51 research outputs found

    2005-2006 Nothing but Klezmer

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    Concert Dates: Thursday, November 17, 2005 at 7:30 pm Friday, November 18, 2005 at 7:30 pmhttps://spiral.lynn.edu/conservatory_otherseasonalconcerts/1040/thumbnail.jp

    2004-2005 Nothing but Klezmer: Swingin\u27 Jazz and Klezmer Band

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    Concert Dates: Wednesday, December 1, 2004 at 7:30 pm Thursday, December 2, 2004 at 7:30 pmhttps://spiral.lynn.edu/conservatory_otherseasonalconcerts/1051/thumbnail.jp

    2009-2010 Nothing but Klezmer

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    Concert Dates: Friday, March 19, 2010 at 7:30 pm Saturday, March 20, 2010 at 7:30 pmhttps://spiral.lynn.edu/conservatory_otherseasonalconcerts/1027/thumbnail.jp

    2008-2009 Nothing but Klezmer

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    Concert Dates: Friday, December 12, 2008 at 7:30 pm Saturday, December 13, 2008 at 4:00 pm Saturday, December 13, 2008 at 7:30 pmhttps://spiral.lynn.edu/conservatory_otherseasonalconcerts/1032/thumbnail.jp

    2007-2008 Nothing but Klezmer

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    Concert Dates: Friday, March 21, 2008 at 7:30 pm Saturday, March 22, 2008 at 7:30 pmhttps://spiral.lynn.edu/conservatory_otherseasonalconcerts/1034/thumbnail.jp

    2010-2010 Nothing but Klezmer

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    https://spiral.lynn.edu/conservatory_otherseasonalconcerts/1024/thumbnail.jp

    2011-2012 Nothing but Klezmer

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    https://spiral.lynn.edu/conservatory_otherseasonalconcerts/1023/thumbnail.jp

    Development of Twitching in Sleeping Infant Mice Depends on Sensory Experience

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    SummaryMyoclonic twitches are jerky movements that occur exclusively and abundantly during active (or REM) sleep in mammals, especially in early development [1–4]. In rat pups, limb twitches exhibit a complex spatiotemporal structure that changes across early development [5]. However, it is not known whether this developmental change is influenced by sensory experience, which is a prerequisite to the notion that sensory feedback from twitches not only activates sensorimotor circuits but modifies them [4]. Here, we investigated the contributions of proprioception to twitching in newborn ErbB2 conditional knockout mice that lack muscle spindles and grow up to exhibit dysfunctional proprioception [6–8]. High-speed videography of forelimb twitches unexpectedly revealed a category of reflex-like twitching—comprising an agonist twitch followed immediately by an antagonist twitch—that developed postnatally in wild-types/heterozygotes, but not in knockouts. Contrary to evidence from adults that spinal reflexes are inhibited during twitching [9–11], this finding suggests that twitches trigger the monosynaptic stretch reflex and, by doing so, contribute to its activity-dependent development [12–14]. Next, we assessed developmental changes in the frequency and organization (i.e., entropy) of more-complex, multi-joint patterns of twitching; again, wild-types/heterozygotes exhibited developmental changes in twitch patterning that were not seen in knockouts. Thus, targeted deletion of a peripheral sensor alters the normal development of local and global features of twitching, demonstrating that twitching is shaped by sensory experience. These results also highlight the potential use of twitching as a uniquely informative diagnostic tool for assessing the functional status of spinal and supraspinal circuits

    2003-2004 Third Annual Klezmer Concert

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    Concert Dates: December 5, 2003 at 7:30 pm December 6, 2003 at 7:30 pmhttps://spiral.lynn.edu/conservatory_otherseasonalconcerts/1060/thumbnail.jp
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