regulatory Commission (FERC), the Bureau of Ocean Energy Management (BOEM), and the National Oceanic Atmospheric Administration (NOAA). While the Annex IV database contains technical reports and journal articles, it is primarily focused on the collection of project site and research study metadata forms (completed by MHK researchers and developers around the world, and collected by PNNL) which provide information on environmental studies and the current progress of the various international MHK developments in the Annex IV member nations. The purpose of this report is to provide a summary of the content, accessibility and functionality enhancements made to the Annex IV and Tethys knowledge bases in FY12

Movement Patterns of Resident and Relocated Northern Bobwhites in East Texas

We compared home range sizes and movement patterns of resident and relocated northern bobwhites (Colinus virginianus) on an area managed specifically for the species in the Pineywoods of east Texas. During the winters of 1990–1992, 155 south Texas, 136 east Texas, and 139 resident bobwhites were radiomarked, released, and thereafter regularly located. Bird locations were plotted on a digitized map, and home range sizes and movement patterns of each group of birds were estimated. Resident bobwhites moved longer daily distances in March and had larger home ranges during the nesting season (May-Jul) than relocated birds (P0.05). Managers that elect to relocate northern bobwhites should consider doing so in the fall and only into habitats of ample size