Design of a 2.4 GHz High-Performance Up-Conversion Mixer with Current Mirror Topology

In this paper, a low voltage low power up-conversion mixer, designed in a Chartered 0.18 μm RFCMOS technology, is proposed to realize the transmitter front-end in the frequency band of 2.4 GHz. The up-conversion mixer uses the current mirror topology and current-bleeding technique in both the driver and switching stages with a simple degeneration resistor. The proposed mixer converts an input of 100 MHz intermediate frequency (IF) signal to an output of 2.4 GHz radio frequency (RF) signal, with a local oscillator (LO) power of 2 dBm at 2.3 GHz. A comparison with conventional CMOS up-conversion mixer shows that this mixer has advantages of low voltage, low power consumption and high-performance. The post-layout simulation results demonstrate that at 2.4 GHz, the circuit has a conversion gain of 7.1 dB, an input-referred third-order intercept point (IIP3) of 7.3 dBm and a noise figure of 11.9 dB, while drawing only 3.8 mA for the mixer core under a supply voltage of 1.2 V. The chip area including testing pads is only 0.62×0.65 mm2

The protective role of pregnane X receptor in lipopolysaccharide/D-galactosamine-induced acute liver injury.

The pregnane X receptor (PXR) is a nuclear receptor transcription factor regulating drug-metabolizing enzymes and transporters that facilitate xenobiotic and endobiotic detoxification. Recent studies show that PXR is important in abrogating intestinal tissue damage. This study examines the role of PXR in lipopolysaccharide (LPS)/D-galactosamine (GalN)-induced acute liver injury using wild-type and PXR-null mice. LPS/GalN-treated PXR-null mice had greater increases of alanine transaminase (ALT), hepatocyte apoptosis, necrosis, and hemorrhagic liver injury than wild-type mice. LPS/GalN-mediated phosphorylation of JNK1/2 and ERK1/2 was differentially regulated in wild-type and PXR-null mice. Importantly, LPS/GalN-induced hepatic Stat3 survival signaling was impaired and early activation of Jak2 was delayed in PXR-null mice. Expression levels of pro-survival proteins Bcl-xL and heme oxygenase-1 (HO-1), which are downstream of Stat3, were substantially lower in PXR-null than wild-type mouse livers after LPS/GalN treatment. Autophagy is also involved in LPS/GalN-induced liver injury. Lack of PXR resulted in a significant reduction of LC3B-I, -II as well as Beclin-1 protein levels after LPS/GalN treatment. In addition, PXR is implicated in hepatocytes homeostasis. Taken together, PXR is a critical hepatoprotective factor. Increases of LPS/GalN-induced hepatocyte apoptosis and liver injury in PXR-null mice are due to deregulated mitogen-activated protein (MAP) kinase activation as well as delayed Jak2/Stat3 activation, which lead to a compromise in defense mechanisms that involve Bcl-xL-, HO-1, and autophagy-mediated pathways

Electron transport through Al-ZnO-Al: an {\it ab initio} calculation

The electron transport properties of ZnO nano-wires coupled by two aluminium electrodes were studied by {\it ab initio} method based on non-equilibrium Green's function approach and density functional theory. A clearly rectifying current-voltage characteristics was observed. It was found that the contact interfaces between Al-O and Al-Zn play important roles in the charge transport at low bias voltage and give very asymmetric I-V characteristics. When the bias voltage increases, the negative differential resistance occurs at negative bias voltage. The charge accumulation was calculated and its behavior was found to be well correlated with the I-V characteristics. We have also calculated the electrochemical capacitance which exhibits three plateaus at different bias voltages which may have potential device application.Comment: 10 pages, 6 figure

Shot noise of spin current and spin transfer torque

We report the theoretical investigation of noise spectrum of spin current and spin transfer torque for non-colinear spin polarized transport in a spin-valve device which consists of normal scattering region connected by two ferromagnetic electrodes. Our theory was developed using non-equilibrium Green's function method and general non-linear $S^\sigma-V$ and $S^\tau-V$ relations were derived as a function of angle $\theta$ between magnetization of two leads. We have applied our theory to a quantum dot system with a resonant level coupled with two ferromagnetic electrodes. It was found that for the MNM system, the auto-correlation of spin current is enough to characterize the fluctuation of spin current. For a system with three ferromagnetic layers, however, both auto-correlation and cross-correlation of spin current are needed to characterize the noise spectrum of spin current. Furthermore, the spin transfer torque and the torque noise were studied for the MNM system. For a quantum dot with a resonant level, the derivative of spin torque with respect to bias voltage is proportional to $\sin\theta$ when the system is far away from the resonance. When the system is near the resonance, the spin transfer torque becomes non-sinusoidal function of $\theta$. The derivative of noise spectrum of spin transfer torque with respect to the bias voltage $N_\tau$ behaves differently when the system is near or far away from the resonance. Specifically, the differential shot noise of spin transfer torque $N_\tau$ is a concave function of $\theta$ near the resonance while it becomes convex function of $\theta$ far away from resonance. For certain bias voltages, the period $N_\tau(\theta)$ becomes $\pi$ instead of $2\pi$. For small $\theta$, it was found that the differential shot noise of spin transfer torque is very sensitive to the bias voltage and the other system parameters.Comment: 15pages, 6figure

The Design and Application of Automatic Control System for Inorganic Membrane Filter

AbstractFor the existing inorganic membrane filter, this paper set up an automatic control system using PLC and touching screen, unified regenerate counter blowing control, online discharging control, pneumatic conveying control, process monitoring display and alarm etc., to reach the remote and on-site control. Hardware composing and software function of control system has been built. Performance parameters, match with actual capacity, of dust removal system are set by application. The application indicates that: when the pressure drop set to 25000 pa, regeneration counter blowing program starts, counter blowing interval set to 15s, counter blowing time set to 0.15s, pulse cleaning pressure set to 6860000 pa, the whole system moves stably and reliably, and it has high efficiency of dust removal