421 research outputs found
Is the electroencephalogram with brain mapping superior to the traditional electroencephalogram for the diagnosis of neurological pathologies?
Desigualdade de renda e informalidade do trabalho: uma análise RIF para o Brasil de 2012 a 2019
Este trabalho investiga a dinâmica da desigualdade de renda no mercado de trabalho brasileiro no perÃodo de 2012 a 2019, dando um enfoque particular à contribuição da informalidade do trabalho nas trajetórias de queda e, sobretudo, elevação da disparidade ocorridas ao longo deste intervalo. Para tanto, utiliza-se uma estratégia de decomposição baseada em regressões RIF, a partir da qual torna-se possÃvel a análise da contribuição de diversas covariadas sobre mudanças de Ãndices de desigualdade. Os resultados sugerem que a dinâmica equalizadora da distribuição de renda entre 2012 e 2015 e con- duzida por efeitos prêmios setoriais, os quais conseguem compensar mudanças composicionais concentradoras. Alternativamente, o perÃodo seguinte de 2015 a 2019 tem sua ascensão da desigualdade de renda liderada por efeitos composição relativos ao aumento da informalidade do trabalho e, principalmente, à expansão da escolaridade neste perÃodo, tendo em vista o papel dispersivo da existência de retornos convexos à educação. A análise relativa à s caudas inferior e superior da distribuição sugere que a queda da desigualdade ocorrida em ambas no primeiro perÃodo e liderada por efeitos macroeconômicos não observáveis. Por outro lado, ao passo que a cauda superior tem seu movimento concentrador expresso em termos de mudanças composicionais relativos à expansão da escolaridade entre 2015 e 2019, a cauda inferior tem na elevação da informalidade do trabalho o componente explicativo mais importante para a alta da disparidade ocorrida neste perÃodo
Tratamento do cisto pilonidal: cicatrização por segunda intenção ou sutura primária em linha média?
Efficacy and safety in the use of intraperitoneal hyperthermia chemotherapy and peritoneal cytoreductive surgery for pseudomyxoma peritonei from appendiceal neoplasm: A systematic review
The objective of this systematic review is to provide efficacy and safety data in the application of Intra-Abdominal Hyperthermia Chemotherapy (HIPEC) and Cytoreductive Surgery (CRS) in patients with Peritoneal Pseudomyxoma (PMP) of origin in the cecal appendix. The databases Medline and Central Cochrane were consulted. Patients with PMP of origin in the cecal appendix, classified as low grade, high or indeterminate, submitted to HIPEC and CRS. The results were meta-analyzed using the Comprehensive Metanalysis software. Twenty-six studies were selected to support this review. For low-grade PMP outcome, 60-month risk of mortality, Disease-Free Survival (DFS), and adverse events was 28.8% (95% CI 25.9 to 32), 43% (95% CI 36.4 and 49.8), and 46.7% (95% CI 40.7 to 52.8); for high-grade PMP, 60-month risk of mortality, Disease-Free Survival (DFS) and adverse events was 55.9% (95% CI 51.9 to 59.6), 20.1% (95% CI 15.5 to 25.7) and 30% (95% CI 25.2 to 35.3); PMP indeterminate degree, 60-month risk of mortality, Disease-Free Survival (DFS) and adverse events was 32.6% (95% CI 30.5 to 34.7), 61.8% (95% CI 58.8 to 64.7) and 32.9% (95% CI 30.5 to 35.4). The authors conclude that the HIPEC technique and cytoreductive surgery can be applied to selected cases of patients with PMP of peritoneal origin with satisfactory results
Incontinência urinária masculina: EsfÃncter artificial
The Guidelines Project, an initiative of the Brazilian Medical Association, aims to combine information from the medical field in order to standardize procedures to assist the reasoning and decision-making of doctors. The information provided through this project must be assessed and criticized by the physician responsible for the conduct that will be adopted, depending on the conditions and the clinical status of each patient.Univ Fed São Paulo, Soce Brasileira Urol, São Paulo, BrazilAC Camargo Canc Ctr, Soc Brasileira Urol, São Paulo, BrazilSoc Brasileira Urol, Rio De Janeiro, BrazilAMB, São Paulo, BrazilUniv Fed São Paulo, Soce Brasileira Urol, São Paulo, BrazilWeb of Scienc
Mepolizumab in Hypereosinophilic Syndrome: A Systematic Review and Meta-analysis
We aimed to evaluate the efficacy and safety of mepolizumab (MEP) in the management of hypereosinophilic syndrome (HES). A systematic search was performed, and articles published until March 2021 were analyzed. The primary efficacy results evaluated were hospitalization rate related to HES, morbidity (new or worsening), relapses/failure, treatment-related adverse effects, prednisone dosage ≤10 mg/day for ≥8 weeks, and eosinophil count <600/μL for ≥8 weeks. A meta-analysis was conducted, when appropriate. Three randomized controlled trials (RCTs), with a total of 255 patients, were included. The studies contemplated the use of MEP 300 mg/SC or 750 mg/IV. According to the evaluation of the proposed outcomes, when relapse rates/therapeutic failures were assessed, there was a 26% reduction with MEP 300 mg/SC (RD=-0.26; 95% CI: -0.44 to -0.08; p=0.04) and 48% reduction with MEP 750 mg/IV (RD=-0.48; 95% CI: -0.67, -0.30; p<0.00001). For the outcomes, prednisone dosage ≤10 mg/day for ≥8 weeks was 48% (RD=0.48; 95% CI: 0.35 to 0.62; p<0.00001), and the eosinophil count <600/μL for ≥8 weeks was 51% (RD=0.51; 95% CI: 0.38 to 0.63; p<0.00001), both showed a reduction with MEP 300 mg/IV and 750 mg/IV. No statistically significant differences in treatment-related adverse effects outcomes were observed for either dosage (RD=0.09; 95% CI: -0.05 to 0.24; p=0.20; RD=0.09; 95% CI: -0.11 to 0.29; p=0.39). Despite the positive effects observed for the studied outcomes, the exact significance remains unclear
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