1,159 research outputs found
Looking At the Past and Heading to the Future: Meeting Summary of the 6(th) European Workshop on Plant Chromatin 2019 in Cologne, Germany
Produtividade do capim-marandu durante o estabelecimento, após períodos de alagamento
Este trabalho objetivou avaliar o efeito do período de alagamento sobre a produtividade de biomassa da Brachiaria brizantha cv. Marandu. O experimento foi conduzido em casa-de-vegetação em um delineamento inteiramente ao acaso com arranjo fatorial 4x2 e três repetições. Foram avaliados os períodos de 0, 5, 10 e 15 dias de alagamento em duas coletas (final do período de alagamento e 20 dias após a primeira avaliação). O alagamento foi imposto quando as plantas apresentaram média de cinco a seis folhas expandidas, sendo primeiro implantado o tratamento de 15 dias de alagamento, e os demais cinco e dez dias após a implantação deste; 10 e 5 dias de alagamento respectivamente. A partir de então todos foram mantidos na mesma condição do tratamento controle. Nas duas coletas realizadas durante o período experimental, observou-se a produção de matéria seca de folhas (MSF), colmos (MSC), raízes (MSR) e parte aérea total (MST) em g/vaso, além da taxa de acumulo de matéria seca total (TAMST) em g/dia. Os períodos de alagamento influenciaram a composição morfológica da planta principalmente na produção de MSF com decréscimo na produção de 0,0895 g MSF/vaso.dia de alagamento (primeira avaliação) e 0,6603 g MSF/vaso.dia de alagamento (segunda avaliação) ao longo do período de estresse. além de menor produção de MST na segunda avaliação, para plantas que permaneceram em maior período de alagamento, com decréscimo na produção equivalente a 0,9939 g MST/vaso.dia de alagamento
Mutational load may predict risk of progression in patients with Barrett\u27s oesophagus and indefinite for dysplasia: A pilot study
© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. Background and aims Mutational load (ML) has been shown to help risk-stratify those that may progress from non-dysplastic Barrett\u27s oesophagus (BE) to dysplastic disease. Management of patients with BE and indefinite for dysplasia (BE-IND) is challenging and risk stratification tools are lacking. The aim of this pilot study is to evaluate the utility of ML for risk stratification in patients with BE-IND. Methods This is a single-centre, retrospective pilot study evaluating ML quantification in patients with BE-IND. Histology at follow-up endoscopy at least 1 year after the baseline endoscopy was used to determine if a patient progressed to low or high dysplasia. The ML levels were then compared among patients who progressed to dysplasia versus those who did not. Results Thirty-five patients who met the inclusion criteria were identified, and seven met the exclusion criteria. Twenty-eight patients were analysed, of whom eight progressed to low-grade dysplasia (6) and high-grade dysplasia (2). Seven of these eight patients had some level of genomic instability detected in their IND biopsy (ML ≥0.5). Ten of the 20 (50%) who did not progress had no ML level. At an ML cut-off above 1.5, the risk of progression to high-grade dysplasia was 33% vs 0% (p=0.005), with a sensitivity of 100% and a specificity of 85%. Conclusion These results indicate that ML may be able to risk-stratify progression to high-grade dysplasia in BE-IND. Larger studies are needed to confirm these findings
Sward structure management for a maximum short-term intake rate in annual ryegrass.
This study tested the hypothesis that different sward structures, which were constructed by varying the pre- and post-grazing sward heights of annual ryegrass pasture (Lolium multiflorum Lam.) in southern Brazil, affect the short-term intake rate (STIR) by dairy cows. Treatments consisted of four sward-management strategies defined by a combination of two pre- (25 and 15 cm) and two post-grazing sward heights (10 and 5 cm): 15-05, 15-10, 25-05 and 25-10. A completely randomized block design with four replicates was used for the experimental design. The STIR was determined by the double-weighing technique. Jaw movements were evaluated using automatic recorders (IGER Behaviour Recorder). The results showed that treatment 25-10 allowed the animals to collect more herbage with a greater bite mass and thus resulted in a greater STIR. Treatments in which sward height was reduced to 10 cm generally favoured the ingestion process than treatments with a post-grazing sward height of 5 cm
Assessment of Chronic Illness-Related Cognitive Fusion: Preliminary Development and Validation of a New Scale with an IBD Sample
Although research recognizes the advantages of creating specific content measures, no specific measure of chronic illness-related cognitive fusion had been developed to date. The current study presents the development and validation of the Cognitive Fusion Questionnaire-Chronic Illness (CFQ-CI) in a sample of inflammatory bowel disease (IBD) patients and the analysis of the role of this construct in the psychological health of those patients. Results indicated that the 7-item CFQ-CI was a unidimensional measure of cognitive fusion in patients with chronic illnesses, and that scores had adequate/good internal consistency and construct, convergent, and discriminant validity. This study also showed that chronic illness-related cognitive fusion as assessed by the CFQ-CI acted as a mediator in the association between both IBD-related symptoms and shame with quality of life. The development of the CFQ-CI may thus contribute to a better understanding of the mechanisms influencing functional outcomes in chronic illness
Prevalence, risk factors, and outcomes of hospitalized patients with COVID-19 presenting as acute pancreatitis.
Principal components analysis of sward structure and ingestive behaviour of beef cattle managed at levels of herbage allowances in natural pasture.
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