Early Detection of Bronchial Lesions Using System of Autofluorescence Endoscopy (SAFE) 1000

Recently several endoscopic fluorescence detection systems have been developed. In some of them, laser light was used for the excitation of autofluorescence, and sophisticated techniques were also necessary to amplify the fluorescence signal as well

High Precision Pipeline Leak Detection and Localization Using Negative Pressure Wave Technique: An Application in a Real Field Case Study

One of the most important aspects of oil and gas production is the safe and efficient fluid transportation using pipelines. Pipelines transporting various fluids are the most efficient but are susceptible to failure and leaks. These leaks can come about through natural disaster, as well as from general wear from the pipes that could result in major environmental and economic problems. The ability to detect leaks with speed and accuracy, as well as locating these leaks within a narrow range, will aid with the maintenance response. Hasty responses will minimize the revenue loss and reduce potential environmental impact but bring about various computational challenges. Among all the leak detection techniques used in the industry the Negative Pressure Wave (NPW) is the most popular and cost-effective technique. Pressure analysis of several transducers makes it possible to both identify and locate the leak. However, there are several challenges to analyzing such pressure transducer data. It is extremely noisy (low quality data), there is a high noise to data ratio, requiring computationally expensive processes to denoise and make legible. Secondly, the initial pressure drop caused by the leak will dissipate quickly and the negative pressure wave decays as the system reaches a new equilibrium condition. The pressure data is also convoluted with both known and spontaneous events (i.e., multiple pumps and possible leak events). Finally, the robustness of the system needs to be verified to avoid complications and extra cost associated with false leak events detected. To remedy this issue, a new workflow is designed and applied in both complex real field flow networks in Texas and further assessed in a complex system with multiple and random leak and pump events. The new workflow incorporates i) data preprocessing including data cleansing, normalization and denoising; ii) developing dynamic pressure control limit lines for detecting and deconvolution of the pump events from actual leak events; iii) Performing multiple transducer analysis techniques to reduce and eliminate the possibility of the false events; iv) developing flow simulation software built on open-source Python package called WNTR to generate synthetic leak scenarios v) Finally, constructing a dashboard using the Python programming language and the Plotly open source graphing libraries for near real time visualization of different transducers response, quality check and verification of leak events and finally locating the leak event on the flow network map. Three months of data collected from a flow network is analyzed and one leak event is identified and confirmed with the operator. The leak occurred in the close vicinity of in-line pressure transducer #19 and the exact location was identified. The workflow is tested on a real network with synthetic leaks and high precision 10 and 1 millisecond recording and leak events are detected with 10-meter accuracy. The workflow showed great capability to be integrated with the SCADA system and being able to be used for near real time leak detection

Probe-based confocal laser endomicroscopy in COVID-19

Probe-based confocal laser endomicroscopy (pCLE) is a method that produces microscopic imaging of a lung tissue during bronchoscopy. We report a case ot a patient with negative nasopharyngeal swabs and suspected lung cancer who underwent pCLE. The diagnosis of COVID-19 was confirmed by PCR analyses of lavage fluid and transbrohial biopsy. The pCLE image shows density of alveolar thickened fibres, disorganization of elastin network, and multiple large drops of intraalveolar secretions. As far as we know, this is the first pCLE image discribed in patient with COVID-19 at that moment

Fleurs d’autisme au jardin du Docteur Gachet à Auvers-sur-Oise

Représentés par Paul Cézanne, Camille Pissarro ou Vincent Van Gogh, la maison et le jardin du docteur Gachet à Auvers-sur-Oise sont inscrits à l’Inventaire supplémentaire des monuments historiques depuis 1991. Médecin spécialiste de la mélancolie, adepte de l’homéopathie, collectionneur éclectique et ami des artistes, peintre et graveur lui-même à ses heures, Paul-Ferdinand Gachet (1828-1909) est une figure marquante de la fin du xixe siècle. Devenue propriété du conseil départemental du Val-d’Oise en 1996, cette maison est ouverte au public depuis 2003 et reçoit en moyenne 12 000 visiteurs par an. Arrivé à l’Action culturelle du département pour accompagner les travaux de restitution du jardin en 2002, j’en assure aujourd’hui le suivi artistique. Une expérience singulière a réuni ce jardin à un groupe d’apprentis du Centre d’initiation au travail et à la vie sociale (CITVS) de Jouy-le-Moutier, une émanation de « La Clé pour l’autisme », institut médico-éducatif rattaché à la fondation John Bost. C’est cette aventure en quatre temps que je me propose de relater. Une première visite au CITVS m’a permis de découvrir, outre les apprentis et leurs encadrants, les installations techniques et le terrain d’expérimentation horticole. Tous sont venus ensuite visiter le jardin d’Auvers où je leur ai donné l’essentiel des informations concernant le docteur Gachet, sa personnalité originale, ses relations artistiques et bien sûr, le passage de Van Gogh. Puis nous nous sommes tous déplacés à Paris pour découvrir les tableaux provenant de la donation des héritiers Gachet à l’État. Les apprentis ont, enfin, cultivé des végétaux qu’ils sont venus planter sur place, en lien avec les références picturales qu’ils ont pu percevoir.Painted by Paul Cézanne, Camille Pissaro and Vincent Van Goch, the house and garden of Docteur Gachet at Auvers-sur-Oise were inscribed as historic monuments in 1991. Paul-Ferdinand Gachet (1828-1909) was a doctor who specialised in melancholy. He was an adept of homeopathy, an eclectic collector and friend of artists and even a painter and engraver himself when he had the time. He was, in short, a striking personality of the late nineteenth century. His house was acquired by the council of the Val d’Oise department in 1996 and opened to the public in 2003. It has about 12,000 visitors a year. I joined the cultural services of the department in 2002, in order to follow the work being done to make the garden accessible to the public. I am responsible today for the site’s artistic contents. An original initiative has set up a link between the garden and a group of apprentices from the centre for introduction to work and to social life (Centre d’initiation au travail et à la vie sociale - CITVS) at Jouy-le-Moutier, a centre based on the ‘Keys for autism’, a medical and educational institute associated with the John Bost foundation. The article here is an account of that initiative in four chapters. A first visit to the CITVS allowed me to meet the apprentices and the centre’s staff and to see the technical installations and their experimental garden. The group then visited Auvers-sur-Oise where I gave them some basic information about Docteur Gachet, his original personality, his friendships with various artists and, of course, Van Gogh’s stay at Auvers. Then, together, we visited Paris where we were able to see some of the paintings that Docteur Gachet’s heirs donated to the French State. And, finally, the apprentices came to the garden at Auvers to plant various plants corresponding with some of the paintings they had seen

Artisans's advertising in XXth century France

Artisans are usually considered as businessmen who don't advertise. The way the dvertising business organized itself at the beginning of the 20th century seems to relegate them out of his field. However, craftsmen do seem to use some kind of commercial communication. To exist in their territory, they communicate through diversified means throughout the 20th century. (Signs, advertising inserts, commercial documents...) This communication has its own themes thanks to which craftsmen try to improve the reputation of their business and stand out from the competition. They do therefore advertise.artisans – advertising – market – territory