Mobile Test Viewer: Web Application for Interactive Exploration of Product Test Plans

Testing is an important part of the manufacturing process and in order to make sure proper test coverage exists, a test plan model is created in a database and used by production testers to execute tests on the plant floor. The need exists for a fast and simple way to view and modify these test plans that will complement the existing tools used for creating and executing tests. The solution offered here is to develop a mobile first web application that can present the test plan in a user friendly way and allow editing of test parameters as required. This results is an application that can be used on any device with a browser and does not require any special software or other dependencies. This application provides a resource for management and non-technical users to visualize a test plan as well as giving technical users the ability to troubleshoot and modify test plans on the manufacturing floor without the use of large desktop applications

Calorie restriction and resveratrol in cardiovascular health and disease

AbstractCalorie restriction is one of the most effective nutritional interventions that reproducibly protects against obesity, diabetes and cardiovascular disease. Recent evidence suggests that even when implemented over a short period, calorie restriction is a safe and effective treatment for cardiovascular disease. Herein, we review the effects of calorie restriction on the cardiovascular system as well as the biological effects of resveratrol, the most widely studied molecule that appears to mimic calorie restriction. An overview of microarray data reveals that the myocardial transcriptional effects of calorie restriction overlap with the transcriptional responses to resveratrol treatment. In addition, calorie restriction and resveratrol modulate similar pathways to improve mitochondrial function, reduce oxidative stress and increase nitric oxide production that are involved in atherosclerosis prevention, blood pressure reduction, attenuation of left-ventricular hypertrophy, resistance to myocardial ischemic injury and heart failure prevention. We also review the data that suggest that the effects of calorie restriction and resveratrol on the cardiovascular system may involve signaling through the silent information regulator of transcription (SIRT), Akt and the AMP-activated protein kinase (AMPK) pathways. While accumulating data demonstrate the health benefits of calorie restriction and resveratrol in experimental animal models, whether these interventions translate to patients with cardiovascular disease remains to be determined

Basin Wildrye (\u3cem\u3eLeymus cinereus\u3c/em\u3e) Pooled Tetraploid Accessions for U.S. Intermountain West Rangeland Reclamation

Basin wildrye (Leymus cinereus [Scribn. & Merr.] Á. Löve) is an important perennial, hardy, long-lived, cool season C3 native grass of rangeland plant communities throughout much of western United States and Canada. All classes of livestock and wildlife, including large and small birds and mammals, utilise the grass year round for food and protection due to its 2-3 m tall, stiff stature which provides standing winter cover. Though occurring in precipitation areas of 150-500 mm and elevations of 600 to 3,000 m, it is usually found in deep, well-drained soils of high water holding capacity along drainage areas. Seedling vigour is only fair, and stands may take 2 to 5 years to fully establish. While tolerant of low to moderate levels (\u3c 10 mmhos/cm3) of saline and sodic soils and short-term winter or spring flooding, it does not tolerate extended periods of inundation (Ogle et al. 2012). It also does not tolerate heavy grazing or haying in the spring and summer due to its high growing point and minimal regrowth capability, and misuse has caused diminished population density through much of its original range (Anonymous, Utah Farmer-Stockman 1983). In response to losses of basin wildrye, due to wildfires and invasive species as well as historical overgrazing, it is desired to bolster the populations of basin wildrye in the Great Basin and other parts of the U.S. Intermountain area. However, the only seed supplies with reasonable commercial availability have been sourced from sites distant to this geographic area and establishment and survival has been inconsistent. These include the varieties Magnar, an octoploid (2n=56) originally collected in south-eastern British Columbia (released 1979) and Trailhead, a tetraploid (2n=28) originally collected in south-central Montana (re-leased 1991). Washoe germplasm (2002; tetraploid) was released for use on harsh mining sites in Montana, and the variety Continental (2009) an octoploid developed from the hybridisation of Magnar and Trailhead (Ogle et al. 2012)

Flow Dynamics And Plasma Heating Of Spheromaks In SSX

We report several new experimental results related to flow dynamics and heating from single dipole-trapped spheromaks and spheromak merging studies at SSX. Single spheromaks (stabilized with a pair of external coils, see Brown, Phys. Plasmas 13 102503 (2006)) and merged FRC-like configurations (see Brown, Phys. Plasmas 13, 056503 (2006)) are trapped in our prolate (R = 0.2 m, L = 0.6 m) copper flux conserver. Local spheromak flow is studied with two Mach probes (r(1) = rho(i) ) calibrated by time-of-flight with a fast set of magnetic probes at the edge of the device. Both Mach probes feature six ion collectors housed in a boron nitride sheath. The larger Mach probe will ultimately be used in the MST reversed field pinch. Line averaged flow is measured by ion Doppler spectroscopy (IDS) at the midplane. The SSX IDS instrument measures with 1 mu s or better time resolution the width and Doppler shift of the C-III impurity (H plasma) 229.7 nm line to determine the temperature and line-averaged flow velocity (see Cothran, RSI 77, 063504 (2006)). We find axial flows up to 100 km/s during formation of the dipole trapped spheromak. Flow returns at the wall to form a large vortex. Recent high-resolution IDS velocity measurements during spheromak merging show bi-directional outflow jets at +/- 40 km/s (nearly the Alfven speed). We also measure T-i \u3e= 80 eV and T-e \u3e= 20 eV during spheromak merging events after all plasma facing surfaces are cleaned with helium glow discharge conditioning. Transient electron heating is inferred from bursts on a four-channel soft x-ray array. The spheromaks are also characterized by a suite of magnetic probe arrays for magnetic structure B(r,t), and interferometry for n(e) . Finally, we are designing a new oblate, trapezoidal flux conserver for FRC studies. Equilibrium and dynamical simulations suggest that a tilt-stable, oblate FRC can be formed by spheromak merging in the new flux conserver

Utah’s Watershed Restoration Initiative: Restoring Watersheds at a Landscape Scale

Abstract: The Utah Watershed Restoration Initiative (WRI) is a partnership-based program, administered by the Utah Department of Natural Resources, which seeks to improve the functional capacity of high priority watersheds throughout the state. Since its inception in 2006, the WRI partnership has completed nearly 1,500 projects to restore and rehabilitate over 526,091 ha in Utah watersheds. The WRI program is unique to the west, in that it transcends jurisdictional boundaries, and local, state, and federal management authority to focus finite resources on completing high priority conservation projects. We surveyed selected WRI selected participants in 2015 to determine what factors they believed most contributed to the overall success of the program. Survey respondents attributed the success of the WRI program to: 1) engaged leadership at multiple levels, 2) a bottom-up hierarchy, 3) a history of collaboration, 4) practice partnerships, 5) a science-based approach, 6) operating at a meaningful spatial scale, 7) being solution minded, not problem focused, and 8) unselfish sharing of resources. In this paper we discuss these success factors and provide recommendations to those desiring to implement voluntary incentive-based landscape conservation strategies

Improvement of Long COVID symptoms over one year.

IMPORTANCE: Early and accurate diagnosis and treatment of Long COVID, clinically known as post-acute sequelae of COVID-19 (PASC), may mitigate progression to chronic diseases such as myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Our objective was to determine the utility of the DePaul Symptom Questionnaire (DSQ) to assess the frequency and severity of common symptoms of ME/CFS, to diagnose and monitor symptoms in patients with PASC. METHODS: This prospective, observational cohort study enrolled 185 people that included 34 patients with PASC that had positive COVID-19 test and persistent symptoms of \u3e3 months and 151 patients diagnosed with ME/CFS. PASC patients were followed over 1 year and responded to the DSQ at baseline and 12 months. ME/CFS patients responded to the DSQ at baseline and 1 year later. Changes in symptoms over time were analyzed using a fixed-effects model to compute difference-in-differences estimates between baseline and 1-year follow-up assessments. PARTICIPANTS: Patients were defined as having PASC if they had a previous positive COVID-19 test, were experiencing symptoms of fatigue, post-exertional malaise, or other unwellness for at least 3 months, were not hospitalized for COVID-19, had no documented major medical or psychiatric diseases prior to COVID-19, and had no other active and untreated disease processes that could explain their symptoms. PASC patients were recruited in 2021. ME/CFS patients were recruited in 2017. RESULTS: At baseline, patients with PASC had similar symptom severity and frequency as patients with ME/CFS and satisfied ME/CFS diagnostic criteria. ME/CFS patients experienced significantly more severe unrefreshing sleep and flu-like symptoms. Five symptoms improved significantly over the course of 1 year for PASC patients including fatigue, post-exertional malaise, brain fog, irritable bowel symptoms and feeling unsteady. In contrast, there were no significant symptom improvements for ME/CFS patients. CONCLUSION AND RELEVANCE: There were considerable similarities between patients with PASC and ME/CFS at baseline. However, symptoms improved for PASC patients over the course of a year but not for ME/CFS patients. PASC patients with significant symptom improvement no longer met ME/CFS clinical diagnostic criteria. These findings indicate that the DSQ can be used to reliably assess and monitor PASC symptoms

Te Pūnaha Ātea -1 (TPA-1), A Capability Development and Validation Mission From New Zealand

We report an overview of the Te Pūnaha Ātea -1 (TPA-1) 3U CubeSat and its payloads, which is manifested for an upcoming launch. Within the context of the New Zealand space sector, the mission is aimed at developing and validating capability in mission delivery and operations through in-house processes and infrastructure. The mission includes four payloads comprising: a deployable/stowable inspection boom, an integrated Raspberry Pi based Earth observation and deployables imager, thermal monitoring payload and miniaturised dragsail for end-of-life disposal. The first mission by Te Pūnaha Ātea - Space Institute represents an important step along the path to becoming the hub for future aerospace activities in New Zealand

Te Pūnaha Ātea -1 (TPA-1), a Capability Development and Validation Mission From New Zealand

Operation goals: Capturing identifiable imagery of NZ landmass. Upload and use of student and researcher image processing tools. Inspecting exposed surfaces and elements of the CubeSat. Demonstrating and monitoring the deployable structures. Monitoring the thermal profile inside the CubeSat. Demonstrating timely de-orbit at end of life. Mission objectives: Commissioning and demonstration of TPA-SI facilities. Establishment and validation of mission delivery processes. Outreach, education and training in mission delivery and operations. Generation of core mission documentation set. Flight heritage for in-house spacecraft platform avionics and structures

3D Reconnection And Flow Dynamics In The SSX Experiment

Several new experimental results are reported from plasma merging studies at the Swarthmore Spheromak Experiment (SSX) with relevance to collisionless three-dimensional magnetic reconnection in laboratory and space plasmas. First, recent high-resolution velocity measurements of impurity ions using ion Doppler spectroscopy (IDS) show bi-directional outflow jets at 40 km/s (nearly the Alfven speed). The SSX IDS instrument measures with 1 mu s or better time resolution the width and Doppler shift of the C-III impurity (H plasma) 229.7 nm line to determine the temperature and line-averaged flow velocity during spheromak merging events. High flow speeds are corroborated using an in situ Mach probe. Second, ion heating to nearly 10(6) K is observed after reconnection events in a low-density kinetic regime. Transient electron heating is inferred from bursts on a 4-channel soft x-ray array as well as vacuum ultraviolet spectroscopy. Third, the out-of-plane magnetic field and the in-plane Lorentz force in a reconnection volume both show a quadrupolar structure at the ion inertial scale (c/omega(pi)). Time resolved vector magnetic field measurements on a 3D lattice B(r, t)) enables this measurement. Earlier work at SSX has shown that fori-nation of three-dimensional structure at the ion inertial scale is temporally and spatially correlated with the observation of superthermal, super-Alfvenic ions accelerated along the X-line normal to the local 2D plane of reconnection. Each of these measurements will be related to and compared with similar observations in a solar or space context