257 research outputs found
Sekolah Dasar Inklusi untuk Anak Berkesulitan Belajar Spesifik (Abbs) di Kota Pontianak
Pendidikan merupakan salah satu faktor pendukung yang memegang peranan penting dalam seluruh sektor kehidupan, karena kualitas kehidupan suatu bangsa sangat erat dengan tingkat pendidikan. Anak berkebutuhan khusus juga perlu mendapat perhatian serius menyangkut keadaan tumbuh kembang dan kelanjutan pendidikannya. Salah satu kategori anak berkebutuhan khusus adalah anak berkesulitan belajar spesifik, yaitu yang secara nyata mengalami kesulitan dalam tugas akademik khusus terutama dalam kemampuan membaca, menulis dan berhitung, atau pada mata pelajaran tertentu. Fungsi dari Sekolah Dasar Inklusi untuk Anak Berkesulitan Belajar Spesifik adalah tempat belajar mengajar untuk siswa sekolah dasar umum dan yang berkesulitan belajar spesifik, yaitu disleksia, disgrafia, dan diskalkulia yang bertujuan untuk memberikan layanan pendidikan yang efektif untuk semua anak, tidak hanya yang normal, tetapi juga anak berkesulitan belajar spesifik. Konsep Multisensory Building didapat dari hasil analisis kebutuhan dan cara belajar Anak Berkesulitan Belajar Spesifik yang berbeda, yaitu memerlukan pengalaman langsung dengan materi pembelajaran, salah satunya dengan teknik multisensori, yaitu memaksimalkan pembelajaran menggunakan panca indera, yaitu dengan melihat, meraba, dan mendengar langsung serta mewadahi gerak aktif anak. Konsep yang didukung hasil analisa menghasilkan kebutuhan ruang taman belajar sebagai media belajar utama selain ruang kelas, dan diterapkan pada bentuk, material, dan warna yang mendukung proses belajar anak
Evaluasi Pelaksanaan Peraturan Daerah Kabupaten Kampar Nomor 7 Tahun 2012 Tentang Retribusi Jasa Umum (Studi Kasus Retribusi Pelayanan Pasar Air Tiris)
In order activities or activities with noncurrent current market and also Kabupaten Kampar government issued a policy through Kabupaten Kampar Regulation No. 7 of 2012 About Charges for Services Sales Manager. Charges for services Sales manager is local charges are as Payment differences The services provided by the regional government to review the interests and objectives Utilization And Sales manager can be enjoyed by private bodies. The whole object is a levy has been used markets provided by local governments exploited by private law. Subject levy or an entity is a private enjoy exploit has been used market. Singer research theory using Willian N Dunn. The analysis of data used is descriptive qualitative method. Data source the data consist of primary data obtained Namely Yang From parties Kabupaten Kampar Office Market And Market UPTD Air Tiris. While secondary data namely data sourced from office data Kabupaten Kampar Office Market And Market UPTD Air Tiris. Data was collected using observation, interview and documentasi. Data analysis is the presentation of data analysis techniques, and withdrawal keseimpulan. Research shows that the implementation of Government policy on the market levy hearts Harvesting Pasar Tiris Tiris yet reached the level of effectiveness achieved is expected to review. Factors being sub office Market Barriers hearts implementation of Government policy is the lack of awareness required to pay retribution Market restribusi hearts, facilities and infrastructure adequately market the less and less resolute hearts clerk picked retribution. Among many traders deliberately for reasons to review not pay a fee set by the Government The Kampar. In addition officers picked restribusi not expressly indicated to Trader not want to pay compulsory retribution. Traders often complain because findings Sales of the Few. In addition reasons traders want to pay retribution is not because now merchants industry knows for what restribusi requested restribusi And where are allocated by the Government of Kampar regency
Optical Instrument Thermal Control on the Large Ultraviolet/Optical/Infrared Surveyor
The Large Ultraviolet/Optical/Infrared Surveyor (LUVOIR) is a multi-wavelength observatory commissioned by NASA as one of four large mission concept studies for the Astro2020 Decadal Survey. Two concepts are under study which bound a range of cost, risk, and scientific return: an 8-meter diameter unobscured segmented aperture primary mirror and a 15-meter segmented aperture primary mirror. Each concept carries with it an accompanying suite of instruments. The Extreme Coronagraph for Living Planetary Systems (ECLIPS) is a near-ultraviolet (NUV) / optical / near-infrared (NIR) coronagraph; the LUVOIR Ultraviolet Multi-object Spectrograph (LUMOS) provides multi-object imaging spectroscopy in the 100-400 nanometer ultraviolet (UV) range; and the High Definition Imager (HDI) is a wide field-of-view near-UV / optical / near-IR camera that can also perform astrometry. The 15-meter concept also contains an additional instrument, Pollux, which is a high-resolution UV spectro-polarimeter. While the observatory is nominally at a 270 Kelvin operational temperature, the requirements of imaging in both IR and UV require separate detectors operating at different temperature regimes, each with stringent thermal stability requirements. The change in observatory size requires two distinct thermal designs per instrument. In this current work, the thermal architecture is presented for each instrument suite. We describe here the efforts made to achieve the target operational temperatures and stabilities with passive thermal control methods. Additional discussion will focus on how these instrument thermal designs impact the overall system-level architecture of the observatory and indicate the thermal challenges for hardware implementation
Centralized cytogenetic analysis of pediatric acute leukemia: results of an italian collaborative experience
Background and Objective. Cytogenetic analysis of acute leukemia yields important information which has been demonstrated to be correlated to patient survival. A reference laboratory was created in order to perform karyotype analysis on all cases of acute leukemia enrolled in the AIEOP (Associazione Italiana Emato-Oncologia Pediatrica) protocols. Methods. From January 1990 to December 1995, 1115 samples of children with ALL or AML were sent in for cytogenetic analysis. The results of cell cultures were screened in the Reference Laboratory and then the fixed metaphases were sent to one of the six cytogenetic laboratories for analysis. Results. The leukemic karyotypes of 556 patients were successfully analyzed. An abnormal clone was detected in 49% of cases of ALL and in 66% of AML. In ALL the most frequent abnormality was 9p rearrangement. Other recurrent abnormalities were t(9;22), t(4;11) and t(1;19). In AML t(8;21), t(15;17) and 11q23 rearrangement were the most frequent structural abnormalities. These findings are similar to the results obtained in other multicenter studies using a similar approach. Interpretation and Conclusions. Our data confirm the feasibility of performing cytogenetic analysis in a centralized laboratory on mailed samples of bone marrow and/or peripheral blood; this is very important considering that cytogenetic analysis of neoplastic tissue requires a special laboratory and expert staff
Optical Instrument Thermal Control on the Large Ultraviolet/Optical/Infrared Surveyor
The Large Ultraviolet/Optical/Infrared Surveyor (LUVOIR) is a multi-wavelength observatory commissioned by NASA as one of four large mission concept studies for the Astro2020 Decadal Survey. Two concepts are under study which bound a range of cost, risk, and scientific return: an 8-meter diameter unobscured segmented aperture primary mirror and a 15-meter segmented aperture primary mirror. Each concept carries with it an accompanying suite of instruments. The Extreme Coronagraph for Living Planetary Systems (ECLIPS) is a near-ultraviolet (NUV) / optical / near-infrared (NIR) coronagraph; the LUVOIR Ultraviolet Multi-object Spectrograph (LUMOS) provides multi-object imaging spectroscopy in the 100-400 nanometer ultraviolet (UV) range; and the High Definition Imager (HDI) is a wide field-of-view near-UV / optical / near-IR camera that can also perform astrometry. The 15-meter concept also contains an additional instrument, Pollux, which is a high-resolution UV spectro-polarimeter. While the observatory is nominally at a 270 Kelvin operational temperature, the requirements of imaging in both IR and UV require separate detectors operating at different temperature regimes, each with stringent thermal stability requirements. The change in observatory size requires two distinct thermal designs per instrument. In this current work, the thermal architecture is presented for each instrument suite. We describe here the efforts made to achieve the target operational temperatures and stabilities with passive thermal control methods. Additional discussion will focus on how these instrument thermal designs impact the overall system-level architecture of the observatory and indicate the thermal challenges for hardware implementation
Ischemic Stroke despite Oral Anticoagulant Therapy in Patients with Atrial Fibrillation
OBJECTIVE
It is not known whether patients with atrial fibrillation (AF) with ischemic stroke despite oral anticoagulant therapy are at increased risk for further recurrent strokes or how ongoing secondary prevention should be managed.
METHODS
We conducted an individual patient data pooled analysis of 7 prospective cohort studies that recruited patients with AF and recent cerebral ischemia. We compared patients taking oral anticoagulants (vitamin K antagonists [VKA] or direct oral anticoagulants [DOAC]) prior to index event (OACprior) with those without prior oral anticoagulation (OACnaive). We further compared those who changed the type (ie, from VKA or DOAC, vice versa, or DOAC to DOAC) of anticoagulation (OACchanged) with those who continued the same anticoagulation as secondary prevention (OACunchanged). Time to recurrent acute ischemic stroke (AIS) was analyzed using multivariate competing risk Fine–Gray models to calculate hazard ratios (HRs) and 95% confidence intervals (CIs).
RESULTS
We included 5,413 patients (median age = 78 years [interquartile range (IQR) = 71–84 years]; 5,136 [96.7%] had ischemic stroke as the index event, median National Institutes of Health Stroke Scale on admission = 6 [IQR = 2–12]). The median CHA2DS2‐Vasc score (congestive heart failure, hypertension, age≥ 75 years, diabetes mellitus, stroke/transient ischemic attack, vascular disease, age 65–74 years, sex category) was 5 (IQR = 4–6) and was similar for OACprior (n = 1,195) and OACnaive (n = 4,119, p = 0.103). During 6,128 patient‐years of follow‐up, 289 patients had AIS (4.7% per year, 95% CI = 4.2–5.3%). OACprior was associated with an increased risk of AIS (HR = 1.6, 95% CI = 1.2–2.3, p = 0.005). OACchanged (n = 307) was not associated with decreased risk of AIS (HR = 1.2, 95% CI = 0.7–2.1, p = 0.415) compared with OACunchanged (n = 585).
INTERPRETATION
Patients with AF who have an ischemic stroke despite previous oral anticoagulation are at a higher risk for recurrent ischemic stroke despite a CHA2DS2‐Vasc score similar to those without prior oral anticoagulation. Better prevention strategies are needed for this high‐risk patient group. ANN NEUROL 202
Risiken im Lebenszyklus: Theorie und Evidenz
Der einzelne Mensch ist im Lebensverlauf erheblichen biometrischen, ökonomischen, familiären und politischen Risiken ausgesetzt. Viele meinen, diese wären in den letzten Jahren größer geworden. Haben wir die richtigen Institutionen, um diese Risiken effizient abzudecken? Unter Institutionen verstehen wir individuelles Sparen, familiäre Hilfe, private Versicherungen und schließlich den Staat mit seinen Sozialversicherungen. Wo und wann funktionieren diese Institutionen? Wo und wann nicht? Was muss man tun, um sie zu verbessern? Wie sieht modernes "Social Risk Management" aus? Der erste Teil dieses Übersichtsbeitrags skizziert die wirtschaftstheoretischen Grundlagen des Sparverhaltens, der Portefeuillewahl und der Versicherungsnachfrage. Im Hauptteil werden die empirischen Befunde gesammelt, um im dritten Teil wirtschaftspolitische Schlussfolgerungen zu ziehen
Housing Busts and Household Mobility
Using two decades of American Housing Survey data from 1985 to 2005, we estimate the influence of negative home equity and rising mortgage interest rates on household mobility. We find that both factors lead to lower, not higher, mobility rates over time. The effects are economically large - mobility is almost 50 percent lower for owners with negative equity in their homes. This finding does not imply that current concerns over defaults and homeowners having to relocate are entirely misplaced. It does indicate that, in the past, the mortgage lock-in effects of these two factors were dominant over time. Policymakers may wish to begin considering the consequences of mortgage lock-in and reduced household mobility because they are quite different from the consequences associated with default and higher mobility
- …