Salicyl­aldehyde–4-(dimethyl­amino)­pyridine (1/1)

In the title compound, C7H10N2·C7H6O2, the components are linked by an O—H⋯N hydrogen bond. The mean planes of two mol­ecules form a dihedral angle of 78.68 (5)°. The crystal packing exhibits weak non-classical C—H⋯O contacts

11-(3-Chloro-2-hydroxy­prop­oxy)-2,3,9-trimethoxy­chromeno[3,4-b]chromen-12(6H)-one

In the title compound, C22H21ClO8, the rotenoid core is nearly planar (r.m.s. deviation 0.114 Å), with the largest deviations from the least-squares plane being 0.286 (3) and 0.274 (2) Å. An inter­molecular O—H⋯O hydrogen bond links two mol­ecules into a centrosymmetric dimer having an R 2 2(18) ring motif

(4S,5S,6S)-4-Hy­droxy-3-meth­oxy-5-methyl-5,6-ep­oxy­cyclo­hex-2-en-1-one

The title compound, C8H10O4, was isolated from culture extracts of the endophytic fungus Xylaria sp. (PB-30). The cyclo­hexenone ring exhibits a flattened boat conformation. In the crystal structure, mol­ecules related by translation along the b axis are linked into chains through O—H⋯O hydrogen bonds. Weak non-classical C—H⋯O contacts are also observed in the structure

Xyloccensin E

The title compound (also known as phragmalin triacetate), C35H42O14, is a phragmalin-type limonoid extracted from X. rumphii. The mol­ecule consists of eight rings with the orthoacetate group bridged at positions 1, 8 and 9. The two five-carbocyclic rings (A 1 and A 2) and the dioxolane ring (G) adopt a distorted envelope conformation. The 1,3-dioxane ring (E) exists in a chair conformation. The six-carbocyclic rings (B and C) exhibit a twisted-boat conformation. The lactone ring has a half-chair conformation and the furan ring is planar (r.m.s. deviation = 0.002 Å). Rings A 1/B, A 2/B, B/C, C/D and C/G are all cis-fused. The two acet­oxy groups attached to ring B and the furan ring attached to the lactone ring are in equatorial positions. The porous crystal packing exhibits voids of 688 Å3 and weak inter­molecular C—H⋯O inter­actions. The absolute configuration was assigned on the basis of literature data

9,10-Dioxoanthracene-1,4-diyl bis­(4-methyl­benzene­sulfonate)

The title mol­ecule, C28H20O8S2, has a T-shaped conformation. The central 9,10-anthraquinone moiety is bow-shaped with the two outer aromatic rings being inclined to one another by 13.99 (11)°. The benzenesulfonate rings are inclined to one another by 47.35 (12)°, and by 34.51 (11) and 17.88 (11)° to the bridging aromatic ring of the 9,10-anthraquinone moiety. In the crystal, C—H⋯O interactions link the mol­ecules into ribbons in [100]

An Inferential Statistical Analysis of the Key Factors Influencing the Adoption of New Technology by MEEC (MICE) Organizers in Thailand

Purpose: The aim of this study is to examine the adoption of new technology within the Meetings, Exhibitions and Conventions sector in Thailand.   Theoretical framework: An adapted version of the diffusion of innovation theory combined with variables from the Technology Acceptance Model (TAM) is used to define the key variables upon which data is gathered.   Design/Methodology/Approach: The study reviews the MEEC/MICE sector in Thailand and its importance, the existing level of the adoption of new technology and the government plan to encourage further adoption. An online survey of 302 MEEC/MICE Organizers is analyzed using stepwise Multiple Linear regression to estimate the attitude of the organizers toward new technology and which factors have the greatest influence on their intention to adopt new technology further.   Findings: The results indicate that 85% of the study participants are currently adopting MEEC/MICE technological innovation in one way or another, and 99.6% are of the opinion that they will adopt it in the future.  The study also indicates that the business environment, of which government policy is a major factor, can have an influence on both the attitude and the adoption intention of technology, but that their own attitude to technology is the factor with most weight and that the respondent’s attitude to new technology is mostly influenced by their employees’ capability.   Research, practical & social implications: The Thai government is attempting to change the Thai economy from a manufacturing economy to a high value advanced economy.  The further adoption of new technology in this important sector is a vital part of this attempt.   Originality/Value:  The study is the first study in Thailand to use inferential statistical analysis to estimate the most important factors determining MEEC/MICE operators’ adoption of new technology

Spirobisnaphthalenes from the Mangrove-Derived Fungus Rhytidhysteron sp. AS21B

Three new spirobisnaphthalenes (1–3) were isolated from the mangrove-derived fungus Rhytidhysteron sp., together with five known derivatives (4–8). The structures of the compounds were established on the basis of extensive spectroscopic data, and the relative configurations of their stereogenic carbons were determined by a single-crystal X-ray crystallographic analysis. Compounds 3–5 displayed cytotoxicity against both cancer cell lines, MCF-7 and CaSki, while 2 was active only on CaSKi cells

Rhytidenones A–F, Spirobisnaphthalenes from <i>Rhytidhysteron</i> sp. AS21B, an Endophytic Fungus

Rhytidenone A (<b>1</b>), a unique spirobisnaphthalene with a 1,7-dioxaspiro­[4,4]­nonan-2-one motif, and five new spirobisnaphthalenes, rhytidenones B–F (<b>2</b>–<b>6</b>), were isolated from the extract of a cultured fungal endophyte, <i>Rhytidhysteron</i> sp. AS21B. Their structures were elucidated mainly by analysis of NMR spectroscopic data. The structure and configuration of <b>1</b> were further confirmed by single-crystal X-ray diffraction analysis. Compounds <b>3</b> and <b>4</b> exhibited significant inhibitory activity against nitric oxide production from activated macrophages with IC₅₀ values of 0.31 and 3.60 μM, respectively

Rhytidenones A–F, Spirobisnaphthalenes from <i>Rhytidhysteron</i> sp. AS21B, an Endophytic Fungus

Rhytidenone A (<b>1</b>), a unique spirobisnaphthalene with a 1,7-dioxaspiro­[4,4]­nonan-2-one motif, and five new spirobisnaphthalenes, rhytidenones B–F (<b>2</b>–<b>6</b>), were isolated from the extract of a cultured fungal endophyte, <i>Rhytidhysteron</i> sp. AS21B. Their structures were elucidated mainly by analysis of NMR spectroscopic data. The structure and configuration of <b>1</b> were further confirmed by single-crystal X-ray diffraction analysis. Compounds <b>3</b> and <b>4</b> exhibited significant inhibitory activity against nitric oxide production from activated macrophages with IC₅₀ values of 0.31 and 3.60 μM, respectively

Chamigrane Sesquiterpenes from a Basidiomycetous Endophytic Fungus XG8D Associated with Thai Mangrove Xylocarpus granatum

Six new chamigrane sesquiterpenes, merulinols A‒F (1‒6), and four known metabolites (7‒10) were isolated from the culture of the basidiomycetous fungus XG8D, a mangrove-derived endophyte. Their structures were elucidated mainly by 1D and 2D NMR, while the structures of 1 and 2 were further confirmed by single-crystal X-ray diffraction analysis. The in vitro cytotoxicity of all compounds was evaluated against three human cancer cell lines, MCF-7, Hep-G2, and KATO-3. Compounds 3 and 4 selectively displayed cytotoxicity against KATO-3 cells with IC50 values of 35.0 and 25.3 μM, respectively