Interference at the Single Photon Level Along Satellite-Ground Channels

Quantum interference arising from superposition of states is a striking evidence of the validity of Quantum Mechanics, confirmed in many experiments and also exploited in applications. However, as for any scientific theory, Quantum Mechanics is valid within the limits in which it has been experimentally verified. In order to extend such limits, it is necessary to observe quantum interference in unexplored conditions such as moving terminals at large distance in Space. Here we experimentally demonstrate single photon interference at a ground station due to the coherent superposition of two temporal modes reflected by a rapidly moving satellite thousand kilometers away. The relative speed of the satellite induces a varying modulation in the interference pattern. The measurement of the satellite distance in real time by laser ranging allowed us to precisely predict the instantaneous value of the interference phase. We then observed the interference patterns with visibility up to $67\%$ with three different satellites and with path length up to 5000 km. Our results attest the viability of photon temporal modes for fundamental tests of Physics and Quantum Communications in Space.Comment: Version accepted for publication in Phys. Rev. Let

Towards Quantum Communication from Global Navigation Satellite System

Satellite-based quantum communication is an invaluable resource for the realization of a quantum network at the global scale. In this regard, the use of satellites well beyond the low Earth orbits gives the advantage of long communication time with a ground station. However, high-orbit satellites pose a great technological challenge due to the high diffraction losses of the optical channel, and the experimental investigation of such quantum channels is still lacking. Here, we report on the first experimental exchange of single photons from Global Navigation Satellite System at a slant distance of 20000 kilometers, by exploiting the retroreflector array mounted on GLONASS satellites. We also observed the predicted temporal spread of the reflected pulses due to the geometrical shape of array. Finally, we estimated the requirements needed for an active source on a satellite, aiming towards quantum communication from GNSS with state-of-the-art technology.Comment: Revte

Large-scale optical interferometry in general spacetimes

We introduce a convenient formalism to evaluate the frequency-shift affecting a light signal propagating on a general curved background. Our formulation, which is based on the laws of geometric optics in a general relativistic setting, allows to obtain a transparent generalization of the Doppler frequency-shift without requiring to perform Local Lorentz transformations. It is easily applicable to stationary spacetimes, and in particular to the near-Earth experiments where geometry is described in the parametrized post-Newtonian approximation. We apply our recipe to evaluate the phase-shift arising in large-scale optical interferometric experiments, as the optical version of the Colella-Overhauser-Werner experiment.Comment: 8 pages, 3 figure

Proposal for an Optical Test of the Einstein Equivalence Principle

The Einstein Equivalence Principle (EEP) underpins all metric theories of gravity. Its key element is the local position invariance of non-gravitational experiments, which entails the gravitational red-shift. Precision measurements of the gravitational red-shift tightly bound violations of the EEP only in the fermionic sector of the Standard Model, however recent developments of satellite optical technologies allow for its investigation in the electromagnetic sector. Proposals exploiting light interferometry traditionally suffer from the first-order Doppler effect, which dominates the weak gravitational signal necessary to test the EEP, making them unfeasible. Here, we propose a novel scheme to test the EEP, which is based on a double large-distance optical interferometric measurement. By manipulating the phase-shifts detected at two locations at different gravitational potentials it is possible to cancel-out the first-order Doppler effect and observe the gravitational red-shift implied by the EEP. We present the detailed analysis of the proposal within the post-Newtonian framework and the simulations of the expected signals obtained by using two realistic satellite orbits. Our proposal to overcome the first-order Doppler effect in optical EEP tests is feasible with current technology.Comment: manuscript improve

Extending Wheeler's delayed-choice experiment to Space

Gedankenexperiments have consistently played a major role in the development of quantum theory. A paradigmatic example is Wheeler's delayed-choice experiment, a wave-particle duality test that cannot be fully understood using only classical concepts. Here, we implement Wheeler's idea along a satellite-ground interferometer which extends for thousands of kilometers in Space. We exploit temporal and polarization degrees of freedom of photons reflected by a fast moving satellite equipped with retro-reflecting mirrors. We observed the complementary wave-like or particle-like behaviors at the ground station by choosing the measurement apparatus while the photons are propagating from the satellite to the ground. Our results confirm quantum mechanical predictions, demonstrating the need of the dual wave-particle interpretation, at this unprecedented scale. Our work paves the way for novel applications of quantum mechanics in Space links involving multiple photon degrees of freedom.Comment: 4 figure

Postselection-loophole-free Bell violation with genuine time-bin entanglement

Entanglement is an invaluable resource for fundamental tests of physics and the implementation of quantum information protocols such as device-independent secure communications. In particular, time-bin entanglement is widely exploited to reach these purposes both in free-space and optical fiber propagation, due to the robustness and simplicity of its implementation. However, all existing realizations of time-bin entanglement suffer from an intrinsic postselection loophole, which undermines their usefulness. Here, we report the first experimental violation of Bell's inequality with "genuine" time-bin entanglement, free of the postselection loophole. We introduced a novel function of the interferometers at the two measurement stations, that operate as fast synchronized optical switches. This scheme allowed to obtain a postselection-loophole-free Bell violation of more than nine standard deviations. Since our scheme is fully implementable using standard fiber-based components and is compatible with modern integrated photonics, our results pave the way for the distribution of genuine time-bin entanglement over long distances.Comment: RevTe

Insulin resistance, diabetic kidney disease, and all-cause mortality in individuals with type 2 diabetes. a prospective cohort study

BACKGROUND: It is unclear whether insulin resistance (IR) contributes to excess mortality in patients with type 2 diabetes independent of diabetic kidney disease (DKD), which is strongly associated with IR and is a major risk factor for cardiovascular disease (CVD), the main cause of death in these individuals. We tested this hypothesis in patients with type 2 diabetes from the Renal Insufficiency And Cardiovascular Events Italian Multicentre Study.METHODS: This observational, prospective, cohort study enrolled 15,773 patients with type 2 diabetes attending 19 Italian Diabetes Clinics in 2006-2008. Insulin sensitivity was assessed as estimated glucose disposal rate (eGDR), which was validated against the euglycaemic-hyperinsulinemic clamp technique. Vital status on October 31, 2015, was retrieved for 15,656 patients (99.3%). Participants were stratified by eGDR tertiles from T1 (≥ 5.35mg/kg/min) to T3 (≤ 4.14mg/kg/min, highest IR).RESULTS: CVD risk profile was worse in T2 and T3 vs T1. eGDR tertiles were independently associated with micro- and macroalbuminuria and the albuminuric DKD phenotypes (albuminuria with preserved or reduced estimated glomerular filtration rate [eGFR]) as well as with eGFR categories or the nonalbuminuric DKD phenotype. Over a 7.4-year follow-up, unadjusted death rates and mortality risks increased progressively across eGDR tertiles, but remained significantly elevated after adjustment only in T3 vs T1 (age- and gender- adjusted death rate, 22.35 vs 16.74 per 1000 person-years, p<0.0001, and hazard ratio [HR] adjusted for multiple confounders including DKD, 1.140 [95% confidence interval [CI], 1.049-1.238], p=0.002). However, eGDR was independently associated with mortality in participants with no DKD (adjusted HR, 1.214 [95% CI, 1.072-1.375], p=0.002) and in those with nonalbuminuric DKD (1.276 [1.034-1.575], p=0.023), but not in those with the albuminuric DKD phenotypes. Moreover, the association was stronger in males and in younger individuals and was observed in those without but not with prior CVD, though interaction was significant only for age.CONCLUSIONS: The proxy of insulin sensitivity eGDR predicts all-cause mortality in type 2 diabetes, independent of confounders including DKD. However, the impact of IR in individuals with albuminuric DKD may be mediated by its relationship with albuminuria.TRIAL REGISTRATION: ClinicalTrials.gov , NCT00715481, retrospectively registered 15 July 2008

Independent association of atherogenic dyslipidaemia with all-cause mortality in individuals with type 2 diabetes and modifying effect of gender. a prospective cohort study

Atherogenic dyslipidaemia has been implicated in the residual risk for cardiovascular morbidity and mortality, which remains despite attainment of LDL cholesterol goals especially in individuals with type 2 diabetes. However, its relationship with all-cause death has not been sufficiently explored. This analysis evaluated the independent association of increased triglycerides and triglyceride:HDL cholesterol ratio (TG:HDL) and decreased HDL cholesterol with total mortality and the possible modifying effect of gender in a large cohort of patients with type 2 diabetes

Intermodal quantum key distribution field trial with active switching between fiber and free-space channels

Intermodal quantum key distribution enables the integration of fiber networks and free-space channels, which are both necessary elements for the development of a global quantum network. We present a field trial of an intermodal quantum key distribution system - comprised of two polarization-based transmitters and a single receiver - in which the active channel is alternately switched between a free-space link of 620 m and a 17km-long deployed fiber in the metropolitan area of Padova. The performance of the free-space channel is evaluated against the atmospheric turbulence strength. The field trial lasted for several hours in daylight conditions, attesting the intermodal functionality between fiber and free-space channels. Our switching system represents a cost-effective solution for a trusted quantum key distribution network, reducing the number of necessary devices in different network topologies