2,096 research outputs found

    Another integrable case in the Lorenz model

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    A scaling invariance in the Lorenz model allows one to consider the usually discarded case sigma=0. We integrate it with the third Painlev\'e function.Comment: 3 pages, no figure, to appear in J. Phys.

    Light-mediated strong coupling between a mechanical oscillator and atomic spins one meter apart

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    Engineering strong interactions between quantum systems is essential for many phenomena of quantum physics and technology. Typically, strong coupling relies on short-range forces or on placing the systems in high-quality electromagnetic resonators, restricting the range of the coupling to small distances. We use a free-space laser beam to strongly couple a collective atomic spin and a micromechanical membrane over a distance of one meter in a room-temperature environment. The coupling is highly tunable and allows the observation of normal-mode splitting, coherent energy exchange oscillations, two-mode thermal noise squeezing and dissipative coupling. Our approach to engineer coherent long-distance interactions with light makes it possible to couple very different systems in a modular way, opening up a range of opportunities for quantum control and coherent feedback networks.Comment: 24 pages, 9 figure

    Confirmation Bias in Adoption of Seeker Exemplars in Crowdsourcing Ideation Contests

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    This study examineshow solutionexemplarsthat seekers providein crowdsourcing ideation contestsaffect the scanning, shortlisting, and selection of ideas by solvers; thesethreeideation activities are essential layersin the Knowledge Reuse for Radical Innovation model.Specifically, we consider the role of confirmation bias in solvers’ behaviors and their use of seeker exemplarsinthe ideation activities. We posit that solvers’ use of exemplars is affected by the extent to which the exemplars are consistent with solvers’ prior beliefand by different considerations in different ideation activities. The results from a crowdsourcing ideationcontest experiment largely support our theorizing, as we find that problem-related and problem-unrelated seeker exemplars affecteddifferent ideation activitiesdifferently. This research contributes insights into seeker involvements and solver behaviors in crowdsourcing ideation contests and offers practical implications for seekers

    397: Use of N-acetylcysteine for hepatic veno-occlusive disease prophylaxis in pediatric hematopoietic stem cell transplant patients

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    Biocompatibility of bio based calcium carbonate nanocrystals aragonite polymorph on NIH 3T3 fibroblast cell line

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    Background: Currently, there has been extensive research interest for inorganic nanocrystals such as calcium phosphate, iron oxide, silicone,carbon nanotube and layered double hydroxide as a drug delivery system especially in cancer therapy. However, toxicological screening of suchparticles is paramount importance before use as delivery carrier. In this study we examine the biocompatibility of CaCO3 nanocrystal on NIH 3T3cell line.Material and Methods: Transmission and field emission scanning electron microscopy (TEM and FESEM) were used for the characterisation ofCaCO3 nanocrystals. Cytotoxicity and genotoxic effect of calcium carbonate nanocrystals in cultured mouse embryonic fibroblast NIH 3T3 cellline using various bioassays including MTT, and Neutral red/Trypan blue double-staining assays. LDH, BrdU and reactive oxygen species wereused for toxicity analysis. Cellular morphology was examined by scanning electron microscopy (SEM) and confocal fluorescence microscope.Results: The outcome of the analyses revealed a clear rod-shaped aragonite polymorph of calcium carbonate nanocrystal. The analysed cytotoxic and genotoxicity of CaCO3 nanocrystal on NIH 3T3 cells using different bioassays revealed no significance differences as compared to control. A slight decrease in cell viability was noticed when the cells were exposed to higher concentrations of 200 to 400 ìg/ml, while increase in ROS generation and LDH released at 200 and 400 ìg/ml was observed.Conclusions: The study has shown that CaCO3 nanocrystal is biocompatible and non toxic to NIH 3T3 fibroblast cells. The analysed results offer a promising potential of CaCO3 nanocrystal for the development of  intracellular drugs, genes and other macromolecule delivery systems.Keywords: Biocompatibility; Calcium carbonate; nanocrystals; drugs and Cockle shells
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