Éxito profesional

The theoretical concepts of profession, success and professional success share a common characteristic, they can be describe in objective or subjective terms. With regard to career success, in 1937, E.C. Hughes established this theoretical difference; nevertheless, studies on this subject, traditionally, have evaluated professional success in objective terms. More recently, the theoretical tendency recognizes objective– subjective duality in professional success, the interdependence between these two elements and it indicates that, they must be treated integrally on professional success studies

Squalene: A Trove of Metabolic Actions

Squalene is present in high concentration in the liver of certain sharks and in small concentrations in olive oil. Previous studies showed that its administration decreases hepatic steatosis in male Apoe-knockout mice, but these changes might be complex. Transcriptomics, using DNA microarrays, and proteomics from mitochondrial and microsomal fractions, analyzed by 2D-DIGE and mass spectrometry, were used in these mice that received 1 g/kg/day squalene for 10 weeks. Squalene administration significantly modified the expression of genes such as lipin 1 (Lpin1) and thyroid hormone responsive (Thrsp). Changes in methionine adenosyltransferase 1 alpha (Mat1α), short-chain specific acyl-CoA dehydrogenase (Acads), and thioredoxin domain–containing protein 5 (Txndc5) expressions were consistent with their protein levels. Their mRNA levels were associated with hepatic fat content. These results suggest that squalene action involves changes in hepatic gene expression associated with its anti-steatotic properties. This approach shows new connections between nutrition and gene expression since Txndc5, a gene with unknown biological function, was upregulated by squalene administration. Overall, this nutrigenomic approach illustrates the effects of squalene and provides further support to the idea that not all monounsaturated fatty acid–containing oils behave similarly. Therefore, selection of cultivars producing olive oils enriched in this compound will be a plus

Mejorando la convivencia en los centros [Texto impreso]

En la cub.: 1

Percepción del nivel de conocimientos y grado de implantación de los cuidados centrados en el desarrollo por parte los enfermeros en la Unidad de Cuidados Intensivos Neonatales del Hospital Universitario de Canarias.

La Organización Mundial de la Salud considera la prematuridad como primera causa de muerte neonatal, y, por los factores que la propician, también se considera un problema de Salud Pública. Dada la inmadurez general que caracteriza a los neonatos pretérmino, la incidencia de comorbilidades es elevada. Los Cuidados Centrados en el Desarrollo son un conjunto de intervenciones que modifican el ambiente e implican a la familia con el fin de preservar el neurodesarrollo del bebé y prevenir dichas complicaciones. A través de estas intervenciones se asegura un cuidado integral del niño y su familia, disminuyendo el riesgo de desarrollo de secuelas. Para que estos cuidados sean de calidad se precisa de la implicación de todo el personal de la unidad y de las instituciones pertinentes. El objetivo principal de este proyecto es conocer la percepción del nivel de conocimientos y grado de implantación de los Cuidados Centrados en el Desarrollo por parte de los enfermeros en la Unidad de Cuidados Intensivos Neonatales del Hospital Universitario de Canarias. La muestra estará formada por la totalidad de los enfermeros de la unidad y para la recogida de los datos se utilizará un cuestionario anónimo que recoge todas las variables sociodemográficas y de estudio del proyecto. Las conclusiones permitirán descubrir la percepción del nivel de conocimientos que tiene el personal de enfermería sobre esta dinámica de cuidados, el grado de implantación que existe actualmente en la unidad, así como los aspectos que impiden su total establecimiento.The World Health Organization considers prematurity as the leading cause of neonatal death, and due to the factors that promote it, it is also considered a Public Health problem. Given the general immaturity that characterizes preterm infants, the incidence of comorbidities is high. Developmental Care is a set of interventions that modify the environment and involve the family in order to preserve the baby's neurodevelopment and complications. Through these interventions, comprehensive care of the child and his family is ensured, reducing the risk of development of sequelae. For these cares to be of quality, the involvement of all the personnel of the unit and of the pertinent institutions is required. The main objective of this project is to know the perception of the level of knowledge and degree of implementation of Development-Centered Care by nurses in the Neonatal Intensive Care Unit of the Hospital Universitario de Canarias. The sample will be made up of all the unit's nurses and an anonymous questionnaire will be used to collect the data that collects all the sociodemographic and study variables of the project. The conclusions will make it possible to discover the perception of the level of knowledge that the nursing staff has about this dynamic of care, the degree of implementation that currently exists in the unit, as well as the aspects that prevent its total establishment

Mastitomics, the integrated omics of bovine milk in an experimental model of Streptococcus uberis mastitis: 1. High abundance proteins, acute phase proteins and peptidomics

A peptidomic investigation of milk from an experimental model of Streptococcus uberis mastitis in dairy cows has incorporated a study of milk high abundance and acute phase (APP) proteins as well as analysis of low molecular weight peptide biomarkers. Intramammary infection (IMI) with S. uberis caused a shift in abundance from caseins, β-lactoglobulin and α-lactalbumin to albumin, lactoferrin and IgG with the increase in lactoferrin occurring last. The APP response of haptoglobin, mammary associated serum amyloid A3 and C-reactive protein occurred between 30–48 hours post challenge with peak concentrations of APPs at 72–96 hours post challenge and declined thereafter at a rate resembling the fall in bacterial count rather than the somatic cell count. A peptide biomarker panel for IMI based on capillary electrophoresis and mass spectrometry was developed. It comprised 77 identified peptides (IMI77) composed mainly of casein derived peptides but also including peptides of glycosylation dependent cell adhesion molecule and serum amyloid A. The panel had a biomarker classification score that increased from 36 hour to 81 hour post challenge, significantly differentiating infected from non-infected milk, thus suggesting potential as a peptide biomarker panel of bovine mastitis and specifically that of S. uberis origin. The use of omic technology has shown a multifactorial cross system reaction in high and low abundance proteins and their peptide derivatives with changes of over a thousand fold in analyte levels in response to S. uberis infection

Reflexiones preliminares sobre el sistema de educación superior en Colombia y su papel en el contexto de un mundo globalizado

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Éxito profesional

The theoretical concepts of profession, success and professional success share a common characteristic, they can be describe in objective or subjective terms. With regard to career success, in 1937, E.C. Hughes established this theoretical difference; nevertheless, studies on this subject, traditionally, have evaluated professional success in objective terms. More recently, the theoretical tendency recognizes objective– subjective duality in professional success, the interdependence between these two elements and it indicates that, they must be treated integrally on professional success studies