401 research outputs found

    Western and Central Asia. Satellite Imagery for the Study of Conservation and Restoration of Earthen Architecture. Research carried out between July and September 2022

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    Conservation and restoration of archaeological earthen architecture in the countries of Western and Central Asia is critical but challenging due to the tendency of earthen architecture to deteriorate once exposed to weathering and other decay agents. The paper presents a comparative analysis of the practices carried out in the area, with the use of satellite environmental and climatic data about rainfall, snow-ice cover, and average land surface temperature data for day and night. The aim is to propose an approach that gives the opportunity to compare the different practices employed and their effectiveness on the basis of various climatic and environmental elements.Conservation and restoration of archaeological earthen architecture in the countries of Western and Central Asia is critical but challenging due to the tendency of earthen architecture to deteriorate once exposed to weathering and other decay agents. The paper presents a comparative analysis of the practices carried out in the area, with the use of satellite environmental and climatic data about rainfall, snow-ice cover, and average land surface temperature data for day and night. The aim is to propose an approach that gives the opportunity to compare the different practices employed and their effectiveness on the basis of various climatic and environmental elements

    Identification and characterization of cytogenetic profile in olfactory neuroblastoma by array comparative genomic hybridization

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    Aim: the Olfactory Neuroblastoma (ONB) is an uncommon malignant tumor arising from the olfactory epithelium. Due to its rarity, the molecular and cytogenetic profiles are not well-known. The aim of the study is to better define the cytogenetic profile of ONB analyzed by Comparative Genomic Hybridization on Microarray (a-CGH) and identify possible correlations with clinical and pathological features. Materials and methods: 13 patients affected with ONB were collected and treated at Ospedale di Circolo of Varese, University of Insubria. At the Section of Biology and Medical Genetic, the DNA was extracted and isolated. We asseyed 14 samples using a-CGH technique: ten primary tumors, two relapsed tumors and two samples were from the same patient at onset and at relapse. Results: our results on chromosome imbalances highlight the highly heterogeneous presentation: seven of 13 samples showed multiple numerical changes and very few structural ones, while four samples showed an opposite pattern; one samples showed no imbalances. We did not reach firm evidence of any recurrent specific imbalances either at level of entire chromosomes or chromosome segments. Conclusion: Gain of chromosome 19 is the only corrispondence with literature data concerning an entire chromosome and most segmental gains and losses found in our cohort of patients are different from those indicated in the literature: the only similarities are the gain of 20q13 and the loss of segments of chromosome 15 and 22

    Simulated synchrotron and Inverse Compton emission from Pulsar Wind Nebulae

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    We present a complete set of diagnostic tools aimed at reproducing synthetic non-thermal (synchrotron and/or Inverse Compton, IC) emissivity, integrated flux energy, polarization and spectral index simulated maps in comparison to observations. The time dependent relativistic magnetohydrodynamic (RMHD) equations are solved with a shock capturing code together with the evolution of the maximum particles energy. Applications to Pulsar Wind Nebulae (PWNe) are shown.Comment: 3 pages, 7 figures, proceeding of the conference "40 Years of Pulsars ", 12-17 August 2007, Montreal, Canada, submitted to AI

    Microwave-Assisted Synthesis, Optical and Theoretical Characterization of Novel 2-(imidazo[1,5-a]pyridine-1-yl)pyridinium Salts

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    In the last few years, imidazo[1,5-a]pyridine scaffolds and derivatives have attracted growing attention due to their unique chemical structure and optical behaviors. In this work, a series of pyridylimidazo[1,5-a]pyridine derivatives and their corresponding pyridinium salts were synthesized and their optical properties investigated to evaluate the effect of the quaternization on the optical features both in solution and polymeric matrix. A critical analysis based on the spectroscopic data, chemical structures along with density functional theory calculation is reported to address the best strategies to prevent aggregation and optimize the photophysical properties. The obtained results describe the relationship between chemical structure and optical behaviors, highlighting the role of pendant pyridine. Finally, the presence of a positive charge is fundamental to avoid any possible aggregation process in polymeric films

    Retroperitoneal and Retrograde Total Laparoscopic Hysterectomy – Technique with Three- and Five-millimeter Trocars

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    In this chapter, we describe total laparoscopic hysterectomy (TLH) using retroperitoneal and retrograde technique: it combines the retroperitoneal coagulation of the uterine artery and the retrograde approach to the pelvic organs, as in oncological surgeries. We report our experience in applying this modified TLH with 3-mm instruments and without uterine manipulator, in order to demonstrate its safety and feasibility

    Palatovaginal (pharyngeal) artery: clinical implication and surgical experience

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    The palatovaginal or pharyngeal artery is a small branch of the internal maxillary artery supplying the nasopharynx. Bleeding from this artery is exceptional and only one case of traumatic epistaxis from this artery has been reported previously. We report a case of a 66-year-old male presenting with right recurrent posterior epistaxis. Endoscopic dissection of the pterygopalatine fossa and direct visualization of the palatosphenoidal canal permitted to identify the origin of bleeding, and coagulation of the pharyngeal artery solved the epistaxis. Although rare, intractable posterior epistaxis may arise from the pharyngeal artery. The anatomical knowledge of this artery and of the palatosphenoidal canal is of outmost importance in endoscopic transpterygoid and nasopharyngeal procedures, to identify the vidian canal, evaluate nasopharyngeal cancer spread in the pterygopalatine fossa, reduce bleeding during surgery of the nasopharynx, and harvest adequately the pedicle of the nasoseptal flap

    Universal testing for COVID-19 in patients undergoing cancer treatment during the second outbreak in Brescia

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    Background: The impact of coronavirus disease 2019 (COVID-19) has been overwhelming on patients with cancer, who may be at higher risk of developing severe disease. During the second COVID-19 outbreak in Italy, we planned universal microbiologic screening for patients scheduled for antineoplastic treatment. Methods: All patients with planned active treatment at Brescia University Radiation Oncology Department were screened for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA with repeated nasopharyngeal swabs (NPS) from October 31, 2020. Treatment continuation, suspension, or delay was modulated for patients testing positive according to clinical presentation. Results: From October 31, 2020, to February 6, 2021, 636 patients were enrolled and 1243 NPS were performed, of which 28 (2.25%) were positive. The infection rate was 2.52%; 81.3% of the patients with a positive NPS were asymptomatic, 2 had mild disease, and 1 severe disease that led to death. All patients already on treatment with mild or asymptomatic COVID-19 carried on the therapy with no or minimal delay. Median delay for patients with infection detected before treatment start was 16.5 days. Conclusions: Detected incidence of COVID-19 was lower during the second outbreak in our patients (2.52% vs 3.23%), despite the extensive testing schedule, and substantiates the high rate of asymptomatic infections and the low mortality among patients with COVID-19 (6.3% vs 38.5% during the first outbreak). Universal SARS-CoV-2 screening for all patients with planned treatment might allow early identification of patients with COVID-19, resulting in timely management that could improve clinical outcomes and prevent spread of the infection
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