15 research outputs found

    BL ニ ヨル Android アプリケーション カイハツ ジュギョウ

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    Android アプリケーション開発授業をProject Based Learning(PBL)で実施した授業実践報告である。アプリケーション開発の授業では実際のアプリケーションがどのように開発されるのか実感を持って理解されていないことが多い。また、開発には多様な役割のメンバーが関わるが、具体的にどのように作業を分担するも理解されていないことが多い。開発工程を実感するためには実際に開発を経験することが最良の処方箋であろう。そのため、PBL によるAndroid アプリケーションを開発する授業を企画・実践した。A class for Android application development through Project Based Learning (PBL) is reported. It is not often understood how real application is developed by the class of the application development with an actual feeling. In addition, the members of a variety of roles is concerned with development, but is not often understood how the work is shared. It will be really the best method to experience development to realize a development process. Therefore a class to develop Android application by PBL is planned and practiced

    ショウホク タンキダイガク ニ オケル KNOPPIX ノ キョウイク リヨウ

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    KNOPPIX is one of the bootable Linux from CD-ROM drive, and has lately attracted considerable attention from the various education system.This paper investigate the feature of KNOPPIX at first, then KNOPPIX is shown as a effective solution for information education from elementary education to higher education. This paper also investigate how KNOPPIX has been used in Shohoku College, and the plan in the next year how to promote utilization of KNOPPIX is expressed

    Environmental Consciouness in Japan on Materials and Products -Analysis of Eco-MCPS, a Web-database for Ecomaterials

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    Eco-MCPS database is a web-based database system that contains data of environment-conscious materials,components, products, and services. The text data compiled in the Eco-MCPS and the access log data of Eco-MCPS were subjected to data mining. Word-frequency analysis and dependency parsing analysis were applied tothe data to obtain the frequently used terms and their situations of use. By analyzing the access log, the interestof the visitors accessed to the web-site can be understood. The results showed that eco-products\u27 environmental performances are realized by the use of environment-friendly components or materials. The page views, which represent the visitors\u27 interest, were related with the frequently used term in the comments of Eco-MCPS to showthe social consciousness on environment-friendly products. By further analyzing the access log, it was found thatthe word search rank followed the Zipf\u27s Law

    Development and validation of the Japanese version of the Bedtime Procrastination Scale (BPS-J)

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    Abstract Background The average sleep duration of Japanese people is shorter than that of people from other countries, and bedtime procrastination is suspected to be one of the factors contributing to this issue. This study aimed to develop and validate the Japanese version of the Bedtime Procrastination Scale (BPS-J). Methods The BPS-J was developed through procedures including the translation and back-translation of the scale, cognitive interviews with 100 participants who reported having experiences of being diagnosed with insufficient sleep syndrome (ISS) or receiving treatment for ISS using open-ended online questionnaires, and expert checking. To investigate the scale’s validity and reliability, an online survey was conducted with daytime workers aged 20 − 65 years without a history of sleep disorders other than ISS. Half the participants were retested using the same survey after 14 days. Participants’ responses to the Brief Self-Control Scale (BSCS), General Procrastination Scale (GPS), and Munich ChronoType Questionnaire (MCTQ), and data on sleep-related variables such as sleep duration on workdays and the days per week of fatigue or sleep loss, sex, and age, were collected. Results We analyzed data from 574 participants to assess scale validity. We then analyzed data from 280 participants to determine test–retest reliability. Confirmatory factor analyses revealed that the two-factor model without Item 2 was most suitable for the BPS-J, unlike other language versions. Regardless of the full-item model or the model with Item 2 eliminated, sufficient reliability and significant correlations with the BSCS, GPS, MCTQ, and sleep-related variables such as sleep duration per night on work days, days per week of feeling fatigued, and days per week of sleep loss were observed. Logistic and linear regressions showed that the relationships between the BPS-J, sleep-related variables, and MCTQ were maintained after adjusting for sex and age. Conclusion The BPS-J had sufficient validity and reliability. Further, eliminating Item 2 from the original version of the BPS strengthened the ability to survey Japanese daytime workers

    Lack of association between intact/deletion polymorphisms of the APOBEC3B gene and HIV-1 risk.

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    The human APOBEC3 family of proteins potently restricts HIV-1 replication APOBEC3B, one of the family genes, is frequently deleted in human populations. Two previous studies reached inconsistent conclusions regarding the effects of APOBEC3B loss on HIV-1 acquisition and pathogenesis. Therefore, it was necessary to verify the effects of APOBEC3B on HIV-1 infection in vivo.Intact (I) and deletion (D) polymorphisms of APOBEC3B were analyzed using PCR. The syphilis, HBV and HCV infection rates, as well as CD4(+) T cell counts and viral loads were compared among three APOBEC3B genotype groups (I/I, D/I, and D/D). HIV-1 replication kinetics was assayed in vitro using primary cells derived from PBMCs.A total of 248 HIV-1-infected Japanese men who have sex with men (MSM) patients and 207 uninfected Japanese MSM were enrolled in this study. The genotype analysis revealed no significant differences between the APOBEC3B genotype ratios of the infected and the uninfected cohorts (p = 0.66). In addition, HIV-1 disease progression parameters were not associated with the APOBEC3B genotype. Furthermore, the PBMCs from D/D and I/I subjects exhibited comparable HIV-1 susceptibility.Our analysis of a population-based matched cohort suggests that the antiviral mechanism of APOBEC3B plays only a negligible role in eliminating HIV-1 in vivo

    APOBEC3 mRNA expression levels depending on <i>APOBEC3B</i> genotype.

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    <p>(A) Comparison of mRNA expression levels of APOBEC3 in CD4<sup>+</sup> cells isolated from intact (I/I), hemizygous (I/D) and deletion (D/D) individuals of healthy donors. The relative mRNA expression levels of APOBEC3A (I/I, n = 8; I/D, n = 4; D/D, n = 4), APOBEC3B (I/I, n = 11; I/D, n = 7; D/D, n = 5), APOBEC3C (I/I, n = 12; I/D, n = 7; D/D, n = 5), APOBEC3DE (I/I, n = 11; I/D, n = 9; D/D, n = 5), APOBEC3F (I/I, n = 12; I/D, n = 7; D/D, n = 5), APOBEC3G (I/I, n = 12; I/D, n = 7; D/D, n = 5), and APOBEC3H (I/I, n = 6; I/D, n = 7; D/D, n = 4) were determined using quantitative RT-PCR and were normalized to GAPDH. The red (I/I) or gray (D/D) dots represent the expression levels of donors whose PBMCs were used for the <i>in vitro</i> kinetics of HIV-1 replication and infectivity in Figure. 3. The p values were calculated using Welch’s <i>t</i>-test. The error bar represents the standard error of the mean (SEM). (B) APOBEC3A (A3A) and APOBEC3G (A3G) mRNA expression levels under basal conditions (Ctrl) and after stimulation with 100 U/ml (+IFN-α) of interferon (IFN)-α in CD14<sup>+</sup> MDMs isolated from healthy control subjects. The black and white bars indicate D/D (n = 3) and I/I (n = 4) individuals, respectively. The <i>p</i> values were calculated with the Mann-Whitney <i>U</i>-test. The error bars represent the standard deviation. <i>n.d.</i>, not detected. Ct, cycle threshold. <i>n.s.</i>, not significant (<i>p</i> = 0.4 for both cases).</p

    Analysis of effects of genotype on parameters of HIV disease progression in the HIV-1-infected cohort.

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    <p>(A) Changes in CD4<sup>+</sup> T cell counts (cells/μl/day) (n = 202). (B) Changes in HIV-1 RNA levels (log<sub>10</sub> copies/ml/day) in plasma (n = 202). The box plots show data between the 25th and 75th percentiles with central horizontal lines representing the median, and with whiskers showing the 10th and 90th percentiles. The open circles represent outliers with data >1.5-fold of the interquartile range. All the p values were determined using the Kruskal-Wallis test.</p
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