29,050 research outputs found
OGO-3 observations of ELF noise in the magnetosphere - Part 1 - Spatial extent and frequency of occurrence
OGO-3 spectrum analyzer measurements of magnetic noise in magnetospher
Adoption and non-adoption of a shared electronic summary record in England: a mixed-method case study
Publisher version: http://www.bmj.com/content/340/bmj.c3111.full?sid=fcb22308-64fe-4070-9067-15a172b3aea
Recommended from our members
Global analysis of gene expression reveals mRNA superinduction is required for the inducible immune response to a bacterial pathogen.
The inducible innate immune response to infection requires a concerted process of gene expression that is regulated at multiple levels. Most global analyses of the innate immune response have focused on transcription induced by defined immunostimulatory ligands, such as lipopolysaccharide. However, the response to pathogens involves additional complexity, as pathogens interfere with virtually every step of gene expression. How cells respond to pathogen-mediated disruption of gene expression to nevertheless initiate protective responses remains unclear. We previously discovered that a pathogen-mediated blockade of host protein synthesis provokes the production of specific pro-inflammatory cytokines. It remains unclear how these cytokines are produced despite the global pathogen-induced block of translation. We addressed this question by using parallel RNAseq and ribosome profiling to characterize the response of macrophages to infection with the intracellular bacterial pathogen Legionella pneumophila. Our results reveal that mRNA superinduction is required for the inducible immune response to a bacterial pathogen
Multiple spacecraft observations of interplanetary shocks: Characteristics of the upstream ULF turbulence
All interplanetary shocks observed by ISEE-3 and either ISEE-1 or ISEE-2 or both in 1978 and 1979 are examined for evidence of upstream waves. In order to characterize the properties of these shocks it is necessary to determine accurate shock normals. An overdetermined set of equations were inverted to obtain shock normals, velocities and error estimates for all these shocks. Tests of the method indicate it is quite reliable. Using these normals the Mach number and angle were between the interplanetary magnetic field and the shock normal for each shock. The upstream waves were separated into two classes: whistler mode precursors which occur at low Mach numbers and upstream turbulence whose amplitude at Mach numbers greater than 1.5 is controlled by the angle of the field to the shock normal. The former waves are right hand circularly polarized and quite monochromatic. The latter waves are more linearly polarized and have a broadband featureless spectrum
Preliminary Results from Recent Measurements of the Antiprotonic Helium Hyperfine Structure
We report on preliminary results from a systematic study of the hyperfine
(HF) structure of antiprotonic helium. This precise measurement which was
commenced in 2006, has now been completed. Our initial analysis shows no
apparent density or power dependence and therefore the results can be averaged.
The statistical error of the observable M1 transitions is a factor of 60
smaller than that of three body quantum electrodynamic (QED) calculations,
while their difference has been resolved to a precision comparable to theory (a
factor of 10 better than our first measurement). This difference is sensitive
to the antiproton magnetic moment and agreement between theory and experiment
would lead to an increased precision of this parameter, thus providing a test
of CPT invariance.Comment: 6 pages, 4 figure
Semi-Classical Description of Antiproton Capture on Atomic Helium
A semi-classical, many-body atomic model incorporating a momentum-dependent
Heisenberg core to stabilize atomic electrons is used to study antiproton
capture on Helium. Details of the antiproton collisions leading to eventual
capture are presented, including the energy and angular momentum states of
incident antiprotons which result in capture via single or double electron
ionization, i.e. into [He or He], and the
distribution of energy and angular momentum states following the Auger cascade.
These final states are discussed in light of recently reported, anomalously
long-lived antiproton states observed in liquid He.Comment: 15 pages, 9 figures may be obtained from authors, Revte
Initial POLAR MFE observation of substorm signatures in the polar magnetosphere
This paper studies substorm influences in the polar magnetosphere using data from the POLAR magnetic field experiment (MFE). The POLAR spacecraft remains in the high altitude polar magnetosphere for extended periods around apogee. There it can stay at nearly constant altitude through all phases of a substorm, which was not possible on previous missions. We report such an event on March 28, 1996. Ground magnetometers monitored substorm activity, while the POLAR spacecraft, directly over the pole at (ā0.8, ā0.6, 8.5) RE in GSM coordinates, observed a corresponding perturbation in the total magnetic field strength. The total magnetic field first increased, then recovered toward quiet levels, consistent with erosion of magnetic flux from the dayside magnetosphere, followed by transport of that flux to the magnetotail, and eventual onset of tail reconnection and the return of that magnetic flux to the dayside magnetosphere
A technology development program for large space antennas
The design and application of the offset wrap rib and the maypole (hoop/column) antenna configurations are described. The NASA mission model that generically categorizes the classes of user requirements, as well as the methods used to determine critical technologies and requirements are discussed. Performance estimates for the mesh deployable antenna selected for development are presented
A period of calm in Scottish seas: a comprehensive study of ĪR values for the northern British Isles coast and the consequent implications for archaeology and oceanography
The Marine Radiocarbon Reservoir Effect (MRE) is a 14C age offset between contemporaneous
marine- and terrestrially-derived carbon. In Northern Hemisphere surface waters it is of the order of
400 years but temporal and spatial deviations, known as ĪR, occur. This study provides a
comprehensive dataset of 21 ĪR and MRE values for the east coast of Scotland and 21 recalculated
values for the west coast of Scotland and Ireland, for the period c. 3500 BC to 1450 AD. They are
presented as mean, site-specific ĪR and MRE values, together with their associated uncertainties,
calculated as standard errors for predicted values. The ĪR values range from -320 Ā± 35 to +150 Ā± 28
14C years and show no spatial or temporal trends. The MRE values range from 59 Ā± 40 to 531 Ā± 26,
show an almost identical distribution pattern to the ĪR values and again show no spatial or temporal
trends. Results show that ĪR values calculated for a single site using statistically indistinguishable
groups of terrestrial and marine radiocarbon age measurements can produce variability of up to 225
14C years. ĪR is an important factor in the accurate calibration of samples containing marine-derived
carbon for archaeological interpretation but is often also used as an indicator of changes in 14C
specific activity of the oceans, and therefore a proxy for changes in ocean circulation and/or climate.
Using the methods outlined in this paper, it is apparent that ĪR values for the northern part of the
British Isles have been relatively stable, within our ability to quantify non-random variation in the
data. The fact that significant climatic shifts have been recorded during this time, yet these are not
visible in the ĪR data, presents a cautionary tale regarding the use of ĪR to infer large-scale
oceanographic or climatic changes. Upon the exclusion of 5 outliers from the 42 values, the
remaining ĪR values are statistically indistinguishable from one another and range from -142 Ā± 61 to
+40 Ā± 47 14C years. 34 of these values are from Scottish archaeological sites and can be combined to
produce a mean value for Scotland of -47 Ā± 52 14C years for the period 3500 BC to 1450 AD, to be
used only in the absence of site- and period-specific data
- ā¦