Re: Recognition and management of psychosis and schizophrenia in children and young people : summary of NICE guidance.

The publication of NICE guidelines relating to the Recognition and management of Psychosis and Schizophrenia in children and young people 1 is to be welcomed given the lack of published guidance in this area, especially concerning the management of young people deemed to be at high risk of psychosis 2,3. However, we feel that the working group may have missed an opportunity to incorporate the views of current adolescent service users. The guideline development process included service-user representation at all stages. However, there was a dearth of published literature in relation to the experiences and treatment preferences of child and adolescent service users with psychosis to draw on 4 although we note the guidelines did not reference our recently published study in this area 5. Indeed, this is a patient group rarely consulted, possibly due to a perception that young people may find it difficult to articulate hallucinatory experiences or have inaccurate recall of events 6,7. However, there is a growing acceptance that eliciting and learning from service users' views is an important means of improving the quality of future health care and research within the NHS 8,9. Indeed, where the evidence base is uncertain, as in the present case, patient preferences may play a more significant role in treatment selection 10. In response to our concerns we are working with our local Early Intervention in Psychosis service to address this issue by offering information to young people describing possible therapeutic options and asking them to state their preferences

Take the first step

Health message on opioid addiction designed for social media.https://thekeep.eiu.edu/healthst_undergrad_campaign_social/1007/thumbnail.jp

A Straining in the Text: Women Writers and the Deconstruction of the Sentimental Plot 1845-1900

In the nineteenth century, most sentimental marriage-plot novels by women include a female bildungsroman that terminates with the heroines containment in marriage. The tension between this bildungsroman and the expectations of the marriage-plot novel are examined as a deconstructive gap through which women interrogated the cultural and social realities of their lives under cover of the socially accepted form of the marriage-plot novel. A discussion of the historical realities of women's lives is presented and an embedded interrogation of this reality in the novels is exposed. This examination is Anglo-American in nature including studies of Charlotte Bronte, Elizabeth Gaskell, Louisa May Alcott and Elizabeth Stuart Phelps. At the heart of this deconstructive gap is the experimentation with female relationships, relationships that progressively emerge as the focus of these novels and the decentering force of the marriage-plot. Specifically, female mentoring relationships, which educate the heroine in the ways of the marriage market and, by implication, in the ways of survival in patriarchy, are the source of experimentation. In addition, the psycho-social underpinnings of female development are explored to facilitate an understanding of the nature of these relationships. All of the authors considered in this study have a self-consciousness about their participation in the sentimental tradition and an irony about the expectations the form contains and the reality that their characters experience. Bronte's Shirley, Gaskell's Wives and Daughters, Alcott's Little Women and Work: A story of Experience, and Phelps's Silent Partner demonstrate the power of female relationships to facilitate private survival in a world marked by separate spheres and limited opportunity. A recurring theme in all these novels is the idleness imposed on middle-class women and the heroine's desire for meaningful work. In a chronological progression, the resolution in marriage becomes increasingly less tolerable and/or satisfying, a progression that culminates in the deconstruction of the marriage closure in alternative communities of women (post-marriage) or single alternatives

Running Late: Exploring the Delayed Supermassive Black Hole Growth Seen by Hydro-Dynamical Simulations

Despite the vast amount of processes that depend on the co-evolution of supermassive black holes (SMBHs) and their host galaxies, their physical relationship is still not fully understood. Observations have revealed a well-constrained scaling relation between SMBH mass and galaxy bulge mass in the local universe. In galaxy formation simulations, a different form of SMBH growth behavior emerges at high redshift: prolonged slow growth in the early universe followed by coherent fueling that results in a rapid increase in the central BH's mass. After this "catch-up" period of rapid growth, the SMBH growth resembles the well documented observed local scaling relation between SMBH mass and galaxy bulge mass. We conduct an in-depth study of these SMBH growth behaviors to explore implications it has on the early universe scaling relation. We construct a simple model, using said behaviors, to predict the quasar luminosity function which can be compared to well-documented observable quantities. To combine the simulation behaviors with a mock catalog of galaxies, we employ mathematical convolution techniques. This involves numerical integration methods over a population of dark matter halos and various models that relate the dark matter halo population to quasar luminosity. The models this study produces to resemble the simulation behaviors contains three free parameters. Thus, we employ a least squares fit method on a three dimensional parameter space to find the free parameters that best fit the predictions of our study to various observational data. These results allow us to systematically quantify the range of allowed scenarios for the emergence of the scaling relation between SMBH mass and galaxy bulge mass observed in the local universe

Double V on the Homefront: African American Women Volunteers in Knoxville, Tennessee During World War II

Many historians have studied World War II and its effect on women, but few look at the efforts of black women in homefront defense. This study addresses the questions in what ways did African American women participate on the homefront? Who volunteered, and how did national African American women\u27s groups motivate members to work for segregationist organizations? Evidence from local and national sources, including Red Cross national memoranda, Red Cross minute books from Knox County, local newspapers, and national African American women\u27s clubs magazines. suggest that African American women volunteered on many different levels in Knoxville. They joined groups directed by national sororities, the U.S.O., the Red Cross, and local church groups. During World War II, African American organizations promoted a non-violent protest against inequality through participation in the war. This thesis focuses on the African American recruiting guidelines of the Red Cross and Joint Army and Navy Boards and committees (U.S.O.) and the volunteerism policies of Alpha Kappa Alpha sorority, the National Association of Colored Graduate Nurses, and the National Association of Colored Women. In addition, it will highlight club women\u27s participation in Knoxville\u27s nursing and first-aid classes, production units, U.S.O.s, and local grass-roots victory efforts

Ken Gelder and Rachael Weaver: The Colonial Kangaroo Hunt.

Review of Ken Gelder and Rachael Weaver: The Colonial Kangaroo Hunt

Victoria Kuttainen, Susann Leibich and Sarah Galletly, Eds., The Transported Imagination: Australian Interwar Magazines and the Geographical Imaginaries of Colonial Modernity

Revie

Understanding the influence of prior plastic loading on subsequent creep in 316H stainless steel via crystal plasticity finite element modelling

Structural components in the thermal power generation industry are regularly exposed to cyclic thermal stresses and as a result, develop complex loading histories which impact their lifetimes. The current assessment methodologies often introduce conservatism which can result in under-predicting the safe lifetimes of plant components. In order to better inform lifetime assessments, it is vitally important to understand both experimentally and through simulations, how the loading history of a material influences the mechanism by which subsequent macromechanical deformation takes place. Crystal plasticity finite element (CPFE) modelling is an effective tool that is able to capture the macroscopic response and meso-scale behaviour of crystalline materials, such as 316H stainless steel. The information gained from CPFE modelling provides a deeper understanding of the physical mechanisms and behaviours that lead to deformation, which will result in better informed lifetime assessments. In this thesis, the predictive capabilities of a crystal plasticity finite element model are scrutinised and novel experimental testing programs are developed.Specific areas of the CPFE model are subjected to a sensitivity analysis study to examine various sources of uncertainty; the input material parameters, the amount of scatter that is produced by altering the initial microstructure, and the influence of the boundary conditions. A further investigation into the predictive capabilities of the model is completed to analyse how thestress/strain response of a single grain is influenced by the crystallographic orientation of itself and the neighbouring grains. The influence of prior plastic deformation on subsequent creep and primary creep regeneration has been investigated experimentally and successfully simulated withthe CPFE model. The experimental results have highlighted the extent to which creep behaviour can be altered and demonstrate the need for accurate modelling of such complex loading cases such that these macromechanical responses can be represented in lifetime assessments

Empirical evidence of nitrogen, water, and phosphorus uptake as functions of fine root mass to inform next-generation terrestrial biosphere models​

We have conducted a multi-factorial greenhouse experiment, aimed to improve the understanding of resource uptake mechanisms in terrestrial biosphere models. By measuring the biomass, nitrogen concentration, transpiration, and phosphorus concentration of Kentucky Bluegrass (POA pratensis), we analyzed the effects of full-factorial nitrogen, phosphorus, and water limitations. Our experiment took place from August to December 2019 in the IES Greenhouse. To analyze our data, our team is using R to run analysis and visualize our experimental findings. We hope that our data findings and subsequent research paper will be utilized by earth system modelers to better understand the ways in which plants receive and use nutrients