Biomimetic Design and Fabrication of Interior Architecture of Tissue Scaffolds Using Solid Freeform Fabrication

Modeling, design and fabrication of tissue scaffolds with intricate architecture, porosity and pore size for desired tissue properties presents a challenge in tissue engineering. This paper will present the details of our development in designing and fabrication of the interior architecture of scaffolds using a novel design approach. The Interior Architecture Design (IAD) approach seeks to generate scaffold layered freeform fabrication tool path without forming complicated 3D CAD scaffold models. This involves: applying the principle of layered manufacturing to determine the scaffold individual layered process planes and layered contour; defining the 2D characteristic patterns of the scaffold building blocks (unit cells) to form the Interior Scaffold Pattern; and the generation of process tool path for freeform fabrication of these scaffolds with the specified interior architecture. Feasibility studies applying the IAD algorithm to example models and the generation of fabrication planning instructions will be presented.Mechanical Engineerin

Stability of Graphene Oxide encapsulated Gold Nanorods for optical sensing purposes

This paper presents the synthesis and characterization of a graphene oxide encapsulated gold nanorod (GNR) complex, where its stability was investigated over time by recording the absorption spectra obtained using a UV/Visible spectrometer over the wavelength region of 200 nm to 1000 nm. Poly Ethylene Glycol (PEG) stablized GNRs were found to be more stable in the presence of graphene oxide dispersions compared to Cetyl Timethyl Ammonium Bromide (CTAB) stabilized GNRs. These GNR complexes, prepared with an active graphene oxide coating on the surface, are presented as a well-suited platform for the development of localized plasmon resonance-based fibre optic biosensors due to the surface functional groups of graphene oxide that can form bio-composites with other biological nanomaterials

Visualizing urban microclimate and quantifying its impact on building energy use in San Francisco

Weather data at nearby airports are usually used in building energy simulation to estimate energy use in buildings or evaluate building design or retrofit options. However, due to urbanization and geography characteristics, local weather conditions can differ significantly from those at airports. This study presents the visualization of 10-year hourly weather data measured at 27 sites in San Francisco, aiming to provide insights into the urban microclimate and urban heat island effect in San Francisco and how they evolve during the recent decade. The 10-year weather data are used in building energy simulations to investigate its influence on energy use and electrical peak demand, which informs the city's policy making on building energy efficiency and resilience. The visualization feature is implemented in CityBES, an open web-based data and computing platform for urban building energy research

Realizing quantum controlled phase-flip gate through quantum dot in silicon slow-light photonic crystal waveguide

We propose a scheme to realize controlled phase gate between two single photons through a single quantum dot in slow-light silicon photonic crystal waveguide. Enhanced Purcell factor and beta factor lead to high gate fidelity over broadband frequencies compared to cavity-assisted system. The excellent physical integration of this silicon photonic crystal waveguide system provides tremendous potential for large-scale quantum information processing.Comment: 9 pages, 3 figure

The Analytical Objective Hysteresis Model (AnOHM v1.0): methodology to determine bulk storage heat flux coefficients

he net storage heat flux is not only a large part of the urban surface energy balance (SEB) but its determination remains a significant challenge. The diurnal hysteresis behaviour found between the net storage heat flux (ΔQS) and net all-wave radiation (Q*) has been captured in the Objective Hysteresis Model (OHM) parametrization of ΔQS. Although, successfully used in urban areas, the limited availability of coefficients for OHM hampers application. To facilitate use, and enhance physical interpretations of the OHM coefficients, an analytical solution of the 1-dimensional advection-diffusion equation of coupled heat and liquid water transport in conjunction with the SEB is conducted, allowing development of AnOHM (Analytical Objective Hysteresis Model). A sensitivity test of AnOHM to surface properties and hydrometeorological forcing is undertaken using a stochastic approach (the Subset Simulation). From this albedo, Bowen ratio and bulk transfer coefficient, solar radiation and wind speed are identified as being critical. AnOHM, driven by local meteorological conditions at five different land use areas, is shown to simulate the ΔQS flux well (RMSE values of ~30 W m−2). The intra-annual dynamics of OHM coefficients to are explored which offers significant potential to enhance modelling of the surface energy balance over a wider range of conditions

Super congruences and Euler numbers

Let $p>3$ be a prime. We prove that $$\sum_{k=0}^{p-1}\binom{2k}{k}/2^k=(-1)^{(p-1)/2}-p^2E_{p-3} (mod p^3),$$ $$\sum_{k=1}^{(p-1)/2}\binom{2k}{k}/k=(-1)^{(p+1)/2}8/3*pE_{p-3} (mod p^2),$$ $$\sum_{k=0}^{(p-1)/2}\binom{2k}{k}^2/16^k=(-1)^{(p-1)/2}+p^2E_{p-3} (mod p^3)$$, where E_0,E_1,E_2,... are Euler numbers. Our new approach is of combinatorial nature. We also formulate many conjectures concerning super congruences and relate most of them to Euler numbers or Bernoulli numbers. Motivated by our investigation of super congruences, we also raise a conjecture on 7 new series for $\pi^2$, $\pi^{-2}$ and the constant $K:=\sum_{k>0}(k/3)/k^2$ (with (-) the Jacobi symbol), two of which are $$\sum_{k=1}^\infty(10k-3)8^k/(k^3\binom{2k}{k}^2\binom{3k}{k})=\pi^2/2$$ and $$\sum_{k>0}(15k-4)(-27)^{k-1}/(k^3\binom{2k}{k}^2\binom{3k}k)=K.$