Angiomyofibroblastoma: a very rare tumour of vulva

Angiomyofibroblastoma is a rare benign mesenchymal tumor of vulva. Patient had history of gradually increased mass over 6 years of duration. It was painless, fibro-cystic mass of 6.8×4.6×2.5 cm hanging over right side labia majora without any menstrual or coitus difficulty. Cosmetic and risk of malignancy were the main issues. After complete examination and investigations simple excision done. Histological examination revealed mass composed of numerous capillaries and some ectatic blood vessels embedded within the hyalinised matrix. No lipomatous component was found within the tumour. Nuclear atypism and pleomorphism were absent and mitotic figures were not detected. All these were suggestive of benign mesenchymal tumor, angiomyofibroblastoma

Role of ferric carboxymaltose in battle with anemia among north Indian pregnant women

Background: Anemia among pregnant women is a serious global health concern. Anemia is a major hematological, nutritional deficiency but still a manageable health problem among the pregnant women and very common in developing countries like India in under privileged population. Increased morbidity and mortality is seen in pregnant women and their foetuses suffering from anemia. Aim of this study was to study safety and efficacy of injection ferric carboxymaltose in pregnant women with iron deficiency anemia. Methods: This is a Prospective interventional comparative randomized study carried among antenatal women in the Department of Obstetrics and Gynaecology, S. N. Medical College, Agra from (May 2021-October 2022), comprised of 200 pregnant women divided into two groups. Group A-100 antenatal women were transfused with iron sucrose (IS), Group B-100 antenatal women were transfused with ferric carboxymaltose (FCM). Results: In FCM group after 3 weeks of post transfusion hemoglobin level was 10.5±0.44 and in iron sucrose group it was 9.9±0.59 (p=0.0001). 6 week post transfusion hemoglobin level in FCM group was 11.37±0.62 and in iron sucrose group it was 10.45±0.59 (p=0.0001). Average rise in hemoglobin in FCM group after 3 week post transfusion was 2.9±0.02 and after 6 week it was 3.77±0.16. In iron sucrose group at 3 week it was 2.1±0.06 and at 6 week it was 2.65±0.04. The average rise in hemoglobin level was greater among patients of FCM compared to Iron sucrose group. Conclusions: Ferric carboxymaltose was safe and more effective in treatment of iron deficiency anaemia in pregnant women as compared to iron sucrose with lesser side effect and better patient compliance

EFFECT OF ALOE VERA GEL ON RAT MYOCARDIAL CONTRACTILITY, CHRONOTROPY AND CORONARY FLOW IN ISOLATED HEART

Background: Aloe vera L. (Syn.: ALOE BARBADENSIS Miller; Hindi: Ghikanvar; AV) is a cactus-like perennial plant belonging to family Liliaceae, consists of high content of phenolic compounds, glycosides (aloins), 1,8-dihydroxyanthraquinone derivatives (aloe emodin), beta-1,4 acetylated mannan, mannose-phosphate and alprogen glucoprotein. Review revealed that leaf exudates and mucilaginous gel of Aloe possesses anti-inflammatory, antifungal, antibacterial, anticancer, antioxidant, cytoprotective, cardiac stimulatory and immuno modulatory activities. Therefore in present study we studied the effect of aloe vera gel on contractile and other property of rat myocardium using isolated heart model. Methods: A total of 24 male albino rats were divided into four groups, one control and three experimental of six animals each. Aloe vera extract an aqueous solution of aloe barbadensis was prepared by taking 10 gm of gel from the fresh leaf of aloe plant and dissolved in 100 ml of distilled water. The hearts were perfused with aqueous solutions of Aloe in doses of 100mg, 200mg, and 300mg/l of Kreb’s solutions. Observation and Results: Our results showed that there was no significant deference in baseline HR and force of contraction among control and experimental groups. aloe vera in dose of 200mg/l and 300mg/l of Kerb’s–Henseleits solution was intervened showed highly significant change in force of contraction and coronary flow as compared in control. Conclusion: Our study showed that aloe vera causes increase in myocardial force of contraction and coronary flow; therefore aloe vera may be cardio protective

Search for high mass resonances decaying into W+W−W^+W^- in the dileptonic final state with 138 fb−1\mathrm{ fb^{-1} } of proton-proton collisions at \mathrm{\sqrt{s} = 13 {\ensuremath{\,\mathrm{TeV}}}}

A search for high mass resonances decaying into a pair of W bosons is presented. The analysis is based on proton-proton collisions recorded by the CMS experiment at the CERN LHC for full Run $2$, corresponding to an integrated luminosity of 138 $\mathrm{ fb^{-1} }$ at a center-of-mass energy of 13 {\ensuremath{\,\mathrm{TeV}}}. The analysis considers the fully leptonic final state. New techniques are implemented in the analysis to improve the sensitivity of the search, especially in the very high mass range. The search is performed in a mass range from 115 {\ensuremath{\,\mathrm{GeV}}} to 5 {\ensuremath{\,\mathrm{TeV}}} and for various width hypotheses. The effects of background and signal interference are also considered. The results are presented as 95\% confidence level upper limits on the product of the cross section and branching ratio on the production of a high mass resonance, as well as exclusion limits are derived on various two-Higgs-doublet models (2HDM) and minimal supersymmetric standard model (MSSM) benchmark scenarios

Potential antifungal plants for controlling building fungi

374-387The synthetic fungicides such as Pentachlorophenol, Tributyltin oxide, Zinc carboxylate, etc. have been removed from markets due to their harmful effects on the environment, residue problem and carcinogenic nature. However, the fungicides derived from plant products are safer alternatives for fungi control because they are richest source of bioactive phytochemicals such as alkaloids, terpenoides, polyacetylenes, unsaturated isobutylamides and phenolics. Plant products, traditionally used as biocides in indigenous culture are being re-evaluated for safer means of fungi control as compared to the synthetic. The present paper is an attempt to summarize antifungal potency of various plants along with their part (s) used, type of extracts and test fungi. In view of antifungal properties of some of these plants against some fungi found on buildings, it is hoped that detailed studies may yield many more effective natural fungicides for controlling various types of building fungi. Some fungi found commonly on buildings have also been discussed in this paper for ready reference and further studies on their possible control by plant extracts

Association of Biosocial Profile and Work Performance of Accredited Social Health Activist in Jaipur District

Introduction: Accredited social health activist (ASHA) is the first port of call for any health-related demands of deprived sections of the population, especially women and children, who find it difficult to access health services. ASHA's work performance is different in different areas and there are many factors that could influence ASHA work performance i.e. age, education, marital status, religion, caste, socio-economic status, family structure etc. Objective of this study was to determine the association between biosocial profile of ASHA with their work performance with special emphasis on maternal and child health activity. Methodology: This observational study was done in Chaksu block of Jaipur district, Rajasthan. Primary and secondary data were collected through Anganwadi register, village health index register of ASHA, Mamta card and personal interview with ASHA. ASHA's work performance was assessed and scored. Results: Almost all ASHAs were moderate performer. Significant gap was seen in first and fourth antenatal care (ANC) visits. Age, education, and socioeconomic status had significant influence while caste, religion, marital status, husband education, and family structure had no significant effect on her work performance. Conclusion: None of the socioeconomic variables such as age, education, socioeconomic status, religion, caste, family size, family type, husband education, and husband occupation were significantly associated with their work performance. Periodic training and motivation may improve and update their knowledge and skills for efficient work performance

Role of Yoga practices on cognitive functions: A review

Yoga is the science of conditioning one's mind and body via the practise of shatkarma, asana, pranayama, mudra, and meditation. The aim of this review of literature is to give theoretical rationale for identifying (a) the specific attributes of yoga poses that have been used in yoga protocols of various studies but have not been explicitly explored, & (b) the minimum time necessary to keep a posture to bring about a corresponding change in performance among the aforementioned cognitive functions (s) In humans, The most prevalent and under-treated problems are cognitive decline & psychological health problems. Different studies have been carried out to determine the influence of Yoga on human cognitive and psychological health indices. However, no comprehensive examination of the effects of yoga-based therapy on human cognitive and mental health has been undertaken to far. Yoga is an ancient science that places a premium on disease prevention and treatment, as well as the percentage of health. Yoga is recognized to delay the effects of aging and has been found to be effective in the therapy of aging-related disorders. Yoga is a centuries-old discipline that is said to improve both physical and emotional well-being