Three-Dimensional Printed Custom-Made Prostheses after Partial Scapulectomy: A Case Report

Abstract: This case study focuses on scapula reconstruction using three-dimensional printing in a patient with low-grade osteosarcoma. Malignant tumors originating from the scapula often lead to destructive surgery, with poor functional status and quality of life for the patients. Using custom prosthetic technology through three-dimensional printing could be a possible solution for reconstruction with greater long-term functional outcomes. This study aims to assess the functional outcomes of the reconstruction. A 39-year-old patient with low-grade central osteosarcoma involving the lateral two-thirds of the scapula underwent a custom prosthetic reconstruction. The patient subsequently followed a rehabilitation protocol for 12 months. The results indicate that even though there was a slight decrease in the range of movement, and an increase in the disabilities of the arm, shoulder, and hand (DASH) score, no relevant increase in activities of daily living (ADL) disability was present at follow-up. The patient returned to carry out his daily activities without pain and with a minimal functional reduction in movement. In conclusion, three-dimensional prosthetic reconstruction is a valid alternative for scapula reconstruction, allowing excellent functional and aesthetic results in oncological cases

Tre carotaggi presso l'ex convento degli Eremitani a Padova

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Lotto 2a, Sito 3: un villaggio dell’età del Bronzo a Montecchio Precalcino

Nel 2012, nel corso dei lavori di realizzazione della Superstrada Pedemontana Veneta, tra i comuni di Sarcedo e Montecchio Precalcino (VI) sono state indagate due aree insediative tra loro distanti 500 m ca., inquadrabili nell’età del Bronzo medio-recente: in entrambe si è rilevata la presenza di strutture a carattere abitativo, fossati e silos e di materiale ceramico e litico in dispersion

Padova, area ex CNR in Zona industriale. Tombe di et\ue0 romana nel territorio ad est della citt\ue0

Padova, Et\ue0 Romana, Archeologia Urban

Grading in Myxofibrosarcoma of the Extremities Can Predict Survival and Local Control

Background: The aim of this retrospective analysis is to understand the natural history of myxofibrosarcoma (MFS), in particular whether the prognosis can be influenced by histologic grade. Methods: We reviewed 229 adult patients with primary MFS of the limbs. We analyzed disease-specific survival (overall survival [OS]) and local recurrence (LR). Results: Median age was 70 years (range, 19-92). Sixteen (7.0%) were grade 1, 38 (16.6%) grade 2, and 175 (76.4%) grade 3. A worse OS was found in grade 3 MFS (73.1%) than in grade 2 and 1 MFS (91.9 and 100%, respectively) at 5 years (p = 0.031). Locally recurred MFS had a worse OS (p = 0.018). A better LR-free rate (100% at 5 years) was observed in grade 1 MFS; however, a similar rate was observed between grade 2 and 3 tumors (77.1 and 80.0% at 5 years, respectively, p = 0.412). Conclusions: Grade 3 MFS has the worst prognosis. Grade 1 MFS have the lowest risk of LR. These data could help identify a high-risk patient group, thus selecting a more careful follow-up for higher-risk patients. Since MFS mostly affects the elderly population, it might be useful to reserve adjuvant treatments (radiotherapy and chemotherapy) to higher-risk patients

Total hip arthroplasty in hereditary multiple exostosis patients: literature review and evaluation of 10 cases

Background: Acquired hip deformities in patients affected by hereditary multiple exostosis (HME) may incur in early hip osteoarthritis and functional limitation requiring primary total hip arthroplasty (THA). Characteristic coxo-femoral joint dysmorphisms in HME may pose a challenge for the orthopaedic surgeon. Here we report our experience in a series of patients with HME treated in our hospital with THA. Methods: With a mean follow-up of 5 years, 10 primary THAs were reviewed; proximal femur deformities, acetabular dysplasia and joint osteoarthritis has been assessed through x-rays and CT-scan evaluation. In all cases hemispheric press-fit cups were used; 4 stem had metaphyseal engagement, 5 had proximal diaphyseal engagement and 1, with anatomical geometry, had metaphyseal fixation. 2 cases required stem cementation, 3 modular neck and 1 lateralised. The clinical data, complications and clinical outcomes, were recorded and analysed. Results: The mean Harris Hip Score (HHS) increased from 34 preoperative to 86 postoperative; preoperative mean neck shaft angle (NSA) was 150°, head/neck ratio 0.6, offset 31 mm; Wiberg angle 28°, Sharp angle 38°, 1 patient had subluxation grade 4 according to Crowe, 8 hips showed osteoarthritis (Tönnis grade ⩾2); 5 femurs were classified as Dorr type C, 2 as type B and 3 as type A. Perioperative complications were not observed. Conclusions: Primary THA in HME significantly improved clinical and functional outcomes. Press-fit cup fixation together with metaphyseal and proximal diaphyseal stem engagement on reliable bone quality femur, represents a valid option in HME patients with normal acetabular morphology, wide broaden neck and valgus NSA

Glycerophosphate acetyltransferase activity in perfused liver of normal and hyperlipemic rats: glucagon effect.

none7noneTessari P;Meneghel A;Avogaro A;Duner E;Del Prato S;Tuzzato M;Tiengo ATessari, Paolo; Meneghel, A; Avogaro, Angelo; Duner, E; Del Prato, S; Tuzzato, M; Tiengo, Antoni

Glycerophosphate acetyltransferase activity in perfused liver of normal and hyperlipemic rats: glucagon effect.

Mitochondrial glycerophosphate-acetyltransferase activity (GPAT) was determined in the isolated and perfused liver of diet-induced hyperlipemic rats, and was found to be significantly increased compared to normal rats, A positive correlation existed between hepatic triglyceride output and GPAT. Perfusion of 10(-5) M glucagon induced a significant reduction in GPAT levels. It is suggested that the lipid-lowering action of glucagon may be mediated also through an inhibition of GPAT activity

La città invisibile. Padova preromana. Trent'anni di scavi e ricerche.

Il volume presenta un aggiornamento su Padova preromana dal IX al II secolo a.C., con saggi di sintesi sulla storia della ricerca,i probelmi geomorfologico,l'inquadramento dell'ambiente naturale, il tema dello sviluppo urbanistico e topografico. La suddivisione in capitoli sull'abitato, lemanifestazioni delculto ele necropoli sono introdotti da un saggio di sintesi che tiene conto di quanto illustrato analiticamente nelle schede sito. Sono riuniti tutti i siti di rinvenimento con una cartografia esaustiva aggiornata al 2003