60 research outputs found
Quality of Life as Defined by Chinese Americans with Disabilities: Implications for Rehabilitation Services
We hypothesized that Chinese Americans with disabilities may remain culturally attached to their ancestors\u27 homeland and this cultural attachment may have influences on the concept of Quality of Life (QOL). That is, QOL may be perceived, by Chinese Americans with disabilities, not only as an individual\u27s satisfaction with his or her life, but also the person\u27s fulfillment of his or her responsibilities to his or her family and community. Of course, this hypothesis needs to be examined. Such an investigation may provide rehabilitation counselors with insights into the meaning of QOL from the viewpoint of Chinese Americans with disabilities. It may also point out the directions of how to improve rehabiUtation services to this population based on an understanding of the Chinese culture and its influences on rehabilitation goal-setting of Chinese Americans with disabilities. Accordingly, the purposes of this study were (a) to identify dimensions of QOL perceived by Chinese Americans/immigrants with disabilities and (b) to explore the presumable influence of cultural factors in the QOL of these individuals
Updating the Secondary Transition Research Base: Evidence- and Research-Based Practices in Functional Skills
Transition education should be grounded in quality research. To do so, educators need information on which practices are effective for teaching students with disabilities transition-related skills. The purpose of this systematic literature review was to identify evidence-based and research-based practices in secondary special education and transition for students with disabilities. This systematic review resulted in the identification of nine secondary transition evidence-based practices and 22 research-based practices across more than 45 different transition-related skills. The range of effects for each of the secondary transition evidence-based and research-based practices identified are also included. Limitations and implications for future research, policy, and practice are discussed
Updating the Secondary Transition Research Base: Evidence - and Research - Based Practices in Functional Skills
Transition education should be grounded in quality research. To do so, educators need information on which practices are effective for teaching students with disabilities transition-related skills. The purpose of this systematic literature review was to identify evidence-based and research-based practices in secondary special education and transition for students with disabilities. This systematic review resulted in the identification of nine secondary transition evidence-based practices and 22 research-based practices across more than 45 different transition-related skills. The range of effects for each of the secondary transition evidence-based and research-based practices identified are also included. Limitations and implications for future research, policy, and practice are discussed
Genotype-Phenotype Correlation in NF1: Evidence for a More Severe Phenotype Associated with Missense Mutations Affecting NF1 Codons 844â848
Neurofibromatosis type 1 (NF1), a common genetic disorder with a birth incidence of 1:2,000â3,000, is characterized by a highly variable clinical presentation. To date, only two clinically relevant intragenic genotype-phenotype correlations have been reported for NF1 missense mutations affecting p.Arg1809 and a single amino acid deletion p.Met922del. Both variants predispose to a distinct mild NF1 phenotype with neither externally visible cutaneous/plexiform neurofibromas nor other tumors. Here, we report 162 individuals (129 unrelated probands and 33 affected relatives) heterozygous for a constitutional missense mutation affecting one of five neighboring NF1 codonsâLeu844, Cys845, Ala846, Leu847, and Gly848âlocated in the cysteine-serine-rich domain (CSRD). Collectively, these recurrent missense mutations affect âŒ0.8% of unrelated NF1 mutation-positive probands in the University of Alabama at Birmingham (UAB) cohort. Major superficial plexiform neurofibromas and symptomatic spinal neurofibromas were more prevalent in these individuals compared with classic NF1-affected cohorts (both p < 0.0001). Nearly half of the individuals had symptomatic or asymptomatic optic pathway gliomas and/or skeletal abnormalities. Additionally, variants in this region seem to confer a high predisposition to develop malignancies compared with the general NF1-affected population (p = 0.0061). Our results demonstrate that these NF1 missense mutations, although located outside the GAP-related domain, may be an important risk factor for a severe presentation. A genotype-phenotype correlation at the NF1 region 844â848 exists and will be valuable in the management and genetic counseling of a significant number of individuals
Home-based functional walking program for advanced cancer patients receiving palliative care: a case series
Provision and use of green space in Hong Kong's new towns: a socio-spatial analysis
published_or_final_versionUrban DesignMasterMaster of Urban Desig
âWhy Me?â: Characterological Self-Blame and Continued Victimization in the First Year of Middle School
Objective: This study examines the role of characterological self-blame as a unique risk factor associated with other known risk factors (depression and its behavioral and social correlates) for continued victimization across the first year of middle school. Method: Relying on a large, ethnically diverse sample of 1698 young adolescents (Mage=11.57, SD=.39; 55% female), self-report assessments in the fall and spring included perceptions of victim status, depressive symptoms, friendships, aggression, and responses to a hypothetical victimization vignette assessing both appraisals (characterological self-blame) and behavioral reactions (helpless responding). Results: In addition to depression, characterological self-blame emerged as the most consistent unique risk factor for subsequent victimization. Mediation analysis suggested that the continuity of victimization between fall and spring could be partially explained by increases in characterological self-blame and depressive symptoms. Additionally, cross-lagged panel analyses indicated reciprocal relations between peer victimization and characterological self-blame, suggesting cyclical processes. Conclusions: The study findings suggest that attribution-retraining in the beginning of middle school might help prevent escalating risk for continued peer victimization
Archean basement components and metamorphic overprints of the Rangnim Massif in the northern part of the Korean Peninsula and tectonic implications for the Sino-Korean Craton
The geology of the Korean Peninsulaâs northern part is little known to the international community. Even though
this area is a critical link between various eastern Asia terranes, its tectonic architecture and geochronological
framework are still gaps in knowledge. This study reports integrated field, geochemical and geochronological
characteristics of the Precambrian gneissic rocks from this region, focusing on the Rangnim Massif. The studied
samples are divisible into three groups according to their field occurrence as granitic gneiss, fine-grained biotite
gneiss and leuco-veins. The essential mineralogy of all these rocks is biotite (Bt), muscovite (Mu), plagioclase
(Pl), K-feldspar (Kf) and quartz. The analyzed samples show high SiO2 (65.92â77.63 wt%) and Al2O3 (10.23 to
17.56 wt%) contents, low MgO and CaO. Their K2O contents is mostly higher than Na2O. SIMS (Secondary Ion
Mass Spectrometry) zircon U-Pb dating of the eleven samples yields magmatic protolith ages of 2454â2567 Ma
and multiple metamorphic overprintings during the earliest Paleoproterozoic (~2.45 Ga), Paleoproterozoic
(1.87â1.93 Ga) and Jurassic (160 Ma). The presence of these potassic granitoids in different locations indicate
the high extent maturation of Neoarchean continental crust in the Rangnim Massif. Zircon Lu-Hf isotopic results
of these samples show large variations, mostly plotting between the Depleted mantle linear model line and
Chondritic Uniform Reservoir (CHUR) line, but some have negative ΔHf(t) values. Considering that their protoliths are all crust melting products, it can be concluded that the Neoarchean magmatism incorporated both
juvenile crustal components as well as a reworking of older crust. This is supported by the detection of rare early
Archean xenocrysts. Based on Juvenile crust having ΔHf values of ~0 before 3500â3600 Ma, it is concluded that
the reworked components were Eoarchean in age, not Hadean. Magmatic as well as Precambrian metamorphic
pulses of the Rangnim Massif show broad similarities with the eastern North China Craton, Gyeonggi and
Yeongnam Massifs and southwest Japan, which seem to suggest that they might share a coherent Precambrian
basement and evolutionary history, at least before the end of late Paleoproterozoic.This work
was funded by the research programs (Grant Nos. 41890834, 41890832,
41872197 and 41530208) supported by the National Nature Science
Foundation of China, CAS priority strategic program (XDB18030205), and
a research program (Grant No. 2017K1A1A2013180) supported by
National Research Foundation of South Korea
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